ID   YPEL3_BOVIN             Reviewed;         119 AA.
AC   A6QPH8;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   05-MAY-2009, sequence version 2.
DT   03-AUG-2022, entry version 55.
DE   RecName: Full=Protein yippee-like 3;
GN   Name=YPEL3;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Fetal cerebellum;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in proliferation and apoptosis in myeloid precursor
CC       cells. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- PTM: Probably ubiquitinated leading to its degradation by the
CC       proteasome. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the yippee family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAI49330.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; BC149329; AAI49330.1; ALT_INIT; mRNA.
DR   RefSeq; NP_001192338.1; NM_001205409.1.
DR   AlphaFoldDB; A6QPH8; -.
DR   STRING; 9913.ENSBTAP00000011920; -.
DR   PaxDb; A6QPH8; -.
DR   GeneID; 787498; -.
DR   KEGG; bta:787498; -.
DR   CTD; 83719; -.
DR   eggNOG; KOG3399; Eukaryota.
DR   HOGENOM; CLU_043857_5_2_1; -.
DR   InParanoid; A6QPH8; -.
DR   OrthoDB; 1431042at2759; -.
DR   Proteomes; UP000009136; Unplaced.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   InterPro; IPR034751; Yippee.
DR   InterPro; IPR004910; Yippee/Mis18/Cereblon.
DR   InterPro; IPR039058; Yippee_fam.
DR   PANTHER; PTHR13848; PTHR13848; 1.
DR   Pfam; PF03226; Yippee-Mis18; 1.
DR   PROSITE; PS51792; YIPPEE; 1.
PE   3: Inferred from homology;
KW   Metal-binding; Nucleus; Reference proteome; Ubl conjugation; Zinc.
FT   CHAIN           1..119
FT                   /note="Protein yippee-like 3"
FT                   /id="PRO_0000373877"
FT   DOMAIN          19..116
FT                   /note="Yippee"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01128"
FT   BINDING         23
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01128"
FT   BINDING         26
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01128"
FT   BINDING         79
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01128"
FT   BINDING         82
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01128"
SQ   SEQUENCE   119 AA;  13608 MW;  A35E852DEB1FFBB4 CRC64;
     MVRISKPKTF QAYLDDCHRR YSCAHCRAHL ANHDDLISKS FQGSQGRAYL FNSVVNVGCG
     PAEERVLLTG LHAVADIHCE NCKTTLGWKY EQAFESSQKY KEGKYIIELN HMIKDNGWD