ID   YP55_SCHPO              Reviewed;         530 AA.
AC   B5BP49;
DT   21-MAR-2012, integrated into UniProtKB/Swiss-Prot.
DT   14-OCT-2008, sequence version 1.
DT   03-AUG-2022, entry version 52.
DE   RecName: Full=Uncharacterized transporter C460.05;
GN   ORFNames=SPBC460.05;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=18727152; DOI=10.1002/yea.1613;
RA   Sasaki M., Idiris A., Tada A., Kumagai H., Giga-Hama Y., Tohda H.;
RT   "The gap-filling sequence on the left arm of chromosome 2 in fission yeast
RT   Schizosaccharomyces pombe.";
RL   Yeast 25:673-679(2008).
CC   -!- SUBCELLULAR LOCATION: Endoplasmic reticulum. Membrane {ECO:0000305};
CC       Multi-pass membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the major facilitator superfamily. Allantoate
CC       permease family. {ECO:0000305}.
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DR   EMBL; AB325691; BAG68905.1; -; Genomic_DNA.
DR   AlphaFoldDB; B5BP49; -.
DR   SMR; B5BP49; -.
DR   STRING; 4896.SPBC460.05.1; -.
DR   PaxDb; B5BP49; -.
DR   EnsemblFungi; SPBC460.05.1; SPBC460.05.1:pep; SPBC460.05.
DR   PomBase; SPBC460.05; -.
DR   VEuPathDB; FungiDB:SPBC460.05; -.
DR   eggNOG; KOG2533; Eukaryota.
DR   HOGENOM; CLU_001265_0_5_1; -.
DR   InParanoid; B5BP49; -.
DR   OMA; CYCVGQI; -.
DR   PRO; PR:B5BP49; -.
DR   Proteomes; UP000002485; Chromosome II, gap-filling sequence.
DR   GO; GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; ISM:PomBase.
DR   GO; GO:0031224; C:intrinsic component of membrane; IBA:GO_Central.
DR   GO; GO:0022857; F:transmembrane transporter activity; ISM:PomBase.
DR   GO; GO:0034220; P:ion transmembrane transport; IEA:UniProt.
DR   GO; GO:0055085; P:transmembrane transport; ISM:PomBase.
DR   Gene3D; 1.20.1250.20; -; 1.
DR   InterPro; IPR011701; MFS.
DR   InterPro; IPR020846; MFS_dom.
DR   InterPro; IPR036259; MFS_trans_sf.
DR   Pfam; PF07690; MFS_1; 1.
DR   SUPFAM; SSF103473; SSF103473; 1.
DR   PROSITE; PS50850; MFS; 1.
PE   3: Inferred from homology;
KW   Endoplasmic reticulum; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..530
FT                   /note="Uncharacterized transporter C460.05"
FT                   /id="PRO_0000415920"
FT   TRANSMEM        83..103
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        124..144
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        147..167
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        181..201
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        211..231
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        244..264
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        323..343
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        346..366
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        375..395
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        404..424
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        436..456
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        471..491
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   REGION          1..33
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..19
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   530 AA;  59473 MW;  DE964B5A1B71009A CRC64;
     MNNMSLKFPD IAINSSESSD DEDPSSKNEK KDGSIKVVKG LTDEKKVFEK AKNDFDEALA
     IIDDDDFEYT KSEDDKVRRK IDFFILPIMC ITYGMQYLDK TAVSYAAVYG MKQEAHLSGY
     VYSWLSTIFY LGYMIAQYPA GYLLQKFPIS YFMFIAAFLW SACVLLMAAC SNRHGLLTLR
     FFSGVFEGCV NPAFVALTAM WYKREEQPVR VVSWYAFNGV AIMVGALLGY GTGHIKGSLQ
     NWKYPFLVIG AISTAWSFVY LFFPQNPVLA RFLNAREKRI AVERVRKNRT GMETKKFKPS
     QALEAFKDPQ VILIVLYNGL CQVTNAMSVF SALIIQGIGY SGINATLLTL PSGAFAVAGM
     IASGIFTHYF KKGRIPLAMT TSSLTIVGSI MIWKIPHSNP WPRVVGVWLF CTISSGNAVI
     LSLLSSNISG YSKKVTVNAT MFLFYSIGNI VSPQLFKAGQ TPEYIEGIQA SLVSVCLFEG
     VLALLAFYYI FENARRDKLL ENNPALGGEI KNEEFLDKTD REQIKFRYVW