YQF7_SCHPO
ID YQF7_SCHPO Reviewed; 571 AA.
AC O94400;
DT 11-SEP-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1999, sequence version 1.
DT 25-MAY-2022, entry version 131.
DE RecName: Full=PHD and RING finger domain-containing protein C126.07c;
GN ORFNames=SPCC126.07c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus
CC {ECO:0000269|PubMed:16823372}.
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DR EMBL; CU329672; CAA22476.1; -; Genomic_DNA.
DR PIR; T40911; T40911.
DR RefSeq; NP_588450.1; NM_001023441.2.
DR AlphaFoldDB; O94400; -.
DR SMR; O94400; -.
DR BioGRID; 275631; 7.
DR STRING; 4896.SPCC126.07c.1; -.
DR PaxDb; O94400; -.
DR PRIDE; O94400; -.
DR EnsemblFungi; SPCC126.07c.1; SPCC126.07c.1:pep; SPCC126.07c.
DR GeneID; 2539058; -.
DR KEGG; spo:SPCC126.07c; -.
DR PomBase; SPCC126.07c; -.
DR VEuPathDB; FungiDB:SPCC126.07c; -.
DR eggNOG; KOG0825; Eukaryota.
DR HOGENOM; CLU_026721_0_0_1; -.
DR InParanoid; O94400; -.
DR OMA; AWQRRFE; -.
DR PhylomeDB; O94400; -.
DR PRO; PR:O94400; -.
DR Proteomes; UP000002485; Chromosome III.
DR GO; GO:0005829; C:cytosol; HDA:PomBase.
DR GO; GO:0005634; C:nucleus; HDA:PomBase.
DR GO; GO:0061630; F:ubiquitin protein ligase activity; ISO:PomBase.
DR GO; GO:0008270; F:zinc ion binding; ISM:PomBase.
DR GO; GO:0000122; P:negative regulation of transcription by RNA polymerase II; ISO:PomBase.
DR GO; GO:0070647; P:protein modification by small protein conjugation or removal; IC:PomBase.
DR Gene3D; 3.30.40.10; -; 2.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR Pfam; PF00628; PHD; 1.
DR SMART; SM00249; PHD; 1.
DR SMART; SM00184; RING; 2.
DR SUPFAM; SSF57903; SSF57903; 1.
DR PROSITE; PS01359; ZF_PHD_1; 1.
DR PROSITE; PS50016; ZF_PHD_2; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Cytoplasm; Metal-binding; Nucleus; Reference proteome; Repeat; Zinc;
KW Zinc-finger.
FT CHAIN 1..571
FT /note="PHD and RING finger domain-containing protein
FT C126.07c"
FT /id="PRO_0000303919"
FT ZN_FING 18..79
FT /note="RING-type 1; atypical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00175"
FT ZN_FING 122..170
FT /note="PHD-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00146"
FT ZN_FING 125..168
FT /note="RING-type 2; degenerate"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00175"
FT REGION 305..377
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 305..324
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 325..346
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 357..377
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 571 AA; 64468 MW; 34C23259CA54E6CB CRC64;
MNAEEDPKPA DSDSSEECII CLSNLPNCPL DQWDSSSVPA SISSTLDGLR IAKIPCGHYF
HNHCLESWCR VANTCPLCRT EFLKVDVLEF VKGPWYRAYP VEEKTQSVAN AGEPFEDEGS
ETCRCVICGR SDHAEVLLLC DGCDDAYHTY CLNMDAVPIE EFYCPNCVLL NYQENETLSS
RISLSRRGQT RRRRVGAAAR ASRVSQQQQR AWTRAWNAIR NRAWDALNSD LSYYGMQQER
LPARDVSSEL LRRRIESARL RSNQLNEPVE QPRVVQTPVT NASEQQAWND FDEILHANSS
VHSVATEATI SNPRPSSGRF QQTPIEEHHQ QDTRFVNDPN STSHDRRQKR PTRRHIPCSN
KSSGSSTVLG NNSSSKSENS FLASLISNIN QPSTSRIDTS FMLSLQHEIK NSHSEASDGT
SDVHLTPLFS NLSPRPSHVP LSPREISNDN LDDHLIELSE PGEIVDNHLV NDTSMHQRRT
SGRHDLVHSS KKVSYETKYR IERLVNAALK PYYREAKISK DQFALFNKNI CRSVYTALSD
GTLSLEGPQQ HKISKTIREK VVNCIQSLSN D
