ID   YPP1_KLULA              Reviewed;         719 AA.
AC   Q6CJ29;
DT   23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 87.
DE   RecName: Full=Cargo-transport protein YPP1;
GN   Name=YPP1; OrderedLocusNames=KLLA0F21956g;
OS   Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 /
OS   NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX   NCBI_TaxID=284590;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Involved in endocytosis. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasmic granule {ECO:0000250}. Cell membrane
CC       {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic
CC       side {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the YPP1 family. {ECO:0000305}.
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DR   EMBL; CR382126; CAG98768.1; -; Genomic_DNA.
DR   RefSeq; XP_456060.1; XM_456060.1.
DR   AlphaFoldDB; Q6CJ29; -.
DR   SMR; Q6CJ29; -.
DR   STRING; 28985.XP_456060.1; -.
DR   EnsemblFungi; CAG98768; CAG98768; KLLA0_F21956g.
DR   GeneID; 2895421; -.
DR   KEGG; kla:KLLA0_F21956g; -.
DR   eggNOG; ENOG502QV6B; Eukaryota.
DR   HOGENOM; CLU_019616_0_0_1; -.
DR   InParanoid; Q6CJ29; -.
DR   OMA; VSFKIVC; -.
DR   Proteomes; UP000000598; Chromosome F.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.40.10; -; 1.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   SUPFAM; SSF48452; SSF48452; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Endocytosis; Membrane; Reference proteome.
FT   CHAIN           1..719
FT                   /note="Cargo-transport protein YPP1"
FT                   /id="PRO_0000308808"
SQ   SEQUENCE   719 AA;  82965 MW;  A5F1D1C5684AAA34 CRC64;
     MTRGYIDDSV NHALDSRLIG SSVFQSSDAL LDQLLSLHYR AHYHINISTK TKFSALSALL
     SEVEKLPVLK DELHCAIADN IYGIVFCELD EKEKGLQYVS KKLGSVNGYD RFGRMLDLER
     LFYKGNVDLA EFSSESWTIP KYSDGLTWHY LQAIIKGLDL SHFKPKTPFQ WMLLTLNGSA
     TDSNLLSYSH SLLKKSRFPN ADESNNFELE QFHMVLQEHL KINNLNVKKE WEQFIIDSME
     KSFQSISVAK SAMLFYRKVD LKRSILNFTN LVNYSNKYYE LNKRYPDLLD LVSSYQFILS
     TCKTPFEPFF MPANVSSDFL KLLERIHNKY SIPIIEKQKA LEGSSDVLDL CLASSTASVL
     SSSWETLYET SASSLPALVD HSQIFYLSNS LQTSLNASVS LKFKFAYHLA TLRQIDQCIA
     YLKKQILTLH PEHFASWHLL ALCESCINED LQVSFKIINS VIQSMCELFD EGRQFTIDEK
     WQFIHIKLTQ LQLVRDMFAL EDALEILPEV FELYQRLFSD ASEPLGPQIN QSNDYLLQKI
     WLFALELYLE NDDIENVKAA LDEFKNVTSK YVNLNHNLAQ GFVLYTHGHS EKATAEFEKV
     LHYDSTSVEA LIGLAKIVLP DEEANLDTDL KHNSKINQKE LHRNSATSLE TSSAVARLKF
     LFEELVDKSI EGYQTSAVWW YLSKIYEIYS DSTRQQEALW RCIKYEELQP VREFKFCNF