YPT5_CAEEL
ID YPT5_CAEEL Reviewed; 319 AA.
AC P41883;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1995, sequence version 1.
DT 03-AUG-2022, entry version 125.
DE RecName: Full=Uncharacterized protein F37A4.5;
GN ORFNames=F37A4.5;
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- SIMILARITY: Belongs to the peptidase M67A family. {ECO:0000305}.
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DR EMBL; FO081312; CCD70703.1; -; Genomic_DNA.
DR PIR; S44642; S44642.
DR RefSeq; NP_498470.1; NM_066069.1.
DR AlphaFoldDB; P41883; -.
DR SMR; P41883; -.
DR BioGRID; 50177; 5.
DR IntAct; P41883; 1.
DR STRING; 6239.F37A4.5.1; -.
DR MEROPS; M67.A10; -.
DR EPD; P41883; -.
DR PaxDb; P41883; -.
DR PeptideAtlas; P41883; -.
DR EnsemblMetazoa; F37A4.5.1; F37A4.5.1; WBGene00018135.
DR GeneID; 185404; -.
DR KEGG; cel:CELE_F37A4.5; -.
DR UCSC; F37A4.5; c. elegans.
DR CTD; 185404; -.
DR WormBase; F37A4.5; CE00707; WBGene00018135; -.
DR eggNOG; KOG1555; Eukaryota.
DR HOGENOM; CLU_052991_0_1_1; -.
DR InParanoid; P41883; -.
DR OMA; HAKTNES; -.
DR OrthoDB; 1031881at2759; -.
DR PhylomeDB; P41883; -.
DR PRO; PR:P41883; -.
DR Proteomes; UP000001940; Chromosome III.
DR Bgee; WBGene00018135; Expressed in embryo and 2 other tissues.
DR GO; GO:0008541; C:proteasome regulatory particle, lid subcomplex; IBA:GO_Central.
DR GO; GO:0070122; F:isopeptidase activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0140492; F:metal-dependent deubiquitinase activity; IEA:InterPro.
DR GO; GO:0008237; F:metallopeptidase activity; IBA:GO_Central.
DR GO; GO:0070628; F:proteasome binding; IBA:GO_Central.
DR GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IBA:GO_Central.
DR GO; GO:0016579; P:protein deubiquitination; IBA:GO_Central.
DR InterPro; IPR000555; JAMM/MPN+_dom.
DR InterPro; IPR037518; MPN.
DR Pfam; PF01398; JAB; 1.
DR SMART; SM00232; JAB_MPN; 1.
DR PROSITE; PS50249; MPN; 1.
PE 3: Inferred from homology;
KW Hydrolase; Metal-binding; Metalloprotease; Protease; Reference proteome;
KW Zinc.
FT CHAIN 1..319
FT /note="Uncharacterized protein F37A4.5"
FT /id="PRO_0000213969"
FT DOMAIN 29..164
FT /note="MPN"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01182"
FT MOTIF 111..124
FT /note="JAMM motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01182"
FT BINDING 111
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01182"
FT BINDING 113
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01182"
FT BINDING 124
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01182"
SQ SEQUENCE 319 AA; 35812 MW; 32B9BD1E089C5EA9 CRC64;
MDRLIRSLLM NQNKQATDKL DHPDTSETVN ISSLALLKML RHARSGIPLE VMGLMLGDFV
DDYTINVTDV FAMPQSGTSV TVESVDPVYQ TKHMDLLKLV GRTENVVGWY HSHPGFGCWL
SSVDVNTQQS FEALHPRAVA VVVDPIQSVK GKVMLDAFRS VNPLNLQIRP LAPTAEPRQT
TSNLGHLTKP SLISVVHGLG TKYYSLNVAY RMGSNEQKML MCLNKKSWYD QLNMSTYSEL
EKKQEEKFKS INKLIAVFNK DIDEVKEKPI ADKKGKTQEE VKKFGKINAK QQLQMITSSL
LNDSLCHQLT AMINAKSMT
