YPEL4_MOUSE
ID YPEL4_MOUSE Reviewed; 127 AA.
AC Q65Z93;
DT 26-APR-2005, integrated into UniProtKB/Swiss-Prot.
DT 25-OCT-2004, sequence version 1.
DT 03-AUG-2022, entry version 110.
DE RecName: Full=Protein yippee-like 4;
GN Name=Ypel4;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], AND TISSUE SPECIFICITY.
RX PubMed=15556292; DOI=10.1016/j.gene.2004.06.014;
RA Hosono K., Sasaki T., Minoshima S., Shimizu N.;
RT "Identification and characterization of a novel gene family YPEL in a wide
RT spectrum of eukaryotic species.";
RL Gene 340:31-43(2004).
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus.
CC -!- TISSUE SPECIFICITY: Detected in brain, spleen and testis.
CC {ECO:0000269|PubMed:15556292}.
CC -!- SIMILARITY: Belongs to the yippee family. {ECO:0000305}.
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DR EMBL; AB098743; BAD51384.1; -; mRNA.
DR CCDS; CCDS16192.1; -.
DR RefSeq; NP_001005342.1; NM_001005342.2.
DR RefSeq; XP_006499529.1; XM_006499466.3.
DR AlphaFoldDB; Q65Z93; -.
DR BioGRID; 232321; 2.
DR STRING; 10090.ENSMUSP00000088231; -.
DR PhosphoSitePlus; Q65Z93; -.
DR PaxDb; Q65Z93; -.
DR PRIDE; Q65Z93; -.
DR ProteomicsDB; 275229; -.
DR Antibodypedia; 65159; 25 antibodies from 14 providers.
DR DNASU; 241525; -.
DR Ensembl; ENSMUST00000090729; ENSMUSP00000088231; ENSMUSG00000034059.
DR GeneID; 241525; -.
DR KEGG; mmu:241525; -.
DR UCSC; uc008kjc.1; mouse.
DR CTD; 219539; -.
DR MGI; MGI:3605071; Ypel4.
DR VEuPathDB; HostDB:ENSMUSG00000034059; -.
DR eggNOG; KOG3399; Eukaryota.
DR GeneTree; ENSGT00940000161443; -.
DR HOGENOM; CLU_043857_5_2_1; -.
DR InParanoid; Q65Z93; -.
DR OMA; PVMPSCE; -.
DR OrthoDB; 1431042at2759; -.
DR PhylomeDB; Q65Z93; -.
DR TreeFam; TF313936; -.
DR BioGRID-ORCS; 241525; 0 hits in 72 CRISPR screens.
DR PRO; PR:Q65Z93; -.
DR Proteomes; UP000000589; Chromosome 2.
DR RNAct; Q65Z93; protein.
DR Bgee; ENSMUSG00000034059; Expressed in cerebellar cortex and 146 other tissues.
DR ExpressionAtlas; Q65Z93; baseline and differential.
DR Genevisible; Q65Z93; MM.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR InterPro; IPR034751; Yippee.
DR InterPro; IPR004910; Yippee/Mis18/Cereblon.
DR InterPro; IPR039058; Yippee_fam.
DR PANTHER; PTHR13848; PTHR13848; 1.
DR Pfam; PF03226; Yippee-Mis18; 1.
DR PROSITE; PS51792; YIPPEE; 1.
PE 2: Evidence at transcript level;
KW Metal-binding; Nucleus; Phosphoprotein; Reference proteome; Zinc.
FT CHAIN 1..127
FT /note="Protein yippee-like 4"
FT /id="PRO_0000212393"
FT DOMAIN 27..124
FT /note="Yippee"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01128"
FT BINDING 31
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01128"
FT BINDING 34
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01128"
FT BINDING 87
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01128"
FT BINDING 90
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01128"
FT MOD_RES 92
FT /note="Phosphothreonine"
FT /evidence="ECO:0000250|UniProtKB:Q5XID5"
FT MOD_RES 93
FT /note="Phosphothreonine"
FT /evidence="ECO:0000250|UniProtKB:Q5XID5"
FT MOD_RES 98
FT /note="Phosphotyrosine"
FT /evidence="ECO:0000250|UniProtKB:Q5XID5"
SQ SEQUENCE 127 AA; 14315 MW; D99894D7D6388121 CRC64;
MPSCDPGPAP ACLPTKTFRS YLPRCHRTYS CVHCRAHLAK HDELISKSFQ GSHGRAYLFN
SVVNVGCGPA EQRLLLTGLH SVADIFCESC KTTLGWKYEQ AFETSQKYKE GKYIIEMSHM
VKDNGWD
