ID   YPLP_BACSU              Reviewed;         331 AA.
AC   P54156;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   03-AUG-2022, entry version 126.
DE   RecName: Full=Putative sigma L-dependent transcriptional regulator YplP;
GN   Name=yplP; OrderedLocusNames=BSU21780;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168 / Marburg / ATCC 6051 / DSM 10 / JCM 1465 / NBRC 13719 / NCIMB
RC   3610 / NRRL NRS-744 / VKM B-501;
RX   PubMed=8969496; DOI=10.1099/13500872-142-11-3005;
RA   Capuano V., Galleron N., Pujic P., Sorokin A., Ehrlich S.D.;
RT   "Organization of the Bacillus subtilis 168 chromosome between kdg and the
RT   attachment site of the SP beta prophage: use of long accurate PCR and yeast
RT   artificial chromosomes for sequencing.";
RL   Microbiology 142:3005-3015(1996).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
RN   [3]
RP   FUNCTION, INDUCTION BY COLD SHOCK, AND DISRUPTION PHENOTYPE.
RC   STRAIN=168 / JH642;
RX   PubMed=12399512; DOI=10.1128/jb.184.22.6395-6402.2002;
RA   Beckering C.L., Steil L., Weber M.H.W., Voelker U., Marahiel M.A.;
RT   "Genomewide transcriptional analysis of the cold shock response in Bacillus
RT   subtilis.";
RL   J. Bacteriol. 184:6395-6402(2002).
CC   -!- FUNCTION: May play a role in cold adaptation.
CC       {ECO:0000305|PubMed:12399512}.
CC   -!- INDUCTION: 8-fold induction by growth at 15 degrees Celsius.
CC       {ECO:0000269|PubMed:12399512}.
CC   -!- DISRUPTION PHENOTYPE: Cells grow much more slowly at 15 degrees
CC       Celsius. {ECO:0000269|PubMed:12399512}.
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DR   EMBL; L77246; AAA96638.1; -; Genomic_DNA.
DR   EMBL; AL009126; CAB14096.1; -; Genomic_DNA.
DR   PIR; C69938; C69938.
DR   RefSeq; NP_390061.1; NC_000964.3.
DR   RefSeq; WP_004399025.1; NZ_JNCM01000036.1.
DR   AlphaFoldDB; P54156; -.
DR   SMR; P54156; -.
DR   STRING; 224308.BSU21780; -.
DR   PaxDb; P54156; -.
DR   PRIDE; P54156; -.
DR   EnsemblBacteria; CAB14096; CAB14096; BSU_21780.
DR   GeneID; 939094; -.
DR   KEGG; bsu:BSU21780; -.
DR   PATRIC; fig|224308.179.peg.2380; -.
DR   eggNOG; COG1221; Bacteria.
DR   InParanoid; P54156; -.
DR   OMA; HIDPSVY; -.
DR   PhylomeDB; P54156; -.
DR   BioCyc; BSUB:BSU21780-MON; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0000160; P:phosphorelay signal transduction system; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR013668; RNase_R_HTH_12.
DR   InterPro; IPR002078; Sigma_54_int.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   Pfam; PF08461; HTH_12; 1.
DR   Pfam; PF00158; Sigma54_activat; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS50045; SIGMA54_INTERACT_4; 1.
PE   2: Evidence at transcript level;
KW   ATP-binding; Nucleotide-binding; Reference proteome;
KW   Two-component regulatory system.
FT   CHAIN           1..331
FT                   /note="Putative sigma L-dependent transcriptional regulator
FT                   YplP"
FT                   /id="PRO_0000081385"
FT   DOMAIN          12..213
FT                   /note="Sigma-54 factor interaction"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00193"
FT   BINDING         95..104
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00193"
SQ   SEQUENCE   331 AA;  37210 MW;  D6AFD728B3E22310 CRC64;
     MNSAPKLNTF QHLIGEHQTF LEAKRIAKQF SLSELPVLIT GKIGTGKNHF AHAIHLESSR
     SNEPFISVNC STHSEETLIH ELFGPNGNTG VFQKAVRGTL FLDDVWRMPA SVQAQLLKAL
     DSDTEKPRMI CASADRSVEH TFRQDLFYRL NILTLTLPEL SERKSDIPLL TQHFLSNSGQ
     QLLIDPSVFP VLEKHAFEGN VRELKNAADY MAAVSSGGTI QPYDLPPYIR GTIDGKTSKK
     KAKLLTLMEK AEFLFILETI KVLNEKGEPA SRRIISEHSK NTQTSLTPQQ VRSRLDYLEK
     KDYVTKSRGR AGTKITFEGL SFIETLKNQM I