ID   YQC4_SCHPO              Reviewed;         274 AA.
AC   O74466;
DT   19-JUL-2004, integrated into UniProtKB/Swiss-Prot.
DT   11-JUL-2012, sequence version 2.
DT   25-MAY-2022, entry version 92.
DE   RecName: Full=Uncharacterized protein C1739.04c;
GN   ORFNames=SPCC1739.04c;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   REVISION OF GENE MODEL.
RX   PubMed=21511999; DOI=10.1126/science.1203357;
RA   Rhind N., Chen Z., Yassour M., Thompson D.A., Haas B.J., Habib N.,
RA   Wapinski I., Roy S., Lin M.F., Heiman D.I., Young S.K., Furuya K., Guo Y.,
RA   Pidoux A., Chen H.M., Robbertse B., Goldberg J.M., Aoki K., Bayne E.H.,
RA   Berlin A.M., Desjardins C.A., Dobbs E., Dukaj L., Fan L., FitzGerald M.G.,
RA   French C., Gujja S., Hansen K., Keifenheim D., Levin J.Z., Mosher R.A.,
RA   Mueller C.A., Pfiffner J., Priest M., Russ C., Smialowska A., Swoboda P.,
RA   Sykes S.M., Vaughn M., Vengrova S., Yoder R., Zeng Q., Allshire R.,
RA   Baulcombe D., Birren B.W., Brown W., Ekwall K., Kellis M., Leatherwood J.,
RA   Levin H., Margalit H., Martienssen R., Nieduszynski C.A., Spatafora J.W.,
RA   Friedman N., Dalgaard J.Z., Baumann P., Niki H., Regev A., Nusbaum C.;
RT   "Comparative functional genomics of the fission yeasts.";
RL   Science 332:930-936(2011).
RN   [3]
RP   DISRUPTION PHENOTYPE.
RX   PubMed=16169489; DOI=10.1016/j.cub.2005.07.059;
RA   Gregan J., Rabitsch P.K., Sakem B., Csutak O., Latypov V., Lehmann E.,
RA   Kohli J., Nasmyth K.;
RT   "Novel genes required for meiotic chromosome segregation are identified by
RT   a high-throughput knockout screen in fission yeast.";
RL   Curr. Biol. 15:1663-1669(2005).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Single-pass membrane
CC       protein {ECO:0000305}.
CC   -!- DISRUPTION PHENOTYPE: Leads to meiotic defects.
CC       {ECO:0000269|PubMed:16169489}.
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DR   EMBL; CU329672; CAA20778.2; -; Genomic_DNA.
DR   PIR; T41112; T41112.
DR   RefSeq; NP_588412.2; NM_001023403.2.
DR   AlphaFoldDB; O74466; -.
DR   SMR; O74466; -.
DR   BioGRID; 275582; 4.
DR   STRING; 4896.SPCC1739.04c.1; -.
DR   MaxQB; O74466; -.
DR   PaxDb; O74466; -.
DR   EnsemblFungi; SPCC1739.04c.1; SPCC1739.04c.1:pep; SPCC1739.04c.
DR   GeneID; 2539009; -.
DR   KEGG; spo:SPCC1739.04c; -.
DR   PomBase; SPCC1739.04c; -.
DR   VEuPathDB; FungiDB:SPCC1739.04c; -.
DR   HOGENOM; CLU_1031170_0_0_1; -.
DR   OMA; NPWMKKE; -.
DR   PRO; PR:O74466; -.
DR   Proteomes; UP000002485; Chromosome III.
DR   GO; GO:0005737; C:cytoplasm; HDA:PomBase.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0035974; C:meiotic spindle pole body; IDA:PomBase.
DR   GO; GO:0000212; P:meiotic spindle organization; IMP:PomBase.
PE   4: Predicted;
KW   Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT   CHAIN           1..274
FT                   /note="Uncharacterized protein C1739.04c"
FT                   /id="PRO_0000116889"
FT   TRANSMEM        238..258
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   274 AA;  30654 MW;  E2835FE2EC91B312 CRC64;
     MNSVPNELTK SQELFGQISK ISHSKISISE LITLLDIHYS ELFTKNPWMK KEVRKLASEF
     VENDPNHLLS KQDACHLIEA FVNVSITSPT LLTSVDPVLY QQLEASSTND ISTVFEDESS
     SLPIILHPKF SSMQVRTVTS PKDAFVSAFE ENKFHFAATE SFFEMAFSKI DSCLTSVQST
     KKDSIKSRLV ERYIQNEESV KRPDKSPFDT MTEATLQSSS DKSENFTKTL LSNVLSTILS
     VQVIFATVIA LIAISVFCFL HTSSKTTSSK TRPS