ID   YPEA_SHIFL              Reviewed;         141 AA.
AC   P63422; Q8FFA4; Q8XBI6;
DT   11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   25-MAY-2022, entry version 100.
DE   RecName: Full=Acetyltransferase YpeA {ECO:0000255|HAMAP-Rule:MF_01127};
DE            EC=2.3.1.- {ECO:0000255|HAMAP-Rule:MF_01127};
GN   Name=ypeA {ECO:0000255|HAMAP-Rule:MF_01127};
GN   OrderedLocusNames=SF2487, S2635;
OS   Shigella flexneri.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=623;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=301 / Serotype 2a;
RX   PubMed=12384590; DOI=10.1093/nar/gkf566;
RA   Jin Q., Yuan Z., Xu J., Wang Y., Shen Y., Lu W., Wang J., Liu H., Yang J.,
RA   Yang F., Zhang X., Zhang J., Yang G., Wu H., Qu D., Dong J., Sun L.,
RA   Xue Y., Zhao A., Gao Y., Zhu J., Kan B., Ding K., Chen S., Cheng H.,
RA   Yao Z., He B., Chen R., Ma D., Qiang B., Wen Y., Hou Y., Yu J.;
RT   "Genome sequence of Shigella flexneri 2a: insights into pathogenicity
RT   through comparison with genomes of Escherichia coli K12 and O157.";
RL   Nucleic Acids Res. 30:4432-4441(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700930 / 2457T / Serotype 2a;
RX   PubMed=12704152; DOI=10.1128/iai.71.5.2775-2786.2003;
RA   Wei J., Goldberg M.B., Burland V., Venkatesan M.M., Deng W., Fournier G.,
RA   Mayhew G.F., Plunkett G. III, Rose D.J., Darling A., Mau B., Perna N.T.,
RA   Payne S.M., Runyen-Janecky L.J., Zhou S., Schwartz D.C., Blattner F.R.;
RT   "Complete genome sequence and comparative genomics of Shigella flexneri
RT   serotype 2a strain 2457T.";
RL   Infect. Immun. 71:2775-2786(2003).
CC   -!- SIMILARITY: Belongs to the acetyltransferase family. YpeA subfamily.
CC       {ECO:0000255|HAMAP-Rule:MF_01127}.
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DR   EMBL; AE005674; AAN43992.2; -; Genomic_DNA.
DR   EMBL; AE014073; AAP17807.1; -; Genomic_DNA.
DR   RefSeq; NP_708285.2; NC_004337.2.
DR   RefSeq; WP_000406000.1; NZ_WPGW01000057.1.
DR   PDB; 2PDO; X-ray; 2.00 A; A/B/C/D/E/F/G/H=1-141.
DR   PDBsum; 2PDO; -.
DR   AlphaFoldDB; P63422; -.
DR   SMR; P63422; -.
DR   STRING; 198214.SF2487; -.
DR   EnsemblBacteria; AAN43992; AAN43992; SF2487.
DR   EnsemblBacteria; AAP17807; AAP17807; S2635.
DR   GeneID; 1025585; -.
DR   GeneID; 67416831; -.
DR   KEGG; sfl:SF2487; -.
DR   KEGG; sfx:S2635; -.
DR   PATRIC; fig|198214.7.peg.2972; -.
DR   HOGENOM; CLU_013985_34_1_6; -.
DR   OMA; IAGFDGW; -.
DR   OrthoDB; 1390922at2; -.
DR   EvolutionaryTrace; P63422; -.
DR   Proteomes; UP000001006; Chromosome.
DR   Proteomes; UP000002673; Chromosome.
DR   GO; GO:0008080; F:N-acetyltransferase activity; IEA:InterPro.
DR   HAMAP; MF_01127; Acetyltransf_YpeA; 1.
DR   InterPro; IPR023072; Acetyltransferase_YpeA.
DR   InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR   InterPro; IPR000182; GNAT_dom.
DR   Pfam; PF00583; Acetyltransf_1; 1.
DR   SUPFAM; SSF55729; SSF55729; 1.
DR   PROSITE; PS51186; GNAT; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Acyltransferase; Reference proteome; Transferase.
FT   CHAIN           1..141
FT                   /note="Acetyltransferase YpeA"
FT                   /id="PRO_0000074625"
FT   DOMAIN          1..141
FT                   /note="N-acetyltransferase"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01127"
FT   STRAND          1..5
FT                   /evidence="ECO:0007829|PDB:2PDO"
FT   HELIX           8..10
FT                   /evidence="ECO:0007829|PDB:2PDO"
FT   HELIX           11..20
FT                   /evidence="ECO:0007829|PDB:2PDO"
FT   HELIX           30..40
FT                   /evidence="ECO:0007829|PDB:2PDO"
FT   STRAND          45..50
FT                   /evidence="ECO:0007829|PDB:2PDO"
FT   STRAND          53..62
FT                   /evidence="ECO:0007829|PDB:2PDO"
FT   STRAND          67..74
FT                   /evidence="ECO:0007829|PDB:2PDO"
FT   HELIX           76..78
FT                   /evidence="ECO:0007829|PDB:2PDO"
FT   HELIX           83..97
FT                   /evidence="ECO:0007829|PDB:2PDO"
FT   STRAND          102..110
FT                   /evidence="ECO:0007829|PDB:2PDO"
FT   HELIX           112..120
FT                   /evidence="ECO:0007829|PDB:2PDO"
FT   STRAND          127..136
FT                   /evidence="ECO:0007829|PDB:2PDO"
SQ   SEQUENCE   141 AA;  16326 MW;  F0B8B0B23F36267F CRC64;
     MEIRVFRQED FEEVITLWER CDLLRPWNDP EMDIERKMNH DVSLFLVAEV NGEVVGTVMG
     GYDGHRGSAY YLGVHPEFRG RGIANALLNR LEKKLIARGC PKIQINVPED NDMVLGMYER
     LGYEHADVLS LGKRLIEDEE Y