YPF15_PLAF7
ID YPF15_PLAF7 Reviewed; 1033 AA.
AC Q8IBB8;
DT 03-NOV-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 25-MAY-2022, entry version 74.
DE RecName: Full=Uncharacterized protein MAL8P1.12 {ECO:0000312|EMBL:CAD51088.1};
GN ORFNames=MAL8P1.12;
OS Plasmodium falciparum (isolate 3D7).
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Laverania).
OX NCBI_TaxID=36329;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=3D7;
RX PubMed=12368864; DOI=10.1038/nature01097;
RA Gardner M.J., Hall N., Fung E., White O., Berriman M., Hyman R.W.,
RA Carlton J.M., Pain A., Nelson K.E., Bowman S., Paulsen I.T., James K.D.,
RA Eisen J.A., Rutherford K.M., Salzberg S.L., Craig A., Kyes S., Chan M.-S.,
RA Nene V., Shallom S.J., Suh B., Peterson J., Angiuoli S., Pertea M.,
RA Allen J., Selengut J., Haft D., Mather M.W., Vaidya A.B., Martin D.M.A.,
RA Fairlamb A.H., Fraunholz M.J., Roos D.S., Ralph S.A., McFadden G.I.,
RA Cummings L.M., Subramanian G.M., Mungall C., Venter J.C., Carucci D.J.,
RA Hoffman S.L., Newbold C., Davis R.W., Fraser C.M., Barrell B.G.;
RT "Genome sequence of the human malaria parasite Plasmodium falciparum.";
RL Nature 419:498-511(2002).
RN [2] {ECO:0000312|EMBL:CAD51088.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=3D7;
RX PubMed=12368867; DOI=10.1038/nature01095;
RA Hall N., Pain A., Berriman M., Churcher C.M., Harris B., Harris D.,
RA Mungall K.L., Bowman S., Atkin R., Baker S., Barron A., Brooks K.,
RA Buckee C.O., Burrows C., Cherevach I., Chillingworth C., Chillingworth T.,
RA Christodoulou Z., Clark L., Clark R., Corton C., Cronin A., Davies R.M.,
RA Davis P., Dear P., Dearden F., Doggett J., Feltwell T., Goble A.,
RA Goodhead I., Gwilliam R., Hamlin N., Hance Z., Harper D., Hauser H.,
RA Hornsby T., Holroyd S., Horrocks P., Humphray S., Jagels K., James K.D.,
RA Johnson D., Kerhornou A., Knights A., Konfortov B., Kyes S., Larke N.,
RA Lawson D., Lennard N., Line A., Maddison M., Mclean J., Mooney P.,
RA Moule S., Murphy L., Oliver K., Ormond D., Price C., Quail M.A.,
RA Rabbinowitsch E., Rajandream M.A., Rutter S., Rutherford K.M., Sanders M.,
RA Simmonds M., Seeger K., Sharp S., Smith R., Squares R., Squares S.,
RA Stevens K., Taylor K., Tivey A., Unwin L., Whitehead S., Woodward J.R.,
RA Sulston J.E., Craig A., Newbold C., Barrell B.G.;
RT "Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13.";
RL Nature 419:527-531(2002).
RN [3] {ECO:0000305}
RP SYNTHESIS OF 860-914, AND POSSIBLE CANDIDATE MALARIA EPITOPE.
RX PubMed=17653272; DOI=10.1371/journal.pone.0000645;
RA Villard V., Agak G.W., Frank G., Jafarshad A., Servis C., Nebie I.,
RA Sirima S.B., Felger I., Arevalo-Herrera M., Herrera S., Heitz F.,
RA Baecker V., Druilhe P., Kajava A.V., Corradin G.;
RT "Rapid identification of malaria vaccine candidates based on alpha-helical
RT coiled coil protein motif.";
RL PLoS ONE 2:E645-E645(2007).
CC -!- BIOTECHNOLOGY: Possible candidate for an effective malaria vaccine as
CC determined by epitope response in sera. {ECO:0000269|PubMed:17653272}.
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DR EMBL; AL844507; CAD51088.1; -; Genomic_DNA.
DR RefSeq; XP_001349239.1; XM_001349203.1.
DR AlphaFoldDB; Q8IBB8; -.
DR SMR; Q8IBB8; -.
DR BioGRID; 1210092; 1.
DR IntAct; Q8IBB8; 1.
DR STRING; 5833.MAL8P1.12; -.
DR PRIDE; Q8IBB8; -.
DR EnsemblProtists; CAD51088; CAD51088; PF3D7_0828700.
DR GeneID; 2655240; -.
DR KEGG; pfa:PF3D7_0828700; -.
DR VEuPathDB; PlasmoDB:PF3D7_0828700; -.
DR HOGENOM; CLU_293979_0_0_1; -.
DR InParanoid; Q8IBB8; -.
DR OMA; TQIKIKQ; -.
DR PhylomeDB; Q8IBB8; -.
DR Proteomes; UP000001450; Chromosome 8.
DR GO; GO:0005930; C:axoneme; IBA:GO_Central.
DR GO; GO:0005737; C:cytoplasm; NAS:UniProtKB.
DR GO; GO:0003341; P:cilium movement; IBA:GO_Central.
DR GO; GO:0060285; P:cilium-dependent cell motility; IBA:GO_Central.
DR GO; GO:0036159; P:inner dynein arm assembly; IBA:GO_Central.
DR InterPro; IPR033290; CCDC39.
DR PANTHER; PTHR18962; PTHR18962; 1.
PE 1: Evidence at protein level;
KW Coiled coil; Merozoite; Reference proteome.
FT CHAIN 1..1033
FT /note="Uncharacterized protein MAL8P1.12"
FT /id="PRO_0000388768"
FT COILED 212..326
FT /evidence="ECO:0000255"
FT COILED 405..582
FT /evidence="ECO:0000255"
FT COILED 615..771
FT /evidence="ECO:0000255"
FT COILED 797..1019
FT /evidence="ECO:0000255"
SQ SEQUENCE 1033 AA; 123778 MW; 7BF0F2F91F2182FE CRC64;
MSEESFDDTN KAFENEKDII LEKIVKDENN LNNCSNMINM DDVENMKKEL YVLHKKDEEI
ENNVDCFSGD KYNVENVINL KKKKKKDEDT DSSYYKTTLD EVYDTSDIST DEMLSNYSSS
EDNNNIEMNI INDFYLKDDN TYCLEWNSDI INVLSEEIKE KEKLLEDENK DICNMKSRFL
KLEKYVNIKK KKIINIKKNI EEKRKIEFDE KEIFKCLQIK NDFLKKENKK IELEREKNNK
KIIETQNNIT TCQKNIDDIK KELILKENEL NDFINKIKII QQEEYEIEKI KLSKDKEIQN
VSYNLEKYNN EKIQQDKKYE QVKMNNMKFD IELKSIIQEY YDIKKDIKNI SNKYICIMDM
IKCRDKTIYK FEKDYTKTIH KEKQLQNKCL HKQNLINTQK DKNIILNNQI KKIQFDINKI
RKELNDKQMS YDKTIIDRDH LNKEYEYEIV EIKEKLQEEK KSLENTLQHL NETYITMSTN
YEESKNEYEK EQVNNIEKND LIKSSEQILV QLQNKLQKLL DEIKSLDLEK FQLTQTLQVI
KNDYITLEAD VLGTQIKIKQ IKSNIKKTEK ELERQKEMLY KFDFQTQVLT KKINMISGIS
TFEKKKENQK KIILLEKELY KNEDIYNTLN NEMKRINIEI KNIKLYQNEL QEQKMNYKNL
YEKLQLEIKS LESTINNEIK EKENIMLIEL NLKIELDKLK STFSKHVDNL NICKKEKKEN
MNNAKLSEQD INAHMESLKV IIKNINDEIH KLNIQLYEKK NKSNNLQLKL NSIIICNQKN
KDQKDICPNE NQHIYYKMKI DQDIINLKEQ LKKINEQIDK ENIETKNFQR TLDDIIQTNK
EFNDNIKSID PQYKILLKKK NKLNKKWEQI NDHINNLETN INDYNKKIKE GDSQLNNIQL
QCENIEQKIN KIKESNLKVE NNINDLFIKI ERASNQLKKN LAPTTNMMKL KNKQIKDDEN
NLSNNNNNNN NNNNNINVNV NVNCEPVPLE KHIFKQIQME SLKEKLSLLM ECFKNNIDNV
IMKEVFNLIE TAE
