ID   YPP1_CANGA              Reviewed;         788 AA.
AC   Q6FNC6;
DT   23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 86.
DE   RecName: Full=Cargo-transport protein YPP1;
GN   Name=YPP1; OrderedLocusNames=CAGL0K01001g;
OS   Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL
OS   Y-65) (Yeast) (Torulopsis glabrata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC   Nakaseomyces/Candida clade.
OX   NCBI_TaxID=284593;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Involved in endocytosis. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasmic granule {ECO:0000250}. Cell membrane
CC       {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic
CC       side {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the YPP1 family. {ECO:0000305}.
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DR   EMBL; CR380957; CAG61229.1; -; Genomic_DNA.
DR   RefSeq; XP_448268.1; XM_448268.1.
DR   AlphaFoldDB; Q6FNC6; -.
DR   SMR; Q6FNC6; -.
DR   STRING; 5478.XP_448268.1; -.
DR   PRIDE; Q6FNC6; -.
DR   EnsemblFungi; CAG61229; CAG61229; CAGL0K01001g.
DR   GeneID; 2890152; -.
DR   KEGG; cgr:CAGL0K01001g; -.
DR   CGD; CAL0134131; CAGL0K01001g.
DR   VEuPathDB; FungiDB:CAGL0K01001g; -.
DR   eggNOG; ENOG502QV6B; Eukaryota.
DR   HOGENOM; CLU_019616_0_0_1; -.
DR   InParanoid; Q6FNC6; -.
DR   OMA; VSFKIVC; -.
DR   Proteomes; UP000002428; Chromosome K.
DR   GO; GO:0030479; C:actin cortical patch; IEA:EnsemblFungi.
DR   GO; GO:0005829; C:cytosol; IEA:EnsemblFungi.
DR   GO; GO:0005768; C:endosome; IEA:EnsemblFungi.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0072659; P:protein localization to plasma membrane; IEA:EnsemblFungi.
DR   GO; GO:0006623; P:protein targeting to vacuole; IEA:EnsemblFungi.
DR   GO; GO:0006898; P:receptor-mediated endocytosis; IEA:EnsemblFungi.
DR   GO; GO:0019236; P:response to pheromone; IEA:EnsemblFungi.
DR   Gene3D; 1.25.40.10; -; 2.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   SUPFAM; SSF48452; SSF48452; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Endocytosis; Membrane; Reference proteome.
FT   CHAIN           1..788
FT                   /note="Cargo-transport protein YPP1"
FT                   /id="PRO_0000308807"
SQ   SEQUENCE   788 AA;  91140 MW;  5962541E80E73AE9 CRC64;
     MFIRDAVLQA LEARLLGASE FHSTCNALDR ALVVQFRLQY HTGGDSVITP ATGKVLFGDI
     DKVEMLSRRF PLDKPLLDLI NKILGNCAGI IHFSIGEFED AKVRLQQARD IKLDKTFDVY
     DMYLGLENLY YTACLRQDEQ QISDCLYDHL FDTLSFVPSA SEALTHQCLW KIAKRLKGHN
     NLANLIKIWP ENNRALVFLI SIIASDNGAY TEFSKDNDEM ILKYGMNLVE KIKFPKASEN
     NNYHLEQFML FLQVYFKNIV PDQAASTEWY NFILKAMSKT FQSINVAHTA LFVMKKIGSD
     NEKGKINGTL LRKEALLNFV NFIRYSNKEF KLNKNYNDII SLLVCYNFVI NEFTKKDNID
     NLFDYDKSLD ELLSLLVFFY KEYNIPLSEK KQSLDILENP IRLAFPPHVA NTLSRSWLTL
     YNYHSTSLSA LLSFDLLAFL ANCVPISRSM DEGLFISTVF QYALTLAKQR DVETAIKVLE
     KLILERHPNC YKAWHLMALC HSTKENKETA YKIVCSVLEA MNENMKDLTF EEKFQYIYMK
     ITQLRLIQDM FGTDETLELI PELFELYNTL FLGGANQKKV TINGVYDLDM TLQDIWLYVC
     SLYMKTPSTD NLQEAETAMD EAMALEKDHW KGRYLPLRAK LNILKQQNKQ ALLDIEKAID
     LDNSNIDAIL CFAELIFDVE KKSEEDLTDE YYKLVPIEGI KECSKNQSEN EDRLFFNATD
     RSAATARLKL LLDSAVAESI EGYYTPEVWW SLSQIHEQFA TKDYKLSLMK CIKFEELRPI
     AQFENCNY