ID   YPEL1_CHLAE             Reviewed;         119 AA.
AC   Q65Z59;
DT   09-NOV-2004, integrated into UniProtKB/Swiss-Prot.
DT   25-OCT-2004, sequence version 1.
DT   03-AUG-2022, entry version 43.
DE   RecName: Full=Protein yippee-like 1;
GN   Name=YPEL1;
OS   Chlorocebus aethiops (Green monkey) (Cercopithecus aethiops).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Chlorocebus.
OX   NCBI_TaxID=9534;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=15556292; DOI=10.1016/j.gene.2004.06.014;
RA   Hosono K., Sasaki T., Minoshima S., Shimizu N.;
RT   "Identification and characterization of a novel gene family YPEL in a wide
RT   spectrum of eukaryotic species.";
RL   Gene 340:31-43(2004).
CC   -!- FUNCTION: May play a role in epithelioid conversion of fibroblasts.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the yippee family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AB160977; BAD51386.1; -; mRNA.
DR   AlphaFoldDB; Q65Z59; -.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   InterPro; IPR034751; Yippee.
DR   InterPro; IPR004910; Yippee/Mis18/Cereblon.
DR   InterPro; IPR039058; Yippee_fam.
DR   PANTHER; PTHR13848; PTHR13848; 1.
DR   Pfam; PF03226; Yippee-Mis18; 1.
DR   PROSITE; PS51792; YIPPEE; 1.
PE   3: Inferred from homology;
KW   Metal-binding; Nucleus; Zinc.
FT   CHAIN           1..119
FT                   /note="Protein yippee-like 1"
FT                   /id="PRO_0000212380"
FT   DOMAIN          19..116
FT                   /note="Yippee"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01128"
FT   MOTIF           99..104
FT                   /note="Nuclear localization signal"
FT                   /evidence="ECO:0000255"
FT   BINDING         23
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01128"
FT   BINDING         26
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01128"
FT   BINDING         79
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01128"
FT   BINDING         82
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01128"
SQ   SEQUENCE   119 AA;  13575 MW;  E91C058FA8C6D81F CRC64;
     MVKMTKSKTF QAYLPNCHRT YSCIHCRAHL ANHDELISKS FQGSQGRAYL FNSVVNVGCG
     PAEERVLLTG LHAVADIYCE NCKTTLGWKY EHAFESSQKY KEGKFIIELA HMIKDNGWE