ID   YP57_BRUA2              Reviewed;         172 AA.
AC   Q2YJ83; Q57A25; Q9KIS3;
DT   12-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT   07-FEB-2006, sequence version 1.
DT   03-AUG-2022, entry version 76.
DE   RecName: Full=Type IV secretion system putative outer membrane lipoprotein BAB2_0057;
DE   Flags: Precursor;
GN   OrderedLocusNames=BAB2_0057;
OS   Brucella abortus (strain 2308).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Brucellaceae; Brucella/Ochrobactrum group; Brucella.
OX   NCBI_TaxID=359391;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], TRANSCRIPTION, AND FUNCTION.
RX   PubMed=10940027; DOI=10.1128/jb.182.17.4849-4855.2000;
RA   Sieira R., Comerci D.J., Sanchez D.O., Ugalde R.A.;
RT   "A homologue of an operon required for DNA transfer in Agrobacterium is
RT   required in Brucella abortus for virulence and intracellular
RT   multiplication.";
RL   J. Bacteriol. 182:4849-4855(2000).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=2308;
RX   PubMed=16299333; DOI=10.1128/iai.73.12.8353-8361.2005;
RA   Chain P.S., Comerci D.J., Tolmasky M.E., Larimer F.W., Malfatti S.A.,
RA   Vergez L.M., Aguero F., Land M.L., Ugalde R.A., Garcia E.;
RT   "Whole-genome analyses of speciation events in pathogenic Brucellae.";
RL   Infect. Immun. 73:8353-8361(2005).
CC   -!- FUNCTION: The virB operon is essential for intracellular survival and
CC       is not involved in the invasion process. Constitutes a major
CC       determinant of virulence in mice. This protein is essential for
CC       pathogenesis in mice but is not required for intracellular survival.
CC       {ECO:0000269|PubMed:10940027}.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000305}; Lipid-anchor
CC       {ECO:0000255|PROSITE-ProRule:PRU00303}.
CC   -!- MISCELLANEOUS: Transcription is turned on at the beginning of the
CC       stationary phase of vegetative growth.
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DR   EMBL; AF226278; AAF73905.1; -; Genomic_DNA.
DR   EMBL; AM040265; CAJ12223.1; -; Genomic_DNA.
DR   RefSeq; WP_002966521.1; NZ_KN046823.1.
DR   AlphaFoldDB; Q2YJ83; -.
DR   SMR; Q2YJ83; -.
DR   STRING; 359391.BAB2_0057; -.
DR   EnsemblBacteria; CAJ12223; CAJ12223; BAB2_0057.
DR   GeneID; 3827894; -.
DR   KEGG; bmf:BAB2_0057; -.
DR   HOGENOM; CLU_125850_0_0_5; -.
DR   OMA; SNDYREP; -.
DR   BioCyc; MetaCyc:BAB_RS26630-MON; -.
DR   Proteomes; UP000002719; Chromosome II.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   Gene3D; 3.30.1330.60; -; 1.
DR   InterPro; IPR006665; OmpA-like.
DR   InterPro; IPR036737; OmpA-like_sf.
DR   SUPFAM; SSF103088; SSF103088; 1.
DR   PROSITE; PS51123; OMPA_2; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Lipoprotein; Membrane; Palmitate; Reference proteome;
KW   Signal; Virulence.
FT   SIGNAL          1..15
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   CHAIN           16..172
FT                   /note="Type IV secretion system putative outer membrane
FT                   lipoprotein BAB2_0057"
FT                   /id="PRO_0000291445"
FT   DOMAIN          58..172
FT                   /note="OmpA-like"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00473"
FT   LIPID           16
FT                   /note="N-palmitoyl cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
FT   LIPID           16
FT                   /note="S-diacylglycerol cysteine"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00303"
SQ   SEQUENCE   172 AA;  19028 MW;  BEE06DB62310185E CRC64;
     MRTLVMVACA VSLAACSSPP KPPTVSGRHR IPINSPAAQE ELRLQVFPQE PTAQATMWPA
     RPPKQTVNVY FPQDVTVFRP TSAQINQLHT LLWPVPKHIN VRGLTDNNCP PPGDTQVARV
     RALAIYNWLI NQGVPASRIT ISYAPVKDYA SNAPLSPGRV LNRRVDIEIL RK