ID   YPT3_NICPL              Reviewed;         218 AA.
AC   Q01111;
DT   01-APR-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-APR-1993, sequence version 1.
DT   03-AUG-2022, entry version 103.
DE   RecName: Full=Ras-related protein YPT3;
GN   Name=YPT3;
OS   Nicotiana plumbaginifolia (Leadwort-leaved tobacco) (Tex-Mex tobacco).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC   Nicotiana.
OX   NCBI_TaxID=4092;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Leaf;
RX   PubMed=1643285; DOI=10.1007/bf00027080;
RA   Dallmann G., Sticher L., Marshallsay C., Nagy F.;
RT   "Molecular characterization of tobacco cDNAs encoding two small GTP-binding
RT   proteins.";
RL   Plant Mol. Biol. 19:847-857(1992).
CC   -!- FUNCTION: Protein transport. Probably involved in vesicular traffic (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Lipid-anchor
CC       {ECO:0000305}; Cytoplasmic side {ECO:0000305}.
CC   -!- TISSUE SPECIFICITY: Its expression is weak in leaves, higher in stems
CC       and roots, but highest in petals, stigma and stamens.
CC   -!- SIMILARITY: Belongs to the small GTPase superfamily. Rab family.
CC       {ECO:0000305}.
CC   -!- CAUTION: This sequence does not have the CYS-CYS motif at the C-
CC       terminal as do homologous sequences from yeast species. It may be
CC       either geranylgeranylated at an alternative motif or it may be subject
CC       to farnesylation on CYS-215. {ECO:0000305}.
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DR   EMBL; X63874; CAA45351.1; -; mRNA.
DR   PIR; S23523; S23523.
DR   AlphaFoldDB; Q01111; -.
DR   SMR; Q01111; -.
DR   PRIDE; Q01111; -.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003924; F:GTPase activity; IEA:InterPro.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR005225; Small_GTP-bd_dom.
DR   InterPro; IPR001806; Small_GTPase.
DR   Pfam; PF00071; Ras; 1.
DR   SMART; SM00174; RHO; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00231; small_GTP; 1.
DR   PROSITE; PS51419; RAB; 1.
PE   2: Evidence at transcript level;
KW   Cell membrane; GTP-binding; Lipoprotein; Membrane; Nucleotide-binding;
KW   Prenylation; Protein transport; Transport.
FT   CHAIN           1..218
FT                   /note="Ras-related protein YPT3"
FT                   /id="PRO_0000121174"
FT   REGION          186..205
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOTIF           42..50
FT                   /note="Effector region"
FT                   /evidence="ECO:0000255"
FT   BINDING         20..27
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000250"
FT   BINDING         68..72
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000250"
FT   BINDING         126..129
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000250"
FT   LIPID           215
FT                   /note="S-geranylgeranyl cysteine"
FT                   /evidence="ECO:0000250|UniProtKB:P17610"
FT   LIPID           216
FT                   /note="S-geranylgeranyl cysteine"
FT                   /evidence="ECO:0000250|UniProtKB:P17610"
SQ   SEQUENCE   218 AA;  24183 MW;  5A1B5BEAC5BF2443 CRC64;
     MAGYRADDEY DYLFKLVLIG DSGVGKSNLL SRFTKNEFNL ESKSTIGVEF ATKSLNIDNK
     VIKAQIWDTA GQERYRAITS AYYRGAVGAL LVYDVTRHVT YENVTRWLKE LRDHTDPNIV
     VMLIGNKSDL RHLVAVSTDE AKGLAEREGL YFMETSALEA TNVENAFTEA LTQIYRIVSK
     KAVEAGDEGA TSSAPPKGET INIKDEGSSW KKFGCCSS