ID   YP099_YEAST             Reviewed;         118 AA.
AC   O13548; A0A7M4B2U1;
DT   11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   25-MAY-2022, entry version 80.
DE   RecName: Full=Mitochondrial protein YPR099C {ECO:0000303|PubMed:31374566};
GN   OrderedLocusNames=YPR099C; ORFNames=P8283.13A;
OS   Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=559292;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=9169875;
RA   Bussey H., Storms R.K., Ahmed A., Albermann K., Allen E., Ansorge W.,
RA   Araujo R., Aparicio A., Barrell B.G., Badcock K., Benes V., Botstein D.,
RA   Bowman S., Brueckner M., Carpenter J., Cherry J.M., Chung E.,
RA   Churcher C.M., Coster F., Davis K., Davis R.W., Dietrich F.S., Delius H.,
RA   DiPaolo T., Dubois E., Duesterhoeft A., Duncan M., Floeth M., Fortin N.,
RA   Friesen J.D., Fritz C., Goffeau A., Hall J., Hebling U., Heumann K.,
RA   Hilbert H., Hillier L.W., Hunicke-Smith S., Hyman R.W., Johnston M.,
RA   Kalman S., Kleine K., Komp C., Kurdi O., Lashkari D., Lew H., Lin A.,
RA   Lin D., Louis E.J., Marathe R., Messenguy F., Mewes H.-W., Mirtipati S.,
RA   Moestl D., Mueller-Auer S., Namath A., Nentwich U., Oefner P., Pearson D.,
RA   Petel F.X., Pohl T.M., Purnelle B., Rajandream M.A., Rechmann S.,
RA   Rieger M., Riles L., Roberts D., Schaefer M., Scharfe M., Scherens B.,
RA   Schramm S., Schroeder M., Sdicu A.-M., Tettelin H., Urrestarazu L.A.,
RA   Ushinsky S., Vierendeels F., Vissers S., Voss H., Walsh S.V., Wambutt R.,
RA   Wang Y., Wedler E., Wedler H., Winnett E., Zhong W.-W., Zollner A.,
RA   Vo D.H., Hani J.;
RT   "The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI.";
RL   Nature 387:103-105(1997).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=24374639; DOI=10.1534/g3.113.008995;
RA   Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA   Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA   Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT   "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL   G3 (Bethesda) 4:389-398(2014).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=17322287; DOI=10.1101/gr.6037607;
RA   Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F.,
RA   Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J.,
RA   Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J.,
RA   Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D.,
RA   LaBaer J.;
RT   "Approaching a complete repository of sequence-verified protein-encoding
RT   clones for Saccharomyces cerevisiae.";
RL   Genome Res. 17:536-543(2007).
RN   [4]
RP   FUNCTION, SUBCELLULAR LOCATION, AND DISRUPTION PHENOTYPE.
RX   PubMed=31374566; DOI=10.1093/femsyr/foz056;
RA   Sahu P.K., Salim S., Pp M., Chauhan S., Tomar R.S.;
RT   "Reverse genetic analysis of yeast YPR099C/MRPL51 reveals a critical role
RT   of both overlapping ORFs in respiratory growth and MRPL51 in mitochondrial
RT   DNA maintenance.";
RL   FEMS Yeast Res. 19:0-0(2019).
CC   -!- FUNCTION: Essential for the functional mitochondria and respiratory
CC       growth. {ECO:0000269|PubMed:31374566}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000269|PubMed:31374566}.
CC   -!- DISRUPTION PHENOTYPE: Has a respiratory growth defect. Shows partial
CC       growth on nonfermentable carbon source. {ECO:0000269|PubMed:31374566}.
CC   -!- MISCELLANEOUS: Although initially predicted to be a dubious gene
CC       because of an almost complete overlap with MRPL51, it shows transcript
CC       and protein level expression. {ECO:0000269|PubMed:31374566,
CC       ECO:0000305|PubMed:24374639}.
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DR   EMBL; U32445; AAB68088.1; -; Genomic_DNA.
DR   EMBL; AY693278; AAT93297.1; -; Genomic_DNA.
DR   EMBL; BK006949; DAC85312.1; -; Genomic_DNA.
DR   PIR; S69461; S69461.
DR   AlphaFoldDB; O13548; -.
DR   DIP; DIP-4524N; -.
DR   STRING; 4932.YPR099C; -.
DR   PaxDb; O13548; -.
DR   EnsemblFungi; YPR099C_mRNA; YPR099C; YPR099C.
DR   SGD; S000006303; YPR099C.
DR   HOGENOM; CLU_2074990_0_0_1; -.
DR   Proteomes; UP000002311; Chromosome XVI.
DR   GO; GO:0005739; C:mitochondrion; IDA:SGD.
PE   4: Predicted;
KW   Mitochondrion; Reference proteome.
FT   CHAIN           1..118
FT                   /note="Mitochondrial protein YPR099C"
FT                   /id="PRO_0000299824"
SQ   SEQUENCE   118 AA;  13360 MW;  16DDC5E2B31655D5 CRC64;
     MSPSESFNSF SLFSTLSMFK FLTQITFSRP FVYSALNKGC PDFLITSNCI HGNSWPHLSN
     LFEVKNFLMP SEDPPQLQNC KVIFLHGNTN APTPLRPMEF RAIAFTTISP YIRVCVST