ID   YQGF_HELPJ              Reviewed;         134 AA.
AC   Q9ZMA5;
DT   16-JUN-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1999, sequence version 1.
DT   25-MAY-2022, entry version 103.
DE   RecName: Full=Putative pre-16S rRNA nuclease {ECO:0000255|HAMAP-Rule:MF_00651};
DE            EC=3.1.-.- {ECO:0000255|HAMAP-Rule:MF_00651};
GN   OrderedLocusNames=jhp_0317;
OS   Helicobacter pylori (strain J99 / ATCC 700824) (Campylobacter pylori J99).
OC   Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales;
OC   Helicobacteraceae; Helicobacter.
OX   NCBI_TaxID=85963;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=J99 / ATCC 700824;
RX   PubMed=9923682; DOI=10.1038/16495;
RA   Alm R.A., Ling L.-S.L., Moir D.T., King B.L., Brown E.D., Doig P.C.,
RA   Smith D.R., Noonan B., Guild B.C., deJonge B.L., Carmel G., Tummino P.J.,
RA   Caruso A., Uria-Nickelsen M., Mills D.M., Ives C., Gibson R., Merberg D.,
RA   Mills S.D., Jiang Q., Taylor D.E., Vovis G.F., Trust T.J.;
RT   "Genomic sequence comparison of two unrelated isolates of the human gastric
RT   pathogen Helicobacter pylori.";
RL   Nature 397:176-180(1999).
CC   -!- FUNCTION: Could be a nuclease involved in processing of the 5'-end of
CC       pre-16S rRNA. {ECO:0000255|HAMAP-Rule:MF_00651}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00651}.
CC   -!- SIMILARITY: Belongs to the YqgF nuclease family. {ECO:0000255|HAMAP-
CC       Rule:MF_00651}.
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DR   EMBL; AE001439; AAD05908.1; -; Genomic_DNA.
DR   PIR; E71945; E71945.
DR   RefSeq; WP_000599187.1; NZ_CP011330.1.
DR   AlphaFoldDB; Q9ZMA5; -.
DR   SMR; Q9ZMA5; -.
DR   STRING; 85963.jhp_0317; -.
DR   EnsemblBacteria; AAD05908; AAD05908; jhp_0317.
DR   KEGG; hpj:jhp_0317; -.
DR   PATRIC; fig|85963.30.peg.696; -.
DR   eggNOG; COG0816; Bacteria.
DR   OMA; CDVGLKR; -.
DR   Proteomes; UP000000804; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0000967; P:rRNA 5'-end processing; IEA:UniProtKB-UniRule.
DR   CDD; cd16964; YqgF; 1.
DR   Gene3D; 3.30.420.140; -; 1.
DR   HAMAP; MF_00651; Nuclease_YqgF; 1.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR005227; YqgF.
DR   InterPro; IPR006641; YqgF/RNaseH-like_dom.
DR   InterPro; IPR037027; YqgF/RNaseH-like_dom_sf.
DR   PANTHER; PTHR33317; PTHR33317; 1.
DR   Pfam; PF03652; RuvX; 1.
DR   SMART; SM00732; YqgFc; 1.
DR   SUPFAM; SSF53098; SSF53098; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Hydrolase; Nuclease; Ribosome biogenesis.
FT   CHAIN           1..134
FT                   /note="Putative pre-16S rRNA nuclease"
FT                   /id="PRO_0000172074"
SQ   SEQUENCE   134 AA;  15122 MW;  C4DF777908C983D2 CRC64;
     MILACDVGLK RIGIAALLNG VILPLEAILR HNRNQASRDL SDLLRKKDIQ VLVVGKPNES
     YADTHARIEH FIKLVDFKGE IVFINEDNSS VEAYENLEHL GKKNKRIATK DGRLDSLSAC
     RILERYCQQV LKKG