ID   YPF13_PLAF7             Reviewed;         989 AA.
AC   Q8IC19;
DT   03-NOV-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   25-MAY-2022, entry version 69.
DE   RecName: Full=Uncharacterized protein PF07_0021 {ECO:0000312|EMBL:CAD50822.1};
GN   ORFNames=PF07_0021;
OS   Plasmodium falciparum (isolate 3D7).
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC   Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX   NCBI_TaxID=36329;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=3D7;
RX   PubMed=12368864; DOI=10.1038/nature01097;
RA   Gardner M.J., Hall N., Fung E., White O., Berriman M., Hyman R.W.,
RA   Carlton J.M., Pain A., Nelson K.E., Bowman S., Paulsen I.T., James K.D.,
RA   Eisen J.A., Rutherford K.M., Salzberg S.L., Craig A., Kyes S., Chan M.-S.,
RA   Nene V., Shallom S.J., Suh B., Peterson J., Angiuoli S., Pertea M.,
RA   Allen J., Selengut J., Haft D., Mather M.W., Vaidya A.B., Martin D.M.A.,
RA   Fairlamb A.H., Fraunholz M.J., Roos D.S., Ralph S.A., McFadden G.I.,
RA   Cummings L.M., Subramanian G.M., Mungall C., Venter J.C., Carucci D.J.,
RA   Hoffman S.L., Newbold C., Davis R.W., Fraser C.M., Barrell B.G.;
RT   "Genome sequence of the human malaria parasite Plasmodium falciparum.";
RL   Nature 419:498-511(2002).
RN   [2] {ECO:0000312|EMBL:CAD50822.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=3D7;
RX   PubMed=12368867; DOI=10.1038/nature01095;
RA   Hall N., Pain A., Berriman M., Churcher C.M., Harris B., Harris D.,
RA   Mungall K.L., Bowman S., Atkin R., Baker S., Barron A., Brooks K.,
RA   Buckee C.O., Burrows C., Cherevach I., Chillingworth C., Chillingworth T.,
RA   Christodoulou Z., Clark L., Clark R., Corton C., Cronin A., Davies R.M.,
RA   Davis P., Dear P., Dearden F., Doggett J., Feltwell T., Goble A.,
RA   Goodhead I., Gwilliam R., Hamlin N., Hance Z., Harper D., Hauser H.,
RA   Hornsby T., Holroyd S., Horrocks P., Humphray S., Jagels K., James K.D.,
RA   Johnson D., Kerhornou A., Knights A., Konfortov B., Kyes S., Larke N.,
RA   Lawson D., Lennard N., Line A., Maddison M., Mclean J., Mooney P.,
RA   Moule S., Murphy L., Oliver K., Ormond D., Price C., Quail M.A.,
RA   Rabbinowitsch E., Rajandream M.A., Rutter S., Rutherford K.M., Sanders M.,
RA   Simmonds M., Seeger K., Sharp S., Smith R., Squares R., Squares S.,
RA   Stevens K., Taylor K., Tivey A., Unwin L., Whitehead S., Woodward J.R.,
RA   Sulston J.E., Craig A., Newbold C., Barrell B.G.;
RT   "Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13.";
RL   Nature 419:527-531(2002).
RN   [3] {ECO:0000305}
RP   SYNTHESIS OF 65-112, AND POSSIBLE CANDIDATE MALARIA EPITOPE.
RX   PubMed=17653272; DOI=10.1371/journal.pone.0000645;
RA   Villard V., Agak G.W., Frank G., Jafarshad A., Servis C., Nebie I.,
RA   Sirima S.B., Felger I., Arevalo-Herrera M., Herrera S., Heitz F.,
RA   Baecker V., Druilhe P., Kajava A.V., Corradin G.;
RT   "Rapid identification of malaria vaccine candidates based on alpha-helical
RT   coiled coil protein motif.";
RL   PLoS ONE 2:E645-E645(2007).
CC   -!- BIOTECHNOLOGY: Possible candidate for an effective malaria vaccine as
CC       determined by epitope response in sera. {ECO:0000269|PubMed:17653272}.
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DR   EMBL; AL844506; CAD50822.1; -; Genomic_DNA.
DR   RefSeq; XP_001348984.1; XM_001348948.1.
DR   AlphaFoldDB; Q8IC19; -.
DR   BioGRID; 1209915; 1.
DR   STRING; 5833.PF07_0021; -.
DR   PRIDE; Q8IC19; -.
DR   EnsemblProtists; CAD50822; CAD50822; PF3D7_0705100.
DR   GeneID; 2655057; -.
DR   KEGG; pfa:PF3D7_0705100; -.
DR   VEuPathDB; PlasmoDB:PF3D7_0705100; -.
DR   HOGENOM; CLU_340252_0_0_1; -.
DR   InParanoid; Q8IC19; -.
DR   OMA; YMLCYDK; -.
DR   Proteomes; UP000001450; Chromosome 7.
PE   1: Evidence at protein level;
KW   Coiled coil; Merozoite; Reference proteome.
FT   CHAIN           1..989
FT                   /note="Uncharacterized protein PF07_0021"
FT                   /id="PRO_0000388766"
FT   REGION          1..20
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          538..654
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   989 AA;  118345 MW;  00D9D7137B46A26E CRC64;
     MSIHISDEEA EGRNFDQKNK ISSHEKNQII NNFIINYNMK KENDINQINE INEINGTNQS
     VNRKKNMDTV YKNIINMSNN MTQMYNSMNN MSHNIINASH DMMDASGNIN SHINDTNNQT
     NYMMSSHINN IENETNNMMT SQINILNQNP YIRTRHINTD DMNQLDNISS QTSPNINNNC
     TTKYNDINNS YVNVLYFRKL KLNKKLFEKL KNKNIVIYLK YKDSTCTSEK IEITDPEINN
     LYLCFLVTEP FLENEKKIVK IYIKCFKDGK YKILSFGFVE LNFVDFSEKF YRKKSYMLCY
     DKKNNKYIFG YFILILANQI KWKVCDNKVF YEYIKKSYFV SNRKNYDQQI FYICKKIQKK
     LLQSYYTNTT NPYRNLHNQA LLKHFSVTHS CPGTFSLNTT KNKNSYDHYK NENDIETKNQ
     NYLYDIKKSK SLIPLNLMKN DILYPQLSHD NYKIKSMIHN SYNIANYTTY KEKWGHENLY
     EMKKNNSIQE KNDMSMNFKG IEKGTANFLL NHEKNEQIKE YKDKYQKNNT YQSEQNCDIK
     QYYEKNEQIN EYKDKYQKNN TYQREQNCDI KQYYEKNEQI NEYKNKYQKN NTYQSEQNCD
     IKQYYEKNEQ INEYKDKYQK NNTYQSEQNC DINTLDIKQV TNQIEDIKSE QNNVYSNITE
     NPFFNTDEYE INHSFNNIHE YNDTDKNEYI KNNVDNEEEE SIEKNIFDNI ICEKLQNILN
     NGIESFIQEI QFILEHLKKK IIKKNDYFLN QLKNDHIYEY NPEMNSQNIN EHNEEYTLED
     YIIKSKYNNN VKNDIMSILQ NCLNTTLLYI KCILKDTNIN KQEKNIFAAY ENIVKNIKQA
     VSHYVIENET FNHDILNTDI LTQNKNISLH TSLSKSRNSI TNKNCKLTKI EIQENEMESD
     KEKYLGHYNK TSNVLKEKNN MNSYINSDET LSSSSLSTCS NESHKKIKLM SRQIEHFKMN
     SYINENISSA FKYYEHKWKN KLAKIGAYI