YQ7D_SCHPO
ID YQ7D_SCHPO Reviewed; 187 AA.
AC O94585;
DT 20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT 22-SEP-2009, sequence version 3.
DT 25-MAY-2022, entry version 97.
DE RecName: Full=Meiotically up-regulated protein C1442.13c;
DE AltName: Full=Meiotic chromosome segregation protein C1442.13c;
GN ORFNames=SPCC1442.13c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP FUNCTION IN MEIOSIS.
RX PubMed=12161753; DOI=10.1038/ng951;
RA Mata J., Lyne R., Burns G., Baehler J.;
RT "The transcriptional program of meiosis and sporulation in fission yeast.";
RL Nat. Genet. 32:143-147(2002).
RN [3]
RP FUNCTION IN CHROMOSOME SEGREGATION.
RX PubMed=16169489; DOI=10.1016/j.cub.2005.07.059;
RA Gregan J., Rabitsch P.K., Sakem B., Csutak O., Latypov V., Lehmann E.,
RA Kohli J., Nasmyth K.;
RT "Novel genes required for meiotic chromosome segregation are identified by
RT a high-throughput knockout screen in fission yeast.";
RL Curr. Biol. 15:1663-1669(2005).
RN [4]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
CC -!- FUNCTION: Has a role in meiosis and sporulation. Required for meiotic
CC chromosome segregation. {ECO:0000269|PubMed:12161753,
CC ECO:0000269|PubMed:16169489}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:16823372}. Cytoplasm,
CC cytoskeleton, microtubule organizing center, spindle pole body
CC {ECO:0000269|PubMed:16823372}.
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DR EMBL; CU329672; CAA21447.3; -; Genomic_DNA.
DR PIR; T40978; T40978.
DR RefSeq; NP_588327.3; NM_001023318.3.
DR AlphaFoldDB; O94585; -.
DR BioGRID; 275893; 6.
DR STRING; 4896.SPCC1442.13c.1; -.
DR MaxQB; O94585; -.
DR PaxDb; O94585; -.
DR EnsemblFungi; SPCC1442.13c.1; SPCC1442.13c.1:pep; SPCC1442.13c.
DR GeneID; 2539327; -.
DR KEGG; spo:SPCC1442.13c; -.
DR PomBase; SPCC1442.13c; -.
DR VEuPathDB; FungiDB:SPCC1442.13c; -.
DR eggNOG; KOG0154; Eukaryota.
DR HOGENOM; CLU_1448519_0_0_1; -.
DR InParanoid; O94585; -.
DR OMA; ARNDYME; -.
DR PhylomeDB; O94585; -.
DR PRO; PR:O94585; -.
DR Proteomes; UP000002485; Chromosome III.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0072686; C:mitotic spindle; HDA:PomBase.
DR GO; GO:0044732; C:mitotic spindle pole body; HDA:PomBase.
DR GO; GO:0005634; C:nucleus; HDA:PomBase.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0051321; P:meiotic cell cycle; IEP:PomBase.
DR GO; GO:0042254; P:ribosome biogenesis; ISO:PomBase.
DR InterPro; IPR000467; G_patch_dom.
DR Pfam; PF01585; G-patch; 1.
DR SMART; SM00443; G_patch; 1.
DR PROSITE; PS50174; G_PATCH; 1.
PE 1: Evidence at protein level;
KW Cell cycle; Cytoplasm; Cytoskeleton; Meiosis; Nucleus; Reference proteome.
FT CHAIN 1..187
FT /note="Meiotically up-regulated protein C1442.13c"
FT /id="PRO_0000358937"
FT DOMAIN 145..187
FT /note="G-patch"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00092"
FT REGION 15..46
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 119..145
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 187 AA; 21025 MW; 50715F837A916B63 CRC64;
MAIIVEDGSF ITSSQWENVE ASPKPPPRKP KIVQPKKKPS KHLSNEDALE KYEMLFGERR
KEVELDYMSH IAEEETSLSM IEYDRHFALQ TDVKLSKKRK SKLVEMTPKG LKKRKRVQIQ
EGSVSTNTKK RMDGHVVGSS APAINNGKGK QLLEMMGWSR GKGLGSENQG MVDPVVAVVK
NNKQGLH
