ID   YPEL3_DANRE             Reviewed;         119 AA.
AC   Q6NWI4;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 89.
DE   RecName: Full=Protein yippee-like 3;
GN   Name=ypel3; Synonyms=ypel1;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Jaeger S., Meyer C., Maity S., Esguerra C.V., Behn-Krappa A., Haardt M.;
RT   "Cloning and expression of Ypel1 from zebrafish.";
RL   Submitted (NOV-2002) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Kidney;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May be involved in proliferation and apoptosis in myeloid
CC       precursor cells. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the yippee family. {ECO:0000305}.
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DR   EMBL; AY185349; AAO64479.1; -; mRNA.
DR   EMBL; BC067578; AAH67578.1; -; mRNA.
DR   EMBL; BC154300; AAI54301.1; -; mRNA.
DR   RefSeq; NP_997955.1; NM_212790.1.
DR   AlphaFoldDB; Q6NWI4; -.
DR   STRING; 7955.ENSDARP00000099958; -.
DR   PaxDb; Q6NWI4; -.
DR   PRIDE; Q6NWI4; -.
DR   Ensembl; ENSDART00000113843; ENSDARP00000099958; ENSDARG00000055510.
DR   Ensembl; ENSDART00000136001; ENSDARP00000113056; ENSDARG00000055510.
DR   GeneID; 368214; -.
DR   KEGG; dre:368214; -.
DR   CTD; 83719; -.
DR   ZFIN; ZDB-GENE-030516-4; ypel3.
DR   eggNOG; KOG3399; Eukaryota.
DR   GeneTree; ENSGT00940000161514; -.
DR   HOGENOM; CLU_043857_5_2_1; -.
DR   InParanoid; Q6NWI4; -.
DR   OMA; CCCGQII; -.
DR   OrthoDB; 1431042at2759; -.
DR   PhylomeDB; Q6NWI4; -.
DR   TreeFam; TF313936; -.
DR   PRO; PR:Q6NWI4; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 3.
DR   Bgee; ENSDARG00000055510; Expressed in mature ovarian follicle and 33 other tissues.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0007420; P:brain development; IMP:ZFIN.
DR   InterPro; IPR034751; Yippee.
DR   InterPro; IPR004910; Yippee/Mis18/Cereblon.
DR   InterPro; IPR039058; Yippee_fam.
DR   PANTHER; PTHR13848; PTHR13848; 1.
DR   Pfam; PF03226; Yippee-Mis18; 1.
DR   PROSITE; PS51792; YIPPEE; 1.
PE   3: Inferred from homology;
KW   Apoptosis; Metal-binding; Nucleus; Reference proteome; Zinc.
FT   CHAIN           1..119
FT                   /note="Protein yippee-like 3"
FT                   /id="PRO_0000373878"
FT   DOMAIN          19..116
FT                   /note="Yippee"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01128"
FT   BINDING         23
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01128"
FT   BINDING         26
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01128"
FT   BINDING         79
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01128"
FT   BINDING         82
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01128"
SQ   SEQUENCE   119 AA;  13615 MW;  2C2D76D9F4B207D9 CRC64;
     MVKQTKAKTF QAYLDSCHRR YSCVHCRAHL ANHDDLISKS FQGSQGRAYL FNSVVNVGCG
     PAEERLLLTG LHAVADIYCE NCHTTLGWKY EQAFELSQKY KEGKFIIELS HMIKDNGWD