YPR71_YEAST
ID YPR71_YEAST Reviewed; 211 AA.
AC Q12346; D6W475;
DT 03-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 03-AUG-2022, entry version 128.
DE RecName: Full=Uncharacterized membrane protein YPR071W;
GN OrderedLocusNames=YPR071W; ORFNames=YP9499.26;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=9169875;
RA Bussey H., Storms R.K., Ahmed A., Albermann K., Allen E., Ansorge W.,
RA Araujo R., Aparicio A., Barrell B.G., Badcock K., Benes V., Botstein D.,
RA Bowman S., Brueckner M., Carpenter J., Cherry J.M., Chung E.,
RA Churcher C.M., Coster F., Davis K., Davis R.W., Dietrich F.S., Delius H.,
RA DiPaolo T., Dubois E., Duesterhoeft A., Duncan M., Floeth M., Fortin N.,
RA Friesen J.D., Fritz C., Goffeau A., Hall J., Hebling U., Heumann K.,
RA Hilbert H., Hillier L.W., Hunicke-Smith S., Hyman R.W., Johnston M.,
RA Kalman S., Kleine K., Komp C., Kurdi O., Lashkari D., Lew H., Lin A.,
RA Lin D., Louis E.J., Marathe R., Messenguy F., Mewes H.-W., Mirtipati S.,
RA Moestl D., Mueller-Auer S., Namath A., Nentwich U., Oefner P., Pearson D.,
RA Petel F.X., Pohl T.M., Purnelle B., Rajandream M.A., Rechmann S.,
RA Rieger M., Riles L., Roberts D., Schaefer M., Scharfe M., Scherens B.,
RA Schramm S., Schroeder M., Sdicu A.-M., Tettelin H., Urrestarazu L.A.,
RA Ushinsky S., Vierendeels F., Vissers S., Voss H., Walsh S.V., Wambutt R.,
RA Wang Y., Wedler E., Wedler H., Winnett E., Zhong W.-W., Zollner A.,
RA Vo D.H., Hani J.;
RT "The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI.";
RL Nature 387:103-105(1997).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [3]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=14562095; DOI=10.1038/nature02026;
RA Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W.,
RA Weissman J.S., O'Shea E.K.;
RT "Global analysis of protein localization in budding yeast.";
RL Nature 425:686-691(2003).
RN [4]
RP TOPOLOGY [LARGE SCALE ANALYSIS].
RC STRAIN=ATCC 208353 / W303-1A;
RX PubMed=16847258; DOI=10.1073/pnas.0604075103;
RA Kim H., Melen K., Oesterberg M., von Heijne G.;
RT "A global topology map of the Saccharomyces cerevisiae membrane proteome.";
RL Proc. Natl. Acad. Sci. U.S.A. 103:11142-11147(2006).
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000269|PubMed:14562095}; Multi-pass membrane protein
CC {ECO:0000269|PubMed:14562095}.
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DR EMBL; Z71255; CAA94979.1; -; Genomic_DNA.
DR EMBL; Z49219; CAA89188.1; -; Genomic_DNA.
DR EMBL; U51033; AAB68122.1; -; Genomic_DNA.
DR EMBL; BK006949; DAA11491.1; -; Genomic_DNA.
DR PIR; S54092; S54092.
DR RefSeq; NP_015396.1; NM_001184168.1.
DR AlphaFoldDB; Q12346; -.
DR BioGRID; 36243; 50.
DR DIP; DIP-3892N; -.
DR IntAct; Q12346; 5.
DR MINT; Q12346; -.
DR STRING; 4932.YPR071W; -.
DR PaxDb; Q12346; -.
DR PRIDE; Q12346; -.
DR EnsemblFungi; YPR071W_mRNA; YPR071W; YPR071W.
DR GeneID; 856184; -.
DR KEGG; sce:YPR071W; -.
DR SGD; S000006275; YPR071W.
DR VEuPathDB; FungiDB:YPR071W; -.
DR GeneTree; ENSGT00940000181333; -.
DR HOGENOM; CLU_1338184_0_0_1; -.
DR OMA; TEMSRRX; -.
DR BioCyc; YEAST:G3O-34218-MON; -.
DR PRO; PR:Q12346; -.
DR Proteomes; UP000002311; Chromosome XVI.
DR RNAct; Q12346; protein.
DR GO; GO:0071944; C:cell periphery; HDA:SGD.
DR GO; GO:0005783; C:endoplasmic reticulum; HDA:SGD.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR InterPro; IPR031427; DUF4668.
DR Pfam; PF15701; DUF4668; 1.
PE 1: Evidence at protein level;
KW Endoplasmic reticulum; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..211
FT /note="Uncharacterized membrane protein YPR071W"
FT /id="PRO_0000252276"
FT TOPO_DOM 1..33
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 34..54
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 55..58
FT /note="Lumenal"
FT /evidence="ECO:0000255"
FT TRANSMEM 59..79
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 80..116
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 117..137
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 138..162
FT /note="Lumenal"
FT /evidence="ECO:0000255"
FT TRANSMEM 163..183
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 184..211
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
SQ SEQUENCE 211 AA; 24606 MW; 975803A6E2AB773A CRC64;
MQNGTEDKSN IPARSNDDVL PPLAVRLTMK VMRLIFIGKM FAYSFVPFPP FKLLTFDNTV
GWFVAYSAIV SIWGFAVWME RGYRHKINLL PPRCTKIRCS RCNTRIRSPN WFKYKNWLYF
FLLYVSLTTS NLIIQLASFM TEMSRRGISV PGTKDPGKRD YLGLIIPMRF IGAFIHYMTA
NLFKEYYLHN GPLEKNDRPS TDEKTSENET L