ID   YPEA_ECOLI              Reviewed;         141 AA.
AC   P76539; Q2MAJ2;
DT   27-MAR-2002, integrated into UniProtKB/Swiss-Prot.
DT   27-MAR-2002, sequence version 2.
DT   03-AUG-2022, entry version 138.
DE   RecName: Full=Acetyltransferase YpeA;
DE            EC=2.3.1.-;
GN   Name=ypeA; OrderedLocusNames=b2434, JW2427;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
CC   -!- SIMILARITY: Belongs to the acetyltransferase family. YpeA subfamily.
CC       {ECO:0000305}.
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DR   EMBL; U00096; AAC75487.2; -; Genomic_DNA.
DR   EMBL; AP009048; BAE76714.1; -; Genomic_DNA.
DR   PIR; A65018; A65018.
DR   RefSeq; NP_416929.4; NC_000913.3.
DR   RefSeq; WP_000405996.1; NZ_LN832404.1.
DR   PDB; 4QUS; X-ray; 1.28 A; A/B=1-141.
DR   PDB; 4QVT; X-ray; 1.95 A; A/B/C/D/E/F/G/H=1-141.
DR   PDBsum; 4QUS; -.
DR   PDBsum; 4QVT; -.
DR   AlphaFoldDB; P76539; -.
DR   SMR; P76539; -.
DR   BioGRID; 4260749; 17.
DR   DIP; DIP-28085N; -.
DR   IntAct; P76539; 9.
DR   STRING; 511145.b2434; -.
DR   jPOST; P76539; -.
DR   PaxDb; P76539; -.
DR   PRIDE; P76539; -.
DR   EnsemblBacteria; AAC75487; AAC75487; b2434.
DR   EnsemblBacteria; BAE76714; BAE76714; BAE76714.
DR   GeneID; 946917; -.
DR   KEGG; ecj:JW2427; -.
DR   KEGG; eco:b2434; -.
DR   PATRIC; fig|1411691.4.peg.4297; -.
DR   EchoBASE; EB3920; -.
DR   eggNOG; COG0456; Bacteria.
DR   HOGENOM; CLU_013985_34_1_6; -.
DR   InParanoid; P76539; -.
DR   OMA; IAGFDGW; -.
DR   PhylomeDB; P76539; -.
DR   BioCyc; EcoCyc:G7269-MON; -.
DR   PRO; PR:P76539; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0008080; F:N-acetyltransferase activity; IEA:InterPro.
DR   HAMAP; MF_01127; Acetyltransf_YpeA; 1.
DR   InterPro; IPR023072; Acetyltransferase_YpeA.
DR   InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR   InterPro; IPR000182; GNAT_dom.
DR   Pfam; PF00583; Acetyltransf_1; 1.
DR   SUPFAM; SSF55729; SSF55729; 1.
DR   PROSITE; PS51186; GNAT; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Acyltransferase; Reference proteome; Transferase.
FT   CHAIN           1..141
FT                   /note="Acetyltransferase YpeA"
FT                   /id="PRO_0000074620"
FT   DOMAIN          1..141
FT                   /note="N-acetyltransferase"
FT   STRAND          2..5
FT                   /evidence="ECO:0007829|PDB:4QUS"
FT   HELIX           8..10
FT                   /evidence="ECO:0007829|PDB:4QUS"
FT   HELIX           11..20
FT                   /evidence="ECO:0007829|PDB:4QUS"
FT   HELIX           30..40
FT                   /evidence="ECO:0007829|PDB:4QUS"
FT   HELIX           42..44
FT                   /evidence="ECO:0007829|PDB:4QUS"
FT   STRAND          45..50
FT                   /evidence="ECO:0007829|PDB:4QUS"
FT   STRAND          53..62
FT                   /evidence="ECO:0007829|PDB:4QUS"
FT   STRAND          67..74
FT                   /evidence="ECO:0007829|PDB:4QUS"
FT   HELIX           76..78
FT                   /evidence="ECO:0007829|PDB:4QVT"
FT   STRAND          80..82
FT                   /evidence="ECO:0007829|PDB:4QUS"
FT   HELIX           83..97
FT                   /evidence="ECO:0007829|PDB:4QUS"
FT   STRAND          102..107
FT                   /evidence="ECO:0007829|PDB:4QUS"
FT   HELIX           112..120
FT                   /evidence="ECO:0007829|PDB:4QUS"
FT   STRAND          124..126
FT                   /evidence="ECO:0007829|PDB:4QVT"
FT   STRAND          127..136
FT                   /evidence="ECO:0007829|PDB:4QUS"
SQ   SEQUENCE   141 AA;  16312 MW;  F1A9B1A22E37377F CRC64;
     MEIRVFRQED FEEVITLWER CDLLRPWNDP EMDIERKMNH DVSLFLVAEV NGDVVGTVMG
     GYDGHRGSAY YLGVHPEFRG RGIANALLNR LEKKLIARGC PKIQINVPED NDMVLGMYER
     LGYEHADVLS LGKRLIEDEE Y