YP245_YEAST
ID YP245_YEAST Reviewed; 454 AA.
AC Q12179; D6W3C6;
DT 27-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 03-AUG-2022, entry version 150.
DE RecName: Full=Uncharacterized protein YPL245W;
GN OrderedLocusNames=YPL245W;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=9169875;
RA Bussey H., Storms R.K., Ahmed A., Albermann K., Allen E., Ansorge W.,
RA Araujo R., Aparicio A., Barrell B.G., Badcock K., Benes V., Botstein D.,
RA Bowman S., Brueckner M., Carpenter J., Cherry J.M., Chung E.,
RA Churcher C.M., Coster F., Davis K., Davis R.W., Dietrich F.S., Delius H.,
RA DiPaolo T., Dubois E., Duesterhoeft A., Duncan M., Floeth M., Fortin N.,
RA Friesen J.D., Fritz C., Goffeau A., Hall J., Hebling U., Heumann K.,
RA Hilbert H., Hillier L.W., Hunicke-Smith S., Hyman R.W., Johnston M.,
RA Kalman S., Kleine K., Komp C., Kurdi O., Lashkari D., Lew H., Lin A.,
RA Lin D., Louis E.J., Marathe R., Messenguy F., Mewes H.-W., Mirtipati S.,
RA Moestl D., Mueller-Auer S., Namath A., Nentwich U., Oefner P., Pearson D.,
RA Petel F.X., Pohl T.M., Purnelle B., Rajandream M.A., Rechmann S.,
RA Rieger M., Riles L., Roberts D., Schaefer M., Scharfe M., Scherens B.,
RA Schramm S., Schroeder M., Sdicu A.-M., Tettelin H., Urrestarazu L.A.,
RA Ushinsky S., Vierendeels F., Vissers S., Voss H., Walsh S.V., Wambutt R.,
RA Wang Y., Wedler E., Wedler H., Winnett E., Zhong W.-W., Zollner A.,
RA Vo D.H., Hani J.;
RT "The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI.";
RL Nature 387:103-105(1997).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [3]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=14562095; DOI=10.1038/nature02026;
RA Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W.,
RA Weissman J.S., O'Shea E.K.;
RT "Global analysis of protein localization in budding yeast.";
RL Nature 425:686-691(2003).
RN [4]
RP LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
RX PubMed=14562106; DOI=10.1038/nature02046;
RA Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N.,
RA O'Shea E.K., Weissman J.S.;
RT "Global analysis of protein expression in yeast.";
RL Nature 425:737-741(2003).
RN [5]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=22814378; DOI=10.1073/pnas.1210303109;
RA Van Damme P., Lasa M., Polevoda B., Gazquez C., Elosegui-Artola A.,
RA Kim D.S., De Juan-Pardo E., Demeyer K., Hole K., Larrea E., Timmerman E.,
RA Prieto J., Arnesen T., Sherman F., Gevaert K., Aldabe R.;
RT "N-terminal acetylome analyses and functional insights of the N-terminal
RT acetyltransferase NatB.";
RL Proc. Natl. Acad. Sci. U.S.A. 109:12449-12454(2012).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:14562095}. Nucleus
CC {ECO:0000269|PubMed:14562095}.
CC -!- MISCELLANEOUS: Present with 1130 molecules/cell in log phase SD medium.
CC {ECO:0000269|PubMed:14562106}.
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DR EMBL; Z67751; CAA91599.1; -; Genomic_DNA.
DR EMBL; Z73601; CAA97966.1; -; Genomic_DNA.
DR EMBL; BK006949; DAA11192.1; -; Genomic_DNA.
DR PIR; S61019; S61019.
DR RefSeq; NP_015079.1; NM_001184059.1.
DR AlphaFoldDB; Q12179; -.
DR BioGRID; 35918; 81.
DR DIP; DIP-3957N; -.
DR IntAct; Q12179; 2.
DR MINT; Q12179; -.
DR STRING; 4932.YPL245W; -.
DR iPTMnet; Q12179; -.
DR MaxQB; Q12179; -.
DR PaxDb; Q12179; -.
DR PRIDE; Q12179; -.
DR EnsemblFungi; YPL245W_mRNA; YPL245W; YPL245W.
DR GeneID; 855831; -.
DR KEGG; sce:YPL245W; -.
DR SGD; S000006166; YPL245W.
DR VEuPathDB; FungiDB:YPL245W; -.
DR eggNOG; ENOG502QRC1; Eukaryota.
DR HOGENOM; CLU_009521_0_0_1; -.
DR InParanoid; Q12179; -.
DR OMA; LRMGSYW; -.
DR BioCyc; YEAST:G3O-34131-MON; -.
DR PRO; PR:Q12179; -.
DR Proteomes; UP000002311; Chromosome XVI.
DR RNAct; Q12179; protein.
DR GO; GO:0005737; C:cytoplasm; HDA:SGD.
DR GO; GO:0005634; C:nucleus; HDA:SGD.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR018647; SLFN_3-like_DNA/RNA_helicase.
DR Pfam; PF09848; DUF2075; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
PE 1: Evidence at protein level;
KW Cytoplasm; Nucleus; Reference proteome.
FT CHAIN 1..454
FT /note="Uncharacterized protein YPL245W"
FT /id="PRO_0000242145"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 454 AA; 52257 MW; B2EEA9FAE16B1498 CRC64;
MHGPTSKAIS RNVRSVKRPR RAPRPVVSTQ AMNKLSNVTL SAEQEKLRER VLSFMRSNLS
QYKSDWKHPA MFVIQGDAGT GKSVILNSLF NEIQKLSQFS PSSEDILHGT HNYLVVNHPE
MLKLYIRISD SFKYISKSSL ERPTSLINNL QKRKVMADVV IVDEAHLLAT SKDAFKRFYG
ENHLKDLMSL CKVLVLVYDD KQALRMGSYW DEGSNNGATL KDFYNEIPPK SRDWYTLKQQ
FRVAAPQNVL NWIDQISVAG KIPPIESVLS KGNADCADDK IKNFDFKIWD DCGAMYEAIK
EKDRQYGQCR MLSTYDFPYR LDGKDYYVEC GDNFKVRWDR YTPREVTPWS ERCDTIDEVG
SVYTIQGFDL NYAGVILGRS IGYDAANDCI KLRPELYDDR AGFTKKKNIH NAEDVKQKII
MNSINVLLTR GVRGLYVYAY DPELRERLLR PSKK