ID   YP54_SCHPO              Reviewed;         391 AA.
AC   B5BP48;
DT   21-MAR-2012, integrated into UniProtKB/Swiss-Prot.
DT   14-OCT-2008, sequence version 1.
DT   03-AUG-2022, entry version 50.
DE   RecName: Full=Putative alpha-ketoglutarate-dependent sulfonate dioxygenase;
DE            EC=1.14.11.-;
GN   ORFNames=SPBC460.04c;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=18727152; DOI=10.1002/yea.1613;
RA   Sasaki M., Idiris A., Tada A., Kumagai H., Giga-Hama Y., Tohda H.;
RT   "The gap-filling sequence on the left arm of chromosome 2 in fission yeast
RT   Schizosaccharomyces pombe.";
RL   Yeast 25:673-679(2008).
CC   -!- FUNCTION: Acts as an alpha-ketoglutarate-dependent dioxygenase active
CC       on sulfonates. {ECO:0000250}.
CC   -!- COFACTOR:
CC       Name=Fe(2+); Xref=ChEBI:CHEBI:29033; Evidence={ECO:0000250};
CC       Note=Binds 1 Fe(2+) ion per subunit. {ECO:0000250};
CC   -!- PATHWAY: Organosulfur degradation; alkanesulfonate degradation.
CC   -!- SIMILARITY: Belongs to the TfdA dioxygenase family. {ECO:0000305}.
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DR   EMBL; AB325691; BAG68904.1; -; Genomic_DNA.
DR   AlphaFoldDB; B5BP48; -.
DR   SMR; B5BP48; -.
DR   STRING; 4896.SPBC460.04c.1; -.
DR   PaxDb; B5BP48; -.
DR   EnsemblFungi; SPBC460.04c.1; SPBC460.04c.1:pep; SPBC460.04c.
DR   PomBase; SPBC460.04c; -.
DR   VEuPathDB; FungiDB:SPBC460.04c; -.
DR   eggNOG; ENOG502QT05; Eukaryota.
DR   HOGENOM; CLU_036005_0_1_1; -.
DR   InParanoid; B5BP48; -.
DR   OMA; DANSHER; -.
DR   UniPathway; UPA00338; -.
DR   PRO; PR:B5BP48; -.
DR   Proteomes; UP000002485; Chromosome II, gap-filling sequence.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0016706; F:2-oxoglutarate-dependent dioxygenase activity; IBA:GO_Central.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0000907; F:sulfonate dioxygenase activity; ISO:PomBase.
DR   GO; GO:0046306; P:alkanesulfonate catabolic process; IEA:UniProtKB-UniPathway.
DR   GO; GO:0044273; P:sulfur compound catabolic process; ISO:PomBase.
DR   Gene3D; 3.60.130.10; -; 1.
DR   InterPro; IPR042098; TauD-like_sf.
DR   InterPro; IPR003819; TauD/TfdA-like.
DR   Pfam; PF02668; TauD; 1.
PE   3: Inferred from homology;
KW   Dioxygenase; Iron; Metal-binding; Oxidoreductase; Reference proteome.
FT   CHAIN           1..391
FT                   /note="Putative alpha-ketoglutarate-dependent sulfonate
FT                   dioxygenase"
FT                   /id="PRO_0000415922"
FT   REGION          262..282
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   BINDING         204
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /ligand_note="catalytic"
FT                   /evidence="ECO:0000250"
FT   BINDING         206
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /ligand_note="catalytic"
FT                   /evidence="ECO:0000250"
FT   BINDING         231
FT                   /ligand="2-oxoglutarate"
FT                   /ligand_id="ChEBI:CHEBI:16810"
FT                   /evidence="ECO:0000250"
FT   BINDING         338
FT                   /ligand="2-oxoglutarate"
FT                   /ligand_id="ChEBI:CHEBI:16810"
FT                   /evidence="ECO:0000250"
FT   BINDING         353
FT                   /ligand="Fe cation"
FT                   /ligand_id="ChEBI:CHEBI:24875"
FT                   /ligand_note="catalytic"
FT                   /evidence="ECO:0000250"
FT   BINDING         364
FT                   /ligand="2-oxoglutarate"
FT                   /ligand_id="ChEBI:CHEBI:16810"
FT                   /evidence="ECO:0000250"
FT   BINDING         368
FT                   /ligand="2-oxoglutarate"
FT                   /ligand_id="ChEBI:CHEBI:16810"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   391 AA;  44843 MW;  623285144518A6BE CRC64;
     MATLTETISK ADKHDEKLTD FQYSKKIFNG VHEVEDDKQR TDFTTVRFGD VEKKFAVPKD
     YKYKNVLPTF PNAVYNLTGE LAFEDKGLLA DPKFSNLLKD VTKVEHLARD LGTVLYGIQL
     SKLNDAQKNE LARYIAERGV VYFPDQEQTL EEFQELGQYY GHSHKHGSNS RPFEDKFAEF
     QVVYSDRFSP YDQHAKNNSL RYWHSDVSFE KQPSAQTFFK ALTVPEQGGD TLFISGYAAY
     EALSTPLKKY LEGLTVVHSG KEQSEYHRRS GQHVRLDGDT NAHPIVRTHP VTGWKSLFIS
     PGFTRYIPGI PRGESDAILD YLYQHIANLS QSTVRIKWTS NGVAAWDNRI VIHRATYDHL
     PQTRHLVRIA AQGEVPFFDA NSHERSEDLR E