YPF03_PLAF7
ID YPF03_PLAF7 Reviewed; 875 AA.
AC Q8IM00; A0A144A595;
DT 10-FEB-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 25-MAY-2022, entry version 63.
DE RecName: Full=Uncharacterized protein PF3D7_1409500;
GN ORFNames=PF14_0093, PF3D7_1409500;
OS Plasmodium falciparum (isolate 3D7).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX NCBI_TaxID=36329;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=3D7;
RX PubMed=12368864; DOI=10.1038/nature01097;
RA Gardner M.J., Hall N., Fung E., White O., Berriman M., Hyman R.W.,
RA Carlton J.M., Pain A., Nelson K.E., Bowman S., Paulsen I.T., James K.D.,
RA Eisen J.A., Rutherford K.M., Salzberg S.L., Craig A., Kyes S., Chan M.-S.,
RA Nene V., Shallom S.J., Suh B., Peterson J., Angiuoli S., Pertea M.,
RA Allen J., Selengut J., Haft D., Mather M.W., Vaidya A.B., Martin D.M.A.,
RA Fairlamb A.H., Fraunholz M.J., Roos D.S., Ralph S.A., McFadden G.I.,
RA Cummings L.M., Subramanian G.M., Mungall C., Venter J.C., Carucci D.J.,
RA Hoffman S.L., Newbold C., Davis R.W., Fraser C.M., Barrell B.G.;
RT "Genome sequence of the human malaria parasite Plasmodium falciparum.";
RL Nature 419:498-511(2002).
RN [2] {ECO:0000305}
RP SYNTHESIS OF 231-257, AND POSSIBLE CANDIDATE MALARIA EPITOPE.
RX PubMed=17653272; DOI=10.1371/journal.pone.0000645;
RA Villard V., Agak G.W., Frank G., Jafarshad A., Servis C., Nebie I.,
RA Sirima S.B., Felger I., Arevalo-Herrera M., Herrera S., Heitz F.,
RA Baecker V., Druilhe P., Kajava A.V., Corradin G.;
RT "Rapid identification of malaria vaccine candidates based on alpha-helical
RT coiled coil protein motif.";
RL PLoS ONE 2:E645-E645(2007).
CC -!- BIOTECHNOLOGY: Possible candidate for an effective malaria vaccine as
CC determined by epitope response in sera. {ECO:0000269|PubMed:17653272}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LN999946; CZT99803.1; -; Genomic_DNA.
DR RefSeq; XP_001348266.1; XM_001348230.1.
DR AlphaFoldDB; Q8IM00; -.
DR SMR; Q8IM00; -.
DR EnsemblProtists; CZT99803; CZT99803; PF3D7_1409500.
DR GeneID; 811674; -.
DR KEGG; pfa:PF3D7_1409500; -.
DR VEuPathDB; PlasmoDB:PF3D7_1409500; -.
DR HOGENOM; CLU_328606_0_0_1; -.
DR OMA; DKINHKK; -.
DR Proteomes; UP000001450; Chromosome 14.
PE 1: Evidence at protein level;
KW Merozoite; Reference proteome.
FT CHAIN 1..875
FT /note="Uncharacterized protein PF3D7_1409500"
FT /id="PRO_0000361763"
FT REGION 29..48
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 481..510
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 680..705
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 30..48
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 495..510
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 685..705
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 875 AA; 104076 MW; 39F5B655CAD359B1 CRC64;
MKDYNDNIHR PNPHNLYNNI SLLCPPKMKG NSENLSTNNN PNLTGKNIKV SNRHDKMKDI
HIHKLPDVEN ISSDMNPKSS KMFSFKNINH NKEENEIHLK DKYSFEKRED DMYNMSVSNM
HKVPIHKQNI YSKNNYNTSV CLQQNKKETN NISYINNIHN TMCITNNKND HSVEHKINIY
NNKYNYNNTF LCNKKLCTQK IIQYIGKNQN TKHPLHSLYH TNVVGMNKFN SSNNLSDQIN
ILNNNIQHIN STFNNLRQNN IYKNNDSIEL FINNNLKSGD TNKYATFYKN VKISEKNNMY
KQKEDKKQIN NKNPYIFTCQ KYFMRPSNVL HNIQNCGIHK KKKKKKKNHQ IKHRSFHNIY
KQINIINDQI DLINNKINKN SKDQNRAHIL EISPLSLPSY IEYKNKNNNI FSSYFAHPNN
KTHNFKKIKM IKKNISNPFN KEEPCGEKKN SPQVNDSKSF RYFDHSTCNN NYHNKEYMKK
EQKSHLHSNH NINHEKGSDP SYNLNTKNTK NVTNTNDQTC IYEDHTFEKA VENNKVMYLK
NKPIQSKLLK LNNQILNNTD QKKYEKCIDH GDTCNNKDEK NIKCTYKIDD ILCSYNNGNN
IKYEREVIKI TNKYRNALEK WRYKFVHKNK TTKRNITSSN QKGKCNFNIF KINKHINKKK
NKKIKKIESN KYGNMYNFVD KKVNNNQGNK KKNEKKNEKK NDKINDTIND KINHKINHKK
NDKINHKKND KINHKKNDKI NHKKNDKINN KINHKKNMIP NQKPINNMIK YNIKNKKKIY
NDTNDHADNR NIHSHIHKKV PNKKDNNINH MYYDNNNNIN QPISYIHTAY DNVCHQINND
DHCIPLSCVI KNRKTRRSRK NKNLFNNKKN YTNEP