ID   YQGF_MYCS2              Reviewed;         170 AA.
AC   A0QWQ5; I7FD52;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   09-JAN-2007, sequence version 1.
DT   25-MAY-2022, entry version 96.
DE   RecName: Full=Putative pre-16S rRNA nuclease {ECO:0000255|HAMAP-Rule:MF_00651};
DE            EC=3.1.-.- {ECO:0000255|HAMAP-Rule:MF_00651};
GN   OrderedLocusNames=MSMEG_3026, MSMEI_2951;
OS   Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium
OS   smegmatis).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycolicibacterium.
OX   NCBI_TaxID=246196;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700084 / mc(2)155;
RA   Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C.,
RA   Fraser C.M.;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700084 / mc(2)155;
RX   PubMed=17295914; DOI=10.1186/gb-2007-8-2-r20;
RA   Deshayes C., Perrodou E., Gallien S., Euphrasie D., Schaeffer C.,
RA   Van-Dorsselaer A., Poch O., Lecompte O., Reyrat J.-M.;
RT   "Interrupted coding sequences in Mycobacterium smegmatis: authentic
RT   mutations or sequencing errors?";
RL   Genome Biol. 8:R20.1-R20.9(2007).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700084 / mc(2)155;
RX   PubMed=18955433; DOI=10.1101/gr.081901.108;
RA   Gallien S., Perrodou E., Carapito C., Deshayes C., Reyrat J.-M.,
RA   Van Dorsselaer A., Poch O., Schaeffer C., Lecompte O.;
RT   "Ortho-proteogenomics: multiple proteomes investigation through orthology
RT   and a new MS-based protocol.";
RL   Genome Res. 19:128-135(2009).
CC   -!- FUNCTION: Could be a nuclease involved in processing of the 5'-end of
CC       pre-16S rRNA. {ECO:0000255|HAMAP-Rule:MF_00651}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00651}.
CC   -!- SIMILARITY: Belongs to the YqgF nuclease family. {ECO:0000255|HAMAP-
CC       Rule:MF_00651}.
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DR   EMBL; CP000480; ABK73002.1; -; Genomic_DNA.
DR   EMBL; CP001663; AFP39415.1; -; Genomic_DNA.
DR   RefSeq; WP_003894407.1; NZ_SIJM01000002.1.
DR   RefSeq; YP_887343.1; NC_008596.1.
DR   AlphaFoldDB; A0QWQ5; -.
DR   SMR; A0QWQ5; -.
DR   STRING; 246196.MSMEI_2951; -.
DR   EnsemblBacteria; ABK73002; ABK73002; MSMEG_3026.
DR   EnsemblBacteria; AFP39415; AFP39415; MSMEI_2951.
DR   GeneID; 66734433; -.
DR   KEGG; msg:MSMEI_2951; -.
DR   KEGG; msm:MSMEG_3026; -.
DR   PATRIC; fig|246196.19.peg.2988; -.
DR   eggNOG; COG0816; Bacteria.
DR   OMA; PMGWTAQ; -.
DR   OrthoDB; 2075502at2; -.
DR   Proteomes; UP000000757; Chromosome.
DR   Proteomes; UP000006158; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0000967; P:rRNA 5'-end processing; IEA:UniProtKB-UniRule.
DR   CDD; cd16964; YqgF; 1.
DR   Gene3D; 3.30.420.140; -; 1.
DR   HAMAP; MF_00651; Nuclease_YqgF; 1.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR005227; YqgF.
DR   InterPro; IPR006641; YqgF/RNaseH-like_dom.
DR   InterPro; IPR037027; YqgF/RNaseH-like_dom_sf.
DR   PANTHER; PTHR33317; PTHR33317; 1.
DR   Pfam; PF03652; RuvX; 1.
DR   SMART; SM00732; YqgFc; 1.
DR   SUPFAM; SSF53098; SSF53098; 1.
DR   TIGRFAMs; TIGR00250; RNAse_H_YqgF; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Hydrolase; Nuclease; Reference proteome; Ribosome biogenesis.
FT   CHAIN           1..170
FT                   /note="Putative pre-16S rRNA nuclease"
FT                   /id="PRO_1000131050"
FT   REGION          1..22
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..21
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   170 AA;  18139 MW;  4B7ED27F92D6BE71 CRC64;
     MGTDDRLPDR PGADDPGRGR RIGIDVGTVR IGVASSDPDG ILATPVETVA RDKRDKTGKH
     VRRLAALVKE YEAVEVIVGL PRTLGDRASA SAHDAVDVAE QLARRIAPTP VRLADERLTT
     VSAQRSLREA GVRARGQKAV IDQVAAVGIL QGWLDQRRAA LAARREGTDG