YP148_YEAST
ID YP148_YEAST Reviewed; 435 AA.
AC Q06523; D6W4E5;
DT 31-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 03-AUG-2022, entry version 141.
DE RecName: Full=Uncharacterized protein YPR148C;
GN OrderedLocusNames=YPR148C;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=9169875;
RA Bussey H., Storms R.K., Ahmed A., Albermann K., Allen E., Ansorge W.,
RA Araujo R., Aparicio A., Barrell B.G., Badcock K., Benes V., Botstein D.,
RA Bowman S., Brueckner M., Carpenter J., Cherry J.M., Chung E.,
RA Churcher C.M., Coster F., Davis K., Davis R.W., Dietrich F.S., Delius H.,
RA DiPaolo T., Dubois E., Duesterhoeft A., Duncan M., Floeth M., Fortin N.,
RA Friesen J.D., Fritz C., Goffeau A., Hall J., Hebling U., Heumann K.,
RA Hilbert H., Hillier L.W., Hunicke-Smith S., Hyman R.W., Johnston M.,
RA Kalman S., Kleine K., Komp C., Kurdi O., Lashkari D., Lew H., Lin A.,
RA Lin D., Louis E.J., Marathe R., Messenguy F., Mewes H.-W., Mirtipati S.,
RA Moestl D., Mueller-Auer S., Namath A., Nentwich U., Oefner P., Pearson D.,
RA Petel F.X., Pohl T.M., Purnelle B., Rajandream M.A., Rechmann S.,
RA Rieger M., Riles L., Roberts D., Schaefer M., Scharfe M., Scherens B.,
RA Schramm S., Schroeder M., Sdicu A.-M., Tettelin H., Urrestarazu L.A.,
RA Ushinsky S., Vierendeels F., Vissers S., Voss H., Walsh S.V., Wambutt R.,
RA Wang Y., Wedler E., Wedler H., Winnett E., Zhong W.-W., Zollner A.,
RA Vo D.H., Hani J.;
RT "The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI.";
RL Nature 387:103-105(1997).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [3]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=14562095; DOI=10.1038/nature02026;
RA Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W.,
RA Weissman J.S., O'Shea E.K.;
RT "Global analysis of protein localization in budding yeast.";
RL Nature 425:686-691(2003).
RN [4]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-47, AND IDENTIFICATION BY
RP MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=18407956; DOI=10.1074/mcp.m700468-mcp200;
RA Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.;
RT "A multidimensional chromatography technology for in-depth phosphoproteome
RT analysis.";
RL Mol. Cell. Proteomics 7:1389-1396(2008).
RN [5]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=19779198; DOI=10.1126/science.1172867;
RA Holt L.J., Tuch B.B., Villen J., Johnson A.D., Gygi S.P., Morgan D.O.;
RT "Global analysis of Cdk1 substrate phosphorylation sites provides insights
RT into evolution.";
RL Science 325:1682-1686(2009).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:14562095}.
CC Note=Cytoplasmic punctate structures.
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DR EMBL; U40829; AAB68286.1; -; Genomic_DNA.
DR EMBL; BK006949; DAA11561.1; -; Genomic_DNA.
DR PIR; S69035; S69035.
DR RefSeq; NP_015474.1; NM_001184245.1.
DR AlphaFoldDB; Q06523; -.
DR SMR; Q06523; -.
DR BioGRID; 36316; 29.
DR DIP; DIP-3808N; -.
DR IntAct; Q06523; 3.
DR iPTMnet; Q06523; -.
DR MaxQB; Q06523; -.
DR PaxDb; Q06523; -.
DR PRIDE; Q06523; -.
DR EnsemblFungi; YPR148C_mRNA; YPR148C; YPR148C.
DR GeneID; 856271; -.
DR KEGG; sce:YPR148C; -.
DR SGD; S000006352; YPR148C.
DR VEuPathDB; FungiDB:YPR148C; -.
DR eggNOG; ENOG502QZYP; Eukaryota.
DR HOGENOM; CLU_059029_0_0_1; -.
DR InParanoid; Q06523; -.
DR OMA; YRQCVQE; -.
DR BioCyc; YEAST:G3O-34280-MON; -.
DR PRO; PR:Q06523; -.
DR Proteomes; UP000002311; Chromosome XVI.
DR RNAct; Q06523; protein.
DR GO; GO:0005737; C:cytoplasm; HDA:SGD.
DR Gene3D; 1.20.1270.60; -; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR018859; BAR_dom-cont.
DR Pfam; PF10455; BAR_2; 1.
DR SUPFAM; SSF103657; SSF103657; 1.
PE 1: Evidence at protein level;
KW Cytoplasm; Phosphoprotein; Reference proteome.
FT CHAIN 1..435
FT /note="Uncharacterized protein YPR148C"
FT /id="PRO_0000257829"
FT REGION 174..210
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 290..372
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 193..210
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 318..372
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 47
FT /note="Phosphoserine"
FT /evidence="ECO:0007744|PubMed:18407956"
SQ SEQUENCE 435 AA; 49279 MW; B60964F4B7D44B6D CRC64;
MSGYFSGFSL NKITDSIATA AHKTQDTLNN ALANANVNLN DPQTRLSIKS RTRFVQESLG
TVSDISKLPP QYQFLEKKSD SLEKVCKRIL LVSKTFEVEG YDYPPNLTES ISDWWSLNKD
GWFGSKKSES STKKKGSNHD DAFLPRSFAQ AISKAAVDCE CEFQNLEHNE KAELKKKKES
IKTAQTTEAQ GADHNEEDEE DEEDEEDDED LSNLIKVFDS WSTCYKNIDE GKAEMDSMMV
KEFNKKLETL INQDFKKVHD LRKKVEESRL KFDTMRYEVK AKEAELEAKK AEATGEAHSK
DVSAKDISAN TTTSFDETPS TEDEKPKSEG AEEESKKEAN EPTVDDVADR KEDLKSNKVN
DEPPIEESED NKLLEKLEDE FVSNTTAAVE TMEEITDSSE ILGLIKLFQN FQLVYFRQCV
QEVEANLKVL NGLEI
