ID   YPF05_PLAF7             Reviewed;        1070 AA.
AC   Q8IIG7; A0A143ZYR6;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   21-SEP-2011, sequence version 2.
DT   25-MAY-2022, entry version 83.
DE   RecName: Full=Uncharacterized protein PF3D7_1120000;
GN   ORFNames=PF11_0207, PF3D7_1120000;
OS   Plasmodium falciparum (isolate 3D7).
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC   Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX   NCBI_TaxID=36329;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=3D7;
RX   PubMed=12368864; DOI=10.1038/nature01097;
RA   Gardner M.J., Hall N., Fung E., White O., Berriman M., Hyman R.W.,
RA   Carlton J.M., Pain A., Nelson K.E., Bowman S., Paulsen I.T., James K.D.,
RA   Eisen J.A., Rutherford K.M., Salzberg S.L., Craig A., Kyes S., Chan M.-S.,
RA   Nene V., Shallom S.J., Suh B., Peterson J., Angiuoli S., Pertea M.,
RA   Allen J., Selengut J., Haft D., Mather M.W., Vaidya A.B., Martin D.M.A.,
RA   Fairlamb A.H., Fraunholz M.J., Roos D.S., Ralph S.A., McFadden G.I.,
RA   Cummings L.M., Subramanian G.M., Mungall C., Venter J.C., Carucci D.J.,
RA   Hoffman S.L., Newbold C., Davis R.W., Fraser C.M., Barrell B.G.;
RT   "Genome sequence of the human malaria parasite Plasmodium falciparum.";
RL   Nature 419:498-511(2002).
RN   [2] {ECO:0000305}
RP   SYNTHESIS OF 535-571, AND POSSIBLE CANDIDATE MALARIA EPITOPE.
RX   PubMed=17653272; DOI=10.1371/journal.pone.0000645;
RA   Villard V., Agak G.W., Frank G., Jafarshad A., Servis C., Nebie I.,
RA   Sirima S.B., Felger I., Arevalo-Herrera M., Herrera S., Heitz F.,
RA   Baecker V., Druilhe P., Kajava A.V., Corradin G.;
RT   "Rapid identification of malaria vaccine candidates based on alpha-helical
RT   coiled coil protein motif.";
RL   PLoS ONE 2:E645-E645(2007).
CC   -!- BIOTECHNOLOGY: Possible candidate for an effective malaria vaccine as
CC       determined by epitope response in sera. {ECO:0000269|PubMed:17653272}.
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DR   EMBL; LN999945; CZT98862.1; -; Genomic_DNA.
DR   RefSeq; XP_001347878.2; XM_001347842.2.
DR   AlphaFoldDB; Q8IIG7; -.
DR   SMR; Q8IIG7; -.
DR   BioGRID; 1206149; 1.
DR   IntAct; Q8IIG7; 1.
DR   STRING; 5833.PF11_0207; -.
DR   PRIDE; Q8IIG7; -.
DR   EnsemblProtists; CZT98862; CZT98862; PF3D7_1120000.
DR   GeneID; 810754; -.
DR   KEGG; pfa:PF3D7_1120000; -.
DR   VEuPathDB; PlasmoDB:PF3D7_1120000; -.
DR   HOGENOM; CLU_322253_0_0_1; -.
DR   InParanoid; Q8IIG7; -.
DR   OMA; TKEYVTG; -.
DR   PhylomeDB; Q8IIG7; -.
DR   Proteomes; UP000001450; Chromosome 11.
DR   GO; GO:0005737; C:cytoplasm; NAS:UniProtKB.
DR   GO; GO:0016020; C:membrane; NAS:UniProtKB.
PE   1: Evidence at protein level;
KW   Coiled coil; Merozoite; Reference proteome.
FT   CHAIN           1..1070
FT                   /note="Uncharacterized protein PF3D7_1120000"
FT                   /id="PRO_0000371502"
FT   REGION          66..88
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          355..388
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          423..483
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          667..692
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          735..786
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          475..736
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        751..768
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        769..786
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1070 AA;  128952 MW;  16BADEB4758103E0 CRC64;
     MAKKKKQIHL NIIDFQKYYQ TDDLLLDTSI STEKKTVDNQ KFIRKNRTLE KDEVVQNIDW
     RTFDNEKEKE TNNENTSNVN KIKSPGLEKK NFKKSNDVIT LGARNKNKST NLNADDIDFT
     NLRNKKKEDD IDFTNLRNKK KEDDLDFSNL RNKKKEEEDV DFSNLRNKKK EDDVDFSNVR
     NKKKEDDLDF SNVRNKKKED DVNFSDVRNK KKEDDLDFSN VRNKKKEDDV NFSDVRNKKK
     EDDLDFSNVR NKKKEDDVNF SDVRNKKKED ALDFSNVRNK KKEDDLDFSN VRNKNKEDDM
     DFSNVRNKKK EDDLDFSNVR NKKKEDDLDF SNVRNKKKED DLNFSNVRNK KKEDDLDFSN
     VRNKNKEDDM DFSNVRNKKK EDDMDFSNVR NKKKEDDLDF SNVRNKKKED DLDFSNVRNK
     KKEDDLDFSN LRNKKKEESK ENDTNKSEKP LYLRRLEEYR KKKKLESQAN DTAMKMHEKE
     QIDDIQERKE EIKEEFKEEV KEEIKEIKEE IKEVKEEIKE EIKEEIKEVK EEIKEEIKEE
     IKEVKEEIKE VKEEIKEVKE EIKEVKEEIK EEIKEVKEEI KEEIKEEIKE VKEEIKEEVK
     EEIKEVKEEI KEVKEEIKEE VKEEIKEVKE EIKEVKEEIK EEIKEVKEEI KEEVKEEIKE
     EIKEIKEELK NDISSETTKE EKNTEHKKEE TEKKKFIPKR VIMYQQELKE KEERNLKLLE
     QQRKEREMRL QLIRSKTQGT SSTFIPSAKL KHLESLKEEK KKEVKTNIQP KDNNNNNNNN
     NNNNNNIAVL KNNKNEEQNV IKKKSIFLEI AEKTENAKIV EKTDIEEIAK KKREELYKKQ
     LEKITKKNEE HLKYNNIYKH DVNIIKNFYN EIKDKIIQNY YFNQDDCISL CSILKTDDCN
     YMESHVPFYV VISIFMLSLP QKLQNDDYFK RASNIKNLLI YLKENSKIEN HEDYILNDTL
     KFCDQLKYPH LSEETSLIET IFDTLLYSGV ISKNSFIQWF QDDDSNAELK SKAMLQLIYW
     HKWLTEEEKD QEEEIDELDD TEEKNISDVS DIEKNVPKNF IFKKIKKKLF