ID   YPF04_PLAF7             Reviewed;         198 AA.
AC   Q8IM04; A0A144A197; A0A144A1W9;
DT   10-FEB-2009, integrated into UniProtKB/Swiss-Prot.
DT   21-SEP-2011, sequence version 2.
DT   03-AUG-2022, entry version 67.
DE   RecName: Full=Uncharacterized protein PF3D7_1409200;
GN   ORFNames=PF14_0089, PF3D7_1409200.1;
OS   Plasmodium falciparum (isolate 3D7).
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC   Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX   NCBI_TaxID=36329;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=3D7;
RX   PubMed=12368864; DOI=10.1038/nature01097;
RA   Gardner M.J., Hall N., Fung E., White O., Berriman M., Hyman R.W.,
RA   Carlton J.M., Pain A., Nelson K.E., Bowman S., Paulsen I.T., James K.D.,
RA   Eisen J.A., Rutherford K.M., Salzberg S.L., Craig A., Kyes S., Chan M.-S.,
RA   Nene V., Shallom S.J., Suh B., Peterson J., Angiuoli S., Pertea M.,
RA   Allen J., Selengut J., Haft D., Mather M.W., Vaidya A.B., Martin D.M.A.,
RA   Fairlamb A.H., Fraunholz M.J., Roos D.S., Ralph S.A., McFadden G.I.,
RA   Cummings L.M., Subramanian G.M., Mungall C., Venter J.C., Carucci D.J.,
RA   Hoffman S.L., Newbold C., Davis R.W., Fraser C.M., Barrell B.G.;
RT   "Genome sequence of the human malaria parasite Plasmodium falciparum.";
RL   Nature 419:498-511(2002).
RN   [2] {ECO:0000305}
RP   SYNTHESIS OF 109-135, AND POSSIBLE CANDIDATE MALARIA EPITOPE.
RX   PubMed=17653272; DOI=10.1371/journal.pone.0000645;
RA   Villard V., Agak G.W., Frank G., Jafarshad A., Servis C., Nebie I.,
RA   Sirima S.B., Felger I., Arevalo-Herrera M., Herrera S., Heitz F.,
RA   Baecker V., Druilhe P., Kajava A.V., Corradin G.;
RT   "Rapid identification of malaria vaccine candidates based on alpha-helical
RT   coiled coil protein motif.";
RL   PLoS ONE 2:E645-E645(2007).
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=2;
CC       Name=1;
CC         IsoId=Q8IM04-1; Sequence=Displayed;
CC       Name=2;
CC         IsoId=Q8IM04-2; Sequence=VSP_061283;
CC   -!- BIOTECHNOLOGY: Possible candidate for an effective malaria vaccine as
CC       determined by epitope response in sera. {ECO:0000269|PubMed:17653272}.
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DR   EMBL; LN999946; CZT99799.1; -; Genomic_DNA.
DR   EMBL; LN999946; CZT99800.1; -; Genomic_DNA.
DR   RefSeq; XP_001348262.2; XM_001348226.2.
DR   AlphaFoldDB; Q8IM04; -.
DR   SMR; Q8IM04; -.
DR   STRING; 5833.PF14_0089.1; -.
DR   EnsemblProtists; CZT99799; CZT99799; PF3D7_1409200.2. [Q8IM04-2]
DR   EnsemblProtists; CZT99800; CZT99800; PF3D7_1409200.1. [Q8IM04-1]
DR   GeneID; 811670; -.
DR   KEGG; pfa:PF3D7_1409200.1; -.
DR   VEuPathDB; PlasmoDB:PF3D7_1409200; -.
DR   HOGENOM; CLU_1457232_0_0_1; -.
DR   InParanoid; Q8IM04; -.
DR   OMA; YINNIVM; -.
DR   OrthoDB; 1372407at2759; -.
DR   PhylomeDB; Q8IM04; -.
DR   Proteomes; UP000001450; Chromosome 14.
PE   1: Evidence at protein level;
KW   Alternative splicing; Coiled coil; Merozoite; Reference proteome.
FT   CHAIN           1..198
FT                   /note="Uncharacterized protein PF3D7_1409200"
FT                   /id="PRO_0000361764"
FT   REGION          72..95
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          106..136
FT                   /evidence="ECO:0000255"
FT   VAR_SEQ         4..16
FT                   /note="SKFFCKSLKFFMH -> N (in isoform 2)"
FT                   /evidence="ECO:0000305"
FT                   /id="VSP_061283"
SQ   SEQUENCE   198 AA;  23555 MW;  CD076CC1DC819D3E CRC64;
     MIKSKFFCKS LKFFMHPYSK IKNEKSFIDL NFIKGYSNFI KKKCVPYDKK KYIFCNKNRL
     ISNVGNKINK KESEEQYDSD DDNDKLVLND DEDDEKKQVH INNKTEATNI TNINKNIENI
     KNDMSNLNNM NDSNQKIKMK NKGKYDSDVI IMYDHFFQLP QNFLSSKLSE EEIEYINTGI
     YNPDFDNYIN NIVMKKKK