ID   YPDB_ECOL6              Reviewed;         245 AA.
AC   Q8FFE0;
DT   23-APR-2003, integrated into UniProtKB/Swiss-Prot.
DT   23-APR-2003, sequence version 2.
DT   25-MAY-2022, entry version 108.
DE   RecName: Full=Transcriptional regulatory protein YpdB {ECO:0000250|UniProtKB:P0AE39};
GN   Name=ypdB; OrderedLocusNames=c2920;
OS   Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=199310;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CFT073 / ATCC 700928 / UPEC;
RX   PubMed=12471157; DOI=10.1073/pnas.252529799;
RA   Welch R.A., Burland V., Plunkett G. III, Redford P., Roesch P., Rasko D.,
RA   Buckles E.L., Liou S.-R., Boutin A., Hackett J., Stroud D., Mayhew G.F.,
RA   Rose D.J., Zhou S., Schwartz D.C., Perna N.T., Mobley H.L.T.,
RA   Donnenberg M.S., Blattner F.R.;
RT   "Extensive mosaic structure revealed by the complete genome sequence of
RT   uropathogenic Escherichia coli.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:17020-17024(2002).
CC   -!- FUNCTION: Member of the two-component regulatory system YpdA/YpdB. YpdB
CC       regulates expression of yhjX by binding to its promoter region.
CC       {ECO:0000250|UniProtKB:P0AE39}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- PTM: Phosphorylated by YpdA. {ECO:0000250}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAN81370.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; AE014075; AAN81370.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_001350316.1; NC_004431.1.
DR   AlphaFoldDB; Q8FFE0; -.
DR   SMR; Q8FFE0; -.
DR   STRING; 199310.c2920; -.
DR   EnsemblBacteria; AAN81370; AAN81370; c2920.
DR   KEGG; ecc:c2920; -.
DR   eggNOG; COG3279; Bacteria.
DR   HOGENOM; CLU_000445_14_1_6; -.
DR   OMA; DIHMPDF; -.
DR   Proteomes; UP000001410; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0000160; P:phosphorelay signal transduction system; IEA:UniProtKB-KW.
DR   InterPro; IPR011006; CheY-like_superfamily.
DR   InterPro; IPR007492; LytTR_DNA-bd_dom.
DR   InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR   InterPro; IPR039420; WalR-like.
DR   PANTHER; PTHR48111; PTHR48111; 1.
DR   Pfam; PF04397; LytTR; 1.
DR   Pfam; PF00072; Response_reg; 1.
DR   SMART; SM00850; LytTR; 1.
DR   SMART; SM00448; REC; 1.
DR   SUPFAM; SSF52172; SSF52172; 1.
DR   PROSITE; PS50930; HTH_LYTTR; 1.
DR   PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; DNA-binding; Phosphoprotein; Transcription;
KW   Transcription regulation; Two-component regulatory system.
FT   CHAIN           1..245
FT                   /note="Transcriptional regulatory protein YpdB"
FT                   /id="PRO_0000081384"
FT   DOMAIN          2..116
FT                   /note="Response regulatory"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
FT   DOMAIN          140..245
FT                   /note="HTH LytTR-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00112"
FT   MOD_RES         53
FT                   /note="4-aspartylphosphate"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00169"
SQ   SEQUENCE   245 AA;  28866 MW;  4249E0E8072E5CBC CRC64;
     MKVIIVEDEF LAQQELSWLI KEHSQMEIVG TFDDGLDVLK FLQHNRVDAI FLDINIPSLD
     GVLLAQNISQ FAHKPFIVFI TAWKEHAVEA FELEAFDYIL KPYQESRITG MLQKLEAAWQ
     QQQTSSTTPA ATVTRENDTI NLVKDERIIV TPINDIYYAE AHEKMTFVYT RRESYVMPMN
     ITEFFSKLPP SHFFRCHRSF CVNLNKIREI EPWFNNTYIL RLKDLDFEVP VSRSKVKEFR
     QLMHL