ID   YQFA_ECOL6              Reviewed;         219 AA.
AC   P67154; Q46827;
DT   11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   03-AUG-2022, entry version 83.
DE   RecName: Full=UPF0073 inner membrane protein YqfA;
GN   Name=yqfA; OrderedLocusNames=c3480;
OS   Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=199310;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CFT073 / ATCC 700928 / UPEC;
RX   PubMed=12471157; DOI=10.1073/pnas.252529799;
RA   Welch R.A., Burland V., Plunkett G. III, Redford P., Roesch P., Rasko D.,
RA   Buckles E.L., Liou S.-R., Boutin A., Hackett J., Stroud D., Mayhew G.F.,
RA   Rose D.J., Zhou S., Schwartz D.C., Perna N.T., Mobley H.L.T.,
RA   Donnenberg M.S., Blattner F.R.;
RT   "Extensive mosaic structure revealed by the complete genome sequence of
RT   uropathogenic Escherichia coli.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:17020-17024(2002).
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC       membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UPF0073 (Hly-III) family. {ECO:0000305}.
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DR   EMBL; AE014075; AAN81928.1; -; Genomic_DNA.
DR   RefSeq; WP_000250274.1; NC_004431.1.
DR   AlphaFoldDB; P67154; -.
DR   SMR; P67154; -.
DR   STRING; 199310.c3480; -.
DR   EnsemblBacteria; AAN81928; AAN81928; c3480.
DR   GeneID; 66673227; -.
DR   KEGG; ecc:c3480; -.
DR   eggNOG; COG1272; Bacteria.
DR   HOGENOM; CLU_051078_1_0_6; -.
DR   OMA; HEVFHSL; -.
DR   BioCyc; ECOL199310:C3480-MON; -.
DR   Proteomes; UP000001410; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0019835; P:cytolysis; IEA:InterPro.
DR   InterPro; IPR004254; AdipoR/HlyIII-related.
DR   InterPro; IPR005744; Hy-lIII.
DR   PANTHER; PTHR20855; PTHR20855; 1.
DR   Pfam; PF03006; HlyIII; 1.
DR   TIGRFAMs; TIGR01065; hlyIII; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..219
FT                   /note="UPF0073 inner membrane protein YqfA"
FT                   /id="PRO_0000176899"
FT   TOPO_DOM        1..23
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        24..44
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        45..53
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        54..74
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        75..90
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        91..111
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        112..113
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        114..134
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        135..138
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        139..159
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        160..165
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        166..186
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        187..195
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        196..216
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        217..219
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   219 AA;  23847 MW;  F1D863D2D1A30DA0 CRC64;
     MVQKPLIKQG YSLAEEIANS VSHGIGLVFG IVGLVLLLVQ AVDLNASATA ITSYSLYGGS
     MILLFLASTL YHAIPHQRAK MWLKKFDHCA IYLLIAGTYT PFLLVGLDSP LARGLMIVIW
     SLALLGILFK LTIAHRFKIL SLVTYLAMGW LSLVVIYEMA VKLAAGSVTL LAVGGVVYSL
     GVIFYVCKRI PYNHAIWHGF VLGGSVCHFL AIYLYIGQA