YP225_YEAST
ID YP225_YEAST Reviewed; 146 AA.
AC Q08971; D6W3E5;
DT 27-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 03-AUG-2022, entry version 148.
DE RecName: Full=Protein PBDC1 homolog;
GN OrderedLocusNames=YPL225W;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=9169875;
RA Bussey H., Storms R.K., Ahmed A., Albermann K., Allen E., Ansorge W.,
RA Araujo R., Aparicio A., Barrell B.G., Badcock K., Benes V., Botstein D.,
RA Bowman S., Brueckner M., Carpenter J., Cherry J.M., Chung E.,
RA Churcher C.M., Coster F., Davis K., Davis R.W., Dietrich F.S., Delius H.,
RA DiPaolo T., Dubois E., Duesterhoeft A., Duncan M., Floeth M., Fortin N.,
RA Friesen J.D., Fritz C., Goffeau A., Hall J., Hebling U., Heumann K.,
RA Hilbert H., Hillier L.W., Hunicke-Smith S., Hyman R.W., Johnston M.,
RA Kalman S., Kleine K., Komp C., Kurdi O., Lashkari D., Lew H., Lin A.,
RA Lin D., Louis E.J., Marathe R., Messenguy F., Mewes H.-W., Mirtipati S.,
RA Moestl D., Mueller-Auer S., Namath A., Nentwich U., Oefner P., Pearson D.,
RA Petel F.X., Pohl T.M., Purnelle B., Rajandream M.A., Rechmann S.,
RA Rieger M., Riles L., Roberts D., Schaefer M., Scharfe M., Scherens B.,
RA Schramm S., Schroeder M., Sdicu A.-M., Tettelin H., Urrestarazu L.A.,
RA Ushinsky S., Vierendeels F., Vissers S., Voss H., Walsh S.V., Wambutt R.,
RA Wang Y., Wedler E., Wedler H., Winnett E., Zhong W.-W., Zollner A.,
RA Vo D.H., Hani J.;
RT "The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI.";
RL Nature 387:103-105(1997).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [3]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=17322287; DOI=10.1101/gr.6037607;
RA Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F.,
RA Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J.,
RA Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J.,
RA Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D.,
RA LaBaer J.;
RT "Approaching a complete repository of sequence-verified protein-encoding
RT clones for Saccharomyces cerevisiae.";
RL Genome Res. 17:536-543(2007).
RN [4]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=14562095; DOI=10.1038/nature02026;
RA Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W.,
RA Weissman J.S., O'Shea E.K.;
RT "Global analysis of protein localization in budding yeast.";
RL Nature 425:686-691(2003).
RN [5]
RP LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
RX PubMed=14562106; DOI=10.1038/nature02046;
RA Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N.,
RA O'Shea E.K., Weissman J.S.;
RT "Global analysis of protein expression in yeast.";
RL Nature 425:737-741(2003).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:14562095}.
CC -!- MISCELLANEOUS: Present with 37500 molecules/cell in log phase SD
CC medium. {ECO:0000269|PubMed:14562106}.
CC -!- SIMILARITY: Belongs to the PBDC1 family. {ECO:0000305}.
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DR EMBL; Z73581; CAA97940.1; -; Genomic_DNA.
DR EMBL; AY692562; AAT92581.1; -; Genomic_DNA.
DR EMBL; BK006949; DAA11211.1; -; Genomic_DNA.
DR PIR; S65244; S65244.
DR RefSeq; NP_015099.1; NM_001184039.1.
DR PDB; 2JYN; NMR; -; A=1-146.
DR PDBsum; 2JYN; -.
DR AlphaFoldDB; Q08971; -.
DR BMRB; Q08971; -.
DR SMR; Q08971; -.
DR BioGRID; 35960; 107.
DR IntAct; Q08971; 3.
DR MINT; Q08971; -.
DR STRING; 4932.YPL225W; -.
DR iPTMnet; Q08971; -.
DR MaxQB; Q08971; -.
DR PaxDb; Q08971; -.
DR PRIDE; Q08971; -.
DR DNASU; 855876; -.
DR EnsemblFungi; YPL225W_mRNA; YPL225W; YPL225W.
DR GeneID; 855876; -.
DR KEGG; sce:YPL225W; -.
DR SGD; S000006146; YPL225W.
DR VEuPathDB; FungiDB:YPL225W; -.
DR eggNOG; KOG4093; Eukaryota.
DR GeneTree; ENSGT00390000016333; -.
DR HOGENOM; CLU_103791_1_0_1; -.
DR InParanoid; Q08971; -.
DR OMA; RIQFYAF; -.
DR BioCyc; YEAST:G3O-34114-MON; -.
DR EvolutionaryTrace; Q08971; -.
DR PRO; PR:Q08971; -.
DR Proteomes; UP000002311; Chromosome XVI.
DR RNAct; Q08971; protein.
DR GO; GO:0005737; C:cytoplasm; HDA:SGD.
DR Gene3D; 1.10.3560.10; -; 1.
DR InterPro; IPR023139; PBDC1-like_dom_sf.
DR InterPro; IPR008476; PBDC1_metazoa/fungi.
DR InterPro; IPR021148; Polysacc_synth_dom.
DR PANTHER; PTHR13410; PTHR13410; 1.
DR Pfam; PF04669; Polysacc_synt_4; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Cytoplasm; Reference proteome.
FT CHAIN 1..146
FT /note="Protein PBDC1 homolog"
FT /id="PRO_0000242144"
FT STRAND 4..6
FT /evidence="ECO:0007829|PDB:2JYN"
FT HELIX 12..36
FT /evidence="ECO:0007829|PDB:2JYN"
FT HELIX 48..58
FT /evidence="ECO:0007829|PDB:2JYN"
FT TURN 60..62
FT /evidence="ECO:0007829|PDB:2JYN"
FT HELIX 65..69
FT /evidence="ECO:0007829|PDB:2JYN"
FT TURN 74..76
FT /evidence="ECO:0007829|PDB:2JYN"
FT HELIX 79..92
FT /evidence="ECO:0007829|PDB:2JYN"
FT TURN 93..95
FT /evidence="ECO:0007829|PDB:2JYN"
FT STRAND 103..108
FT /evidence="ECO:0007829|PDB:2JYN"
FT STRAND 118..121
FT /evidence="ECO:0007829|PDB:2JYN"
FT HELIX 123..135
FT /evidence="ECO:0007829|PDB:2JYN"
FT TURN 136..139
FT /evidence="ECO:0007829|PDB:2JYN"
FT HELIX 140..142
FT /evidence="ECO:0007829|PDB:2JYN"
SQ SEQUENCE 146 AA; 17445 MW; 8A621FD74A720B3C CRC64;
MSTFNAETAD NLEDIEKQFA VVAVEQAETY WKLLTSVPGS KLRLTKFDDE IYENFMERFP
EYKDVERVKK FTEEELKTKE AKERWRKFFT IFEKKIEDYN FGTLLRTDAS AEYGQFTTCF
VVRLQFYAFE IARNKHGLND WIVGQK
