YQGF_LACAC
ID YQGF_LACAC Reviewed; 142 AA.
AC Q5FLW4;
DT 26-APR-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2005, sequence version 1.
DT 03-AUG-2022, entry version 87.
DE RecName: Full=Putative pre-16S rRNA nuclease {ECO:0000255|HAMAP-Rule:MF_00651};
DE EC=3.1.-.- {ECO:0000255|HAMAP-Rule:MF_00651};
GN OrderedLocusNames=LBA0419;
OS Lactobacillus acidophilus (strain ATCC 700396 / NCK56 / N2 / NCFM).
OC Bacteria; Firmicutes; Bacilli; Lactobacillales; Lactobacillaceae;
OC Lactobacillus.
OX NCBI_TaxID=272621;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700396 / NCK56 / N2 / NCFM;
RX PubMed=15671160; DOI=10.1073/pnas.0409188102;
RA Altermann E., Russell W.M., Azcarate-Peril M.A., Barrangou R., Buck B.L.,
RA McAuliffe O., Souther N., Dobson A., Duong T., Callanan M., Lick S.,
RA Hamrick A., Cano R., Klaenhammer T.R.;
RT "Complete genome sequence of the probiotic lactic acid bacterium
RT Lactobacillus acidophilus NCFM.";
RL Proc. Natl. Acad. Sci. U.S.A. 102:3906-3912(2005).
CC -!- FUNCTION: Could be a nuclease involved in processing of the 5'-end of
CC pre-16S rRNA. {ECO:0000255|HAMAP-Rule:MF_00651}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00651}.
CC -!- SIMILARITY: Belongs to the YqgF nuclease family. {ECO:0000255|HAMAP-
CC Rule:MF_00651}.
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DR EMBL; CP000033; AAV42310.1; -; Genomic_DNA.
DR RefSeq; WP_003549192.1; NC_006814.3.
DR RefSeq; YP_193341.1; NC_006814.3.
DR AlphaFoldDB; Q5FLW4; -.
DR SMR; Q5FLW4; -.
DR STRING; 272621.LBA0419; -.
DR EnsemblBacteria; AAV42310; AAV42310; LBA0419.
DR GeneID; 56942024; -.
DR KEGG; lac:LBA0419; -.
DR PATRIC; fig|272621.13.peg.404; -.
DR eggNOG; COG0816; Bacteria.
DR HOGENOM; CLU_098240_2_0_9; -.
DR OMA; PMGWTAQ; -.
DR BioCyc; LACI272621:G1G49-413-MON; -.
DR Proteomes; UP000006381; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0000967; P:rRNA 5'-end processing; IEA:UniProtKB-UniRule.
DR CDD; cd16964; YqgF; 1.
DR Gene3D; 3.30.420.140; -; 1.
DR HAMAP; MF_00651; Nuclease_YqgF; 1.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR005227; YqgF.
DR InterPro; IPR006641; YqgF/RNaseH-like_dom.
DR InterPro; IPR037027; YqgF/RNaseH-like_dom_sf.
DR PANTHER; PTHR33317; PTHR33317; 1.
DR Pfam; PF03652; RuvX; 1.
DR SMART; SM00732; YqgFc; 1.
DR SUPFAM; SSF53098; SSF53098; 1.
DR TIGRFAMs; TIGR00250; RNAse_H_YqgF; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Hydrolase; Nuclease; Reference proteome; Ribosome biogenesis.
FT CHAIN 1..142
FT /note="Putative pre-16S rRNA nuclease"
FT /id="PRO_0000172076"
SQ SEQUENCE 142 AA; 16160 MW; 017094297B7F3C20 CRC64;
MRLLGLDVGS KTVGVAISDE LGITAQKLET IQIDETKYNF GMRPLKKLVR QYDVDGFVLG
LPKNMDGTSG NSVARSKAYG KRLEEKFNLP VYYSDERLTT IESRRVLIED AGMHDRKKRK
QVIDQMAAVL ILQNYLDLHR KD