ID   YPH1_METEX              Reviewed;         276 AA.
AC   P52071;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   03-AUG-2022, entry version 75.
DE   RecName: Full=Uncharacterized protein in phaC 3'region;
DE   AltName: Full=ORF1;
DE   Flags: Fragment;
OS   Methylorubrum extorquens (Methylobacterium dichloromethanicum)
OS   (Methylobacterium extorquens).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Methylobacteriaceae; Methylorubrum.
OX   NCBI_TaxID=408;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=IBT 6;
RX   PubMed=7763712; DOI=10.1007/bf00192084;
RA   Valentin H.E., Steinbuechel A.;
RT   "Cloning and characterization of the Methylobacterium extorquens
RT   polyhydroxyalkanoic-acid-synthase structural gene.";
RL   Appl. Microbiol. Biotechnol. 39:309-317(1993).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the monovalent cation:proton antiporter 2 (CPA2)
CC       transporter (TC 2.A.37) family. {ECO:0000305}.
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DR   EMBL; L07893; AAA72331.1; -; Genomic_DNA.
DR   AlphaFoldDB; P52071; -.
DR   SMR; P52071; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015299; F:solute:proton antiporter activity; IEA:InterPro.
DR   GO; GO:0006812; P:cation transport; IEA:InterPro.
DR   Gene3D; 1.20.1530.20; -; 1.
DR   InterPro; IPR006153; Cation/H_exchanger.
DR   InterPro; IPR038770; Na+/solute_symporter_sf.
DR   Pfam; PF00999; Na_H_Exchanger; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..>276
FT                   /note="Uncharacterized protein in phaC 3'region"
FT                   /id="PRO_0000196617"
FT   TRANSMEM        5..25
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        32..52
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        64..84
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        104..124
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        149..169
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        193..213
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        244..264
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   NON_TER         276
SQ   SEQUENCE   276 AA;  27996 MW;  D69A37BB6EEE6C8C CRC64;
     MQHATDLISI IALGLVCAFI GGMLAQRMRL PPLVGYLVAG IAIGPFTPGF VGDPALASQL
     AELGVILLMF GVGLHFSIGD LLAVRTIALP GAIVQITVAT AMGAGLAWGF GWGAGAGLVF
     GLALSVASTV VLLRALEGQG LLDSDKGRIA VGWLIVEDLA MVVALVLLPA LAPSLGGEAM
     QAAGHHGPPE HGLWVTLGLT LAKVGVFVAV MLVGGRRLIP YLLGLAARTG SRELFTLAVL
     ASAVGIAFAS SELFGVSFAL GAFFAGMVLA ESDLSH