ID   YPDB_ECO57              Reviewed;         244 AA.
AC   P0AE40; P77742;
DT   06-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   06-DEC-2005, sequence version 1.
DT   03-AUG-2022, entry version 101.
DE   RecName: Full=Transcriptional regulatory protein YpdB {ECO:0000250|UniProtKB:P0AE39};
GN   Name=ypdB; OrderedLocusNames=Z3646, ECs3261;
OS   Escherichia coli O157:H7.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83334;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
RX   PubMed=11206551; DOI=10.1038/35054089;
RA   Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J.,
RA   Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G.,
RA   Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J.,
RA   Davis N.W., Lim A., Dimalanta E.T., Potamousis K., Apodaca J.,
RA   Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A.,
RA   Blattner F.R.;
RT   "Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
RL   Nature 409:529-533(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
RX   PubMed=11258796; DOI=10.1093/dnares/8.1.11;
RA   Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K.,
RA   Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T.,
RA   Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T., Kuhara S.,
RA   Shiba T., Hattori M., Shinagawa H.;
RT   "Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and
RT   genomic comparison with a laboratory strain K-12.";
RL   DNA Res. 8:11-22(2001).
CC   -!- FUNCTION: Member of the two-component regulatory system YpdA/YpdB. YpdB
CC       regulates expression of yhjX by binding to its promoter region.
CC       {ECO:0000250|UniProtKB:P0AE39}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- PTM: Phosphorylated by YpdA. {ECO:0000250}.
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DR   EMBL; AE005174; AAG57507.1; -; Genomic_DNA.
DR   EMBL; BA000007; BAB36684.1; -; Genomic_DNA.
DR   PIR; E91036; E91036.
DR   PIR; G85880; G85880.
DR   RefSeq; NP_311288.1; NC_002695.1.
DR   RefSeq; WP_001295458.1; NZ_SWKA01000005.1.
DR   AlphaFoldDB; P0AE40; -.
DR   SMR; P0AE40; -.
DR   STRING; 155864.EDL933_3550; -.
DR   PRIDE; P0AE40; -.
DR   EnsemblBacteria; AAG57507; AAG57507; Z3646.
DR   EnsemblBacteria; BAB36684; BAB36684; ECs_3261.
DR   GeneID; 67416782; -.
DR   GeneID; 915637; -.
DR   KEGG; ece:Z3646; -.
DR   KEGG; ecs:ECs_3261; -.
DR   PATRIC; fig|386585.9.peg.3405; -.
DR   eggNOG; COG3279; Bacteria.
DR   HOGENOM; CLU_000445_14_1_6; -.
DR   OMA; DIHMPDF; -.
DR   Proteomes; UP000000558; Chromosome.
DR   Proteomes; UP000002519; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000160; P:phosphorelay signal transduction system; IEA:UniProtKB-KW.
DR   InterPro; IPR011006; CheY-like_superfamily.
DR   InterPro; IPR007492; LytTR_DNA-bd_dom.
DR   InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR   InterPro; IPR039420; WalR-like.
DR   PANTHER; PTHR48111; PTHR48111; 1.
DR   Pfam; PF04397; LytTR; 1.
DR   Pfam; PF00072; Response_reg; 1.
DR   SMART; SM00850; LytTR; 1.
DR   SMART; SM00448; REC; 1.
DR   SUPFAM; SSF52172; SSF52172; 1.
DR   PROSITE; PS50930; HTH_LYTTR; 1.
DR   PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; DNA-binding; Phosphoprotein; Reference proteome; Transcription;
KW   Transcription regulation; Two-component regulatory system.
FT   CHAIN           1..244
FT                   /note="Transcriptional regulatory protein YpdB"
FT                   /id="PRO_0000081382"
FT   DOMAIN          2..116
FT                   /note="Response regulatory"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
FT   DOMAIN          139..244
FT                   /note="HTH LytTR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00112"
FT   MOD_RES         53
FT                   /note="4-aspartylphosphate"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
SQ   SEQUENCE   244 AA;  28721 MW;  679EA97A44F1260B CRC64;
     MKVIIVEDEF LAQQELSWLI KEHSQMEIVG TFDDGLDVLK FLQHNRVDAI FLDINIPSLD
     GVLLAQNISQ FAHKPFIVFI TAWKEHAVEA FELEAFDYIL KPYQESRITG MLQKLEAAWQ
     QQQTSSTPAA TVTRENDTIN LVKDERIIVT PINDIYYAEA HEKMTFVYTR RESYVMPMNI
     TEFCSKLPPS HFFRCHRSFC VNLNKIREIE PWFNNTYILR LKDLDFEVPV SRSKVKEFRQ
     LMHL