ID   YPEL3_ORYLA             Reviewed;         119 AA.
AC   Q65Z54;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   25-OCT-2004, sequence version 1.
DT   03-AUG-2022, entry version 69.
DE   RecName: Full=Protein yippee-like 3;
DE   AltName: Full=Protein yippee-like a;
GN   Name=ypel3; Synonyms=ypela;
OS   Oryzias latipes (Japanese rice fish) (Japanese killifish).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC   Oryzias.
OX   NCBI_TaxID=8090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=Cab;
RX   PubMed=15556292; DOI=10.1016/j.gene.2004.06.014;
RA   Hosono K., Sasaki T., Minoshima S., Shimizu N.;
RT   "Identification and characterization of a novel gene family YPEL in a wide
RT   spectrum of eukaryotic species.";
RL   Gene 340:31-43(2004).
CC   -!- FUNCTION: May be involved in proliferation and apoptosis in myeloid
CC       precursor cells. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the yippee family. {ECO:0000305}.
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DR   EMBL; AB160982; BAD51391.1; -; mRNA.
DR   RefSeq; NP_001098180.1; NM_001104710.1.
DR   AlphaFoldDB; Q65Z54; -.
DR   STRING; 8090.ENSORLP00000014925; -.
DR   Ensembl; ENSORLT00000014926; ENSORLP00000014925; ENSORLG00000011915.
DR   Ensembl; ENSORLT00000034522; ENSORLP00000040474; ENSORLG00000011915.
DR   Ensembl; ENSORLT00015013573; ENSORLP00015022221; ENSORLG00015001508.
DR   Ensembl; ENSORLT00020018460; ENSORLP00020028805; ENSORLG00020012491.
DR   Ensembl; ENSORLT00020018463; ENSORLP00020028808; ENSORLG00020012491.
DR   GeneID; 100049286; -.
DR   KEGG; ola:100049286; -.
DR   CTD; 83719; -.
DR   eggNOG; KOG3399; Eukaryota.
DR   GeneTree; ENSGT00940000161514; -.
DR   HOGENOM; CLU_043857_5_2_1; -.
DR   InParanoid; Q65Z54; -.
DR   OMA; CCCGQII; -.
DR   OrthoDB; 1431042at2759; -.
DR   TreeFam; TF313936; -.
DR   Proteomes; UP000001038; Chromosome 8.
DR   Proteomes; UP000265180; Chromosome 8.
DR   Proteomes; UP000265200; Chromosome 8.
DR   Bgee; ENSORLG00000011915; Expressed in blastula and 14 other tissues.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0007420; P:brain development; IEA:Ensembl.
DR   InterPro; IPR034751; Yippee.
DR   InterPro; IPR004910; Yippee/Mis18/Cereblon.
DR   InterPro; IPR039058; Yippee_fam.
DR   PANTHER; PTHR13848; PTHR13848; 1.
DR   Pfam; PF03226; Yippee-Mis18; 1.
DR   PROSITE; PS51792; YIPPEE; 1.
PE   3: Inferred from homology;
KW   Apoptosis; Metal-binding; Nucleus; Reference proteome; Zinc.
FT   CHAIN           1..119
FT                   /note="Protein yippee-like 3"
FT                   /id="PRO_0000373879"
FT   DOMAIN          19..116
FT                   /note="Yippee"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01128"
FT   BINDING         23
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01128"
FT   BINDING         26
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01128"
FT   BINDING         79
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01128"
FT   BINDING         82
FT                   /ligand="Zn(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29105"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01128"
SQ   SEQUENCE   119 AA;  13617 MW;  7C3076D066EFA9A1 CRC64;
     MVKLTKAKTF QAYLDSCHRR YSCVHCRAHL ANHDDLISKS FQGSQGRAYL FNSVVNVGCG
     PAEERLLLTG LHAVADIYCE NCHTTLGWKY EQAFELSQKY KEGKYIIELS HMIKDNGWD