YQEH_SCHPO
ID YQEH_SCHPO Reviewed; 525 AA.
AC O74899;
DT 05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1998, sequence version 1.
DT 25-MAY-2022, entry version 116.
DE RecName: Full=Uncharacterized transporter C576.17c;
GN ORFNames=SPCC576.17c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1] {ECO:0000312|EMBL:CAA21196.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2] {ECO:0000305}
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-55, AND IDENTIFICATION BY
RP MASS SPECTROMETRY.
RX PubMed=18257517; DOI=10.1021/pr7006335;
RA Wilson-Grady J.T., Villen J., Gygi S.P.;
RT "Phosphoproteome analysis of fission yeast.";
RL J. Proteome Res. 7:1088-1097(2008).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000255}; Multi-pass membrane
CC protein {ECO:0000255}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. CAR1 family.
CC {ECO:0000255}.
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DR EMBL; CU329672; CAA21196.1; -; Genomic_DNA.
DR PIR; T41427; T41427.
DR RefSeq; NP_588443.1; NM_001023434.2.
DR AlphaFoldDB; O74899; -.
DR SMR; O74899; -.
DR iPTMnet; O74899; -.
DR MaxQB; O74899; -.
DR PaxDb; O74899; -.
DR EnsemblFungi; SPCC576.17c.1; SPCC576.17c.1:pep; SPCC576.17c.
DR GeneID; 2539554; -.
DR KEGG; spo:SPCC576.17c; -.
DR PomBase; SPCC576.17c; -.
DR VEuPathDB; FungiDB:SPCC576.17c; -.
DR eggNOG; KOG0255; Eukaryota.
DR HOGENOM; CLU_008455_11_5_1; -.
DR InParanoid; O74899; -.
DR OMA; NIADYHI; -.
DR PhylomeDB; O74899; -.
DR PRO; PR:O74899; -.
DR Proteomes; UP000002485; Chromosome III.
DR GO; GO:0005737; C:cytoplasm; HDA:PomBase.
DR GO; GO:0005887; C:integral component of plasma membrane; ISS:PomBase.
DR GO; GO:0031925; F:pyridoxal transmembrane transporter activity; ISS:PomBase.
DR GO; GO:0031927; F:pyridoxamine transmembrane transporter activity; ISS:PomBase.
DR GO; GO:0031928; F:pyridoxine transmembrane transporter activity; ISS:PomBase.
DR GO; GO:0022857; F:transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:1903090; P:pyridoxal transmembrane transport; ISS:PomBase.
DR GO; GO:1903091; P:pyridoxamine transmembrane transport; ISS:PomBase.
DR GO; GO:1903092; P:pyridoxine transmembrane transport; ISS:PomBase.
DR GO; GO:0055085; P:transmembrane transport; IBA:GO_Central.
DR Gene3D; 1.20.1250.20; -; 1.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR005829; Sugar_transporter_CS.
DR Pfam; PF07690; MFS_1; 1.
DR SUPFAM; SSF103473; SSF103473; 1.
DR PROSITE; PS50850; MFS; 1.
DR PROSITE; PS00216; SUGAR_TRANSPORT_1; 1.
PE 1: Evidence at protein level;
KW Membrane; Phosphoprotein; Reference proteome; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..525
FT /note="Uncharacterized transporter C576.17c"
FT /id="PRO_0000372795"
FT TRANSMEM 81..101
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 120..140
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 147..167
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 173..193
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 208..228
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 238..258
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 295..315
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 318..338
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 350..370
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 388..408
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 413..433
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 454..474
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 484..504
FT /note="Helical"
FT /evidence="ECO:0000255"
FT MOD_RES 55
FT /note="Phosphoserine"
FT /evidence="ECO:0000269|PubMed:18257517"
SQ SEQUENCE 525 AA; 59322 MW; 2300BF92E0B48993 CRC64;
MNDTNDVMHV HSESISPKKN DLDIELGESV VEPHLSNNSI AKLDTYELEE NEDISDYAYK
LAGISNEHPA HPQNWGWWKK AYIVLLSTSL QMYVFWTPNF YPGVQDSVME LWHLSSQVSL
LGQSMFVLGV ALGPLFLGPL SDLLGRKLVY IGSLIIYVCF CISCALARNY AQLVISMLIM
GVVGSTALGN VAGAVADVLG DEDSNWGMYM FIFMCSVASV GSPMGTGVAE NPKLTWRWLY
WIDVIVGGFF IILFVFTPET LPAIVIQRYE QKRQGLPVSW FPQFSLKKLA KDTYFVFFMA
IKIFFSEPIV SSLGIYNGFV NGLLYFFLQA IWPVYFSIYK MSDMAASCTY MAAMPACVIL
LWFEPLQCWL YKRDKRKHQN RLRPEARFIM TLFYVWGFPI GIFMFAFCSK VHIHYIVSLI
GLTIFNIADY HIWQAMLLYV TDAYPNVSAS AVAAFELPSN LGAVGFIHLS ALMFSRMNVH
WATAVVGFAS LPLIALIYAL YFYGDRIRAR SKLASQRVPI NTAAH
