ID   YPI2_PICST              Reviewed;         192 AA.
AC   A3GGT2;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   19-JAN-2010, sequence version 2.
DT   25-MAY-2022, entry version 63.
DE   RecName: Full=Type 1 phosphatases regulator YPI2;
GN   Name=YPI2; ORFNames=PICST_28729;
OS   Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL
OS   Y-11545) (Yeast) (Pichia stipitis).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Scheffersomyces.
OX   NCBI_TaxID=322104;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545;
RX   PubMed=17334359; DOI=10.1038/nbt1290;
RA   Jeffries T.W., Grigoriev I.V., Grimwood J., Laplaza J.M., Aerts A.,
RA   Salamov A., Schmutz J., Lindquist E., Dehal P., Shapiro H., Jin Y.-S.,
RA   Passoth V., Richardson P.M.;
RT   "Genome sequence of the lignocellulose-bioconverting and xylose-fermenting
RT   yeast Pichia stipitis.";
RL   Nat. Biotechnol. 25:319-326(2007).
CC   -!- FUNCTION: Regulator of type 1 phosphatases which maintains protein
CC       phosphatase activity under strict control. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the YPI1 family. {ECO:0000305}.
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DR   EMBL; AAVQ01000001; EAZ63588.2; -; Genomic_DNA.
DR   RefSeq; XP_001387611.2; XM_001387574.1.
DR   AlphaFoldDB; A3GGT2; -.
DR   STRING; 4924.XP_001387611.2; -.
DR   EnsemblFungi; EAZ63588; EAZ63588; PICST_28729.
DR   GeneID; 4851481; -.
DR   KEGG; pic:PICST_28729; -.
DR   eggNOG; KOG4102; Eukaryota.
DR   HOGENOM; CLU_098333_3_0_1; -.
DR   InParanoid; A3GGT2; -.
DR   OMA; CEYGHIH; -.
DR   OrthoDB; 1599272at2759; -.
DR   Proteomes; UP000002258; Chromosome 1.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0004865; F:protein serine/threonine phosphatase inhibitor activity; IEA:InterPro.
DR   GO; GO:0032515; P:negative regulation of phosphoprotein phosphatase activity; IEA:InterPro.
DR   InterPro; IPR011107; PPI_Ypi1.
DR   PANTHER; PTHR20835; PTHR20835; 1.
DR   Pfam; PF07491; PPI_Ypi1; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome.
FT   CHAIN           1..192
FT                   /note="Type 1 phosphatases regulator YPI2"
FT                   /id="PRO_0000333489"
FT   REGION          1..53
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          65..192
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..20
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        23..53
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        81..128
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        129..150
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        173..192
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   192 AA;  22134 MW;  41205B857A718A62 CRC64;
     MLQRNRIQTS SSTQTETTPP ILRLRRPETR QKEDSKVKWT EDVIDNEHMG KHKSKVCCIF
     HPHREFGQSS DESSDSSSDS SDDSDYERNN DFDQNHRHSH NFDDINSDNS HSHSHGHNFD
     DKDDISNSSN NQDKGNTGMS KPSSSSPDNL VCEYGHIHKR NKKVRKPKRS SSPNAYERQP
     NYRNKSVVPV QK