ID   YP53_SCHPO              Reviewed;         567 AA.
AC   B5BP47;
DT   21-MAR-2012, integrated into UniProtKB/Swiss-Prot.
DT   14-OCT-2008, sequence version 1.
DT   25-MAY-2022, entry version 54.
DE   RecName: Full=Uncharacterized transporter C460.03;
GN   ORFNames=SPBC460.03;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=18727152; DOI=10.1002/yea.1613;
RA   Sasaki M., Idiris A., Tada A., Kumagai H., Giga-Hama Y., Tohda H.;
RT   "The gap-filling sequence on the left arm of chromosome 2 in fission yeast
RT   Schizosaccharomyces pombe.";
RL   Yeast 25:673-679(2008).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AB325691; BAG68903.1; -; Genomic_DNA.
DR   AlphaFoldDB; B5BP47; -.
DR   SMR; B5BP47; -.
DR   STRING; 4896.SPBC460.03.1; -.
DR   MaxQB; B5BP47; -.
DR   PaxDb; B5BP47; -.
DR   EnsemblFungi; SPBC460.03.1; SPBC460.03.1:pep; SPBC460.03.
DR   PomBase; SPBC460.03; -.
DR   VEuPathDB; FungiDB:SPBC460.03; -.
DR   eggNOG; KOG0254; Eukaryota.
DR   HOGENOM; CLU_000960_22_3_1; -.
DR   InParanoid; B5BP47; -.
DR   OMA; FRRRGMY; -.
DR   PRO; PR:B5BP47; -.
DR   Proteomes; UP000002485; Chromosome II, gap-filling sequence.
DR   GO; GO:0000329; C:fungal-type vacuole membrane; IDA:PomBase.
DR   GO; GO:0071627; C:integral component of fungal-type vacuolar membrane; ISS:PomBase.
DR   GO; GO:0015174; F:basic amino acid transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:0015179; F:L-amino acid transmembrane transporter activity; ISS:PomBase.
DR   GO; GO:0022857; F:transmembrane transporter activity; IBA:GO_Central.
DR   GO; GO:1990591; P:asparagine transmembrane import into vacuole; IMP:PomBase.
DR   GO; GO:0015802; P:basic amino acid transport; IBA:GO_Central.
DR   GO; GO:0090518; P:L-arginine transmembrane import into vacuole; IMP:PomBase.
DR   GO; GO:0090513; P:L-histidine transmembrane import into vacuole; IMP:PomBase.
DR   GO; GO:0090517; P:L-lysine transmembrane import into vacuole; IMP:PomBase.
DR   GO; GO:0110101; P:L-valine transmembrane import into vacuole; IMP:PomBase.
DR   GO; GO:0055085; P:transmembrane transport; IBA:GO_Central.
DR   Gene3D; 1.20.1250.20; -; 1.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   Pfam; PF07690; MFS_1; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   PROSITE; PS50850; MFS; 1.
PE   3: Inferred from homology;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix;
KW   Transport.
FT   CHAIN           1..567
FT                   /note="Uncharacterized transporter C460.03"
FT                   /id="PRO_0000415921"
FT   TRANSMEM        136..156
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        159..179
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        193..213
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        217..237
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        258..278
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        291..311
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        334..354
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        364..384
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        393..415
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        426..446
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        457..477
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        536..553
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   567 AA;  61632 MW;  2855BDDC7CD1B269 CRC64;
     MNVQKSNNAE ETITPFSEES SLLNSNSYIP ATFVDPTTIP QTSTEDIDIH GFNSIFDIPN
     LAWIEVSLLL NVFLAGFDGT VTASAYTTIG EEFHAANLAS WITTSYLITS TTFQPLYGSF
     SDVLGRRVCL FMASGLFCLG CLWCYFSSGM VSLIFARSFM GIGGGGLITL STIINSDIIP
     TRNRGLFQAF QNLLLGFGAI CGASFGGVLS EVFSWRLCFL VQVPFSVLSI AVGFFFVKNQ
     SGYSRFHHYC VLFKKIDILG GLLLVSGLTS LLLVLTFGSS RSIQTYRPSQ LLLLLGILCI
     VAFVYVESIT EAAPIIPLKL LKGLYSSLVL TTGFLIGLAG YAYLFTLPLF FQLVLGDSPS
     KAGLRLALPS LSTPIGGLIC GILMHRNFRV GKLLFSGVFL MSLGYFLSLF IHPGISPIVL
     GIFLIPANVG QGIGFPSSLF SFIFAFPQNS HATSTSTLYL IRSIGSLFGV GGLSAVIQLT
     LRKKMLADLT KFTDLDSKSI QKIIHDVSKS ISALYELPEA IQEIVLSDYT FSIRKAQQFT
     TICCVLALGL CILKDTIKPR TPSGFRY