YQ9H_SCHPO
ID YQ9H_SCHPO Reviewed; 488 AA.
AC O74867;
DT 11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1998, sequence version 1.
DT 03-AUG-2022, entry version 98.
DE RecName: Full=Uncharacterized protein C18.17c;
GN ORFNames=SPCC18.17c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus
CC {ECO:0000269|PubMed:16823372}.
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DR EMBL; CU329672; CAA21431.1; -; Genomic_DNA.
DR PIR; T41160; T41160.
DR RefSeq; NP_588396.1; NM_001023387.2.
DR AlphaFoldDB; O74867; -.
DR BioGRID; 275732; 74.
DR STRING; 4896.SPCC18.17c.1; -.
DR MaxQB; O74867; -.
DR PaxDb; O74867; -.
DR EnsemblFungi; SPCC18.17c.1; SPCC18.17c.1:pep; SPCC18.17c.
DR GeneID; 2539160; -.
DR KEGG; spo:SPCC18.17c; -.
DR PomBase; SPCC18.17c; -.
DR VEuPathDB; FungiDB:SPCC18.17c; -.
DR eggNOG; KOG4413; Eukaryota.
DR HOGENOM; CLU_559164_0_0_1; -.
DR OMA; CLLHIAQ; -.
DR Reactome; R-SPO-1236978; Cross-presentation of soluble exogenous antigens (endosomes).
DR Reactome; R-SPO-174113; SCF-beta-TrCP mediated degradation of Emi1.
DR Reactome; R-SPO-350562; Regulation of ornithine decarboxylase (ODC).
DR Reactome; R-SPO-382556; ABC-family proteins mediated transport.
DR Reactome; R-SPO-5668541; TNFR2 non-canonical NF-kB pathway.
DR Reactome; R-SPO-5689603; UCH proteinases.
DR Reactome; R-SPO-5689880; Ub-specific processing proteases.
DR Reactome; R-SPO-68949; Orc1 removal from chromatin.
DR Reactome; R-SPO-69017; CDK-mediated phosphorylation and removal of Cdc6.
DR Reactome; R-SPO-69601; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A.
DR Reactome; R-SPO-75815; Ubiquitin-dependent degradation of Cyclin D.
DR Reactome; R-SPO-8854050; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis.
DR Reactome; R-SPO-8948751; Regulation of PTEN stability and activity.
DR Reactome; R-SPO-8951664; Neddylation.
DR Reactome; R-SPO-9755511; KEAP1-NFE2L2 pathway.
DR Reactome; R-SPO-9762114; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2.
DR Reactome; R-SPO-983168; Antigen processing: Ubiquitination & Proteasome degradation.
DR PRO; PR:O74867; -.
DR Proteomes; UP000002485; Chromosome III.
DR GO; GO:0005829; C:cytosol; HDA:PomBase.
DR GO; GO:0005634; C:nucleus; HDA:PomBase.
DR GO; GO:0070682; P:proteasome regulatory particle assembly; ISS:PomBase.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR019538; PSMD5.
DR PANTHER; PTHR13554; PTHR13554; 1.
DR Pfam; PF10508; Proteasom_PSMB; 1.
DR SUPFAM; SSF48371; SSF48371; 1.
PE 4: Predicted;
KW Cytoplasm; Nucleus; Reference proteome.
FT CHAIN 1..488
FT /note="Uncharacterized protein C18.17c"
FT /id="PRO_0000304092"
SQ SEQUENCE 488 AA; 55357 MW; 8AE6039EF95F9C2B CRC64;
MDSIELIPGL PGPGRRLLQL LKDLPSNPSV IVREIPDAID AFRESITPAT RPSCLGLLDT
ILSCFELPIP TEPIMKALGK LLEPMSWADL KKFGIESYLV TGLEHPSTDV EIFCLHLIRR
ANWEKKEIGE PLFEAIMACI NSRSIAVSEE ATVLLFDMAD FPYYFNLIIK RFTFVDYEIM
NSTLRVRWLT LFAKLSTKSP EYLEELIKDD KLVINGDNKD ILLQINFVDV LGIMLEAPFT
YEYISSEKTK YLDTIAQDYK GSADSYTDHI GLKFLPRLCE LHPDAINSLD EKHQLFDAVR
ERMKTNDATS ILLYGVFLSN TVVTQALIKK YGIEDEANRY VPRWLTRRFL MDEPGMSSFA
HALLQPDHNL WMQLWRILPP NTLSTLVNTA SSPIPRSRQL AYQCLLHIAQ NSPIQIASEG
FAIRHLLEAE GDHETCLLRF QVLKTMMESP HGGPKLPFGR YREDILKRLQ QGPIVSGAST
LKVAAETA
