ID   YPC1_ECOLX              Reviewed;         239 AA.
AC   P18351; P97141; P97142;
DT   01-NOV-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1991, sequence version 2.
DT   25-MAY-2022, entry version 97.
DE   RecName: Full=Uncharacterized 27.6 kDa protein;
DE   AltName: Full=ORF 239;
OS   Escherichia coli.
OG   Plasmid IncN pCU1, and Plasmid pR.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=562;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   PLASMID=IncN pCU1;
RX   PubMed=2205534; DOI=10.1016/0378-1119(90)90155-k;
RA   Krishnan B.R., Fobert P.R., Seitzer U., Iyer V.N.;
RT   "Mutations within the replicon of the IncN plasmid pCU1 that affect its
RT   Escherichia coli polA-independence but not its autonomous replication
RT   ability.";
RL   Gene 91:1-7(1990).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   PLASMID=pR;
RX   PubMed=8492801; DOI=10.1007/bf00291991;
RA   Gigliani F., Ciotta C., Del Grosso M.F., Battaglia P.A.;
RT   "pR plasmid replication provides evidence that single-stranded DNA induces
RT   the SOS system in vivo.";
RL   Mol. Gen. Genet. 238:333-338(1993).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-48.
RC   PLASMID=IncN pCU1;
RX   PubMed=2828186; DOI=10.1016/0378-1119(87)90377-5;
RA   Kozlowski M., Thatte V., Lau P.C.K., Visentin L.P., Iyer V.N.;
RT   "Isolation and structure of the replicon of the promiscuous plasmid pCU1.";
RL   Gene 58:217-228(1987).
CC   -!- FUNCTION: Mutations in ORF 239 affects the incN plasmid pUC1 E.coli
CC       polA-independence but not its autonomous replication ability.
CC   -!- SIMILARITY: Belongs to the initiator RepB protein family.
CC       {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAA98069.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC       Sequence=AAA98070.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; M18262; AAA98068.1; -; Genomic_DNA.
DR   EMBL; M18262; AAA98069.1; ALT_INIT; Genomic_DNA.
DR   EMBL; M18262; AAA98070.1; ALT_INIT; Genomic_DNA.
DR   EMBL; S61747; AAP13930.1; -; Genomic_DNA.
DR   PIR; JQ0682; QQEC27.
DR   RefSeq; WP_000359513.1; NZ_WSWX01000100.1.
DR   RefSeq; YP_001096385.1; NC_009132.1.
DR   RefSeq; YP_006954520.1; NC_019098.1.
DR   RefSeq; YP_009061013.1; NC_024974.1.
DR   RefSeq; YP_009068563.1; NC_025141.1.
DR   AlphaFoldDB; P18351; -.
DR   SMR; P18351; -.
DR   GeneID; 64209499; -.
DR   GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:InterPro.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR   Gene3D; 1.10.10.10; -; 2.
DR   InterPro; IPR000525; Initiator_Rep_prot.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF01051; Rep_3; 1.
DR   SUPFAM; SSF46785; SSF46785; 2.
PE   3: Inferred from homology;
KW   Plasmid.
FT   CHAIN           1..239
FT                   /note="Uncharacterized 27.6 kDa protein"
FT                   /id="PRO_0000068532"
FT   CONFLICT        44..48
FT                   /note="SVSED -> FSKRR (in Ref. 2)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   239 AA;  27592 MW;  5D41D9034F837BB6 CRC64;
     MDKLLNKKIK VKQSNELTEA AYYLSLKAKR VLWLCLMQTY FTASVSEDDD EMAVLGDSTF
     KVKVADYQQI FQVSRNQAIK DVKEGVFELS RSAVIFYPKE GSFDCVARPW LTEAGSRSAR
     GIWEIEFNHK LLRYIYGLTN QFTTYSLRDC GSLRNPRTIR LYESLAQFKS SGLWVTTHAW
     LNDRFLLPES QQKNLAELKR SFLDPALKQI NEKTPLLAKY SIDDSGKFLF SIIDKQNPV