ID   YQGF_SALTI              Reviewed;         138 AA.
AC   Q8Z3V1;
DT   16-JUN-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   25-MAY-2022, entry version 110.
DE   RecName: Full=Putative pre-16S rRNA nuclease {ECO:0000255|HAMAP-Rule:MF_00651};
DE            EC=3.1.-.- {ECO:0000255|HAMAP-Rule:MF_00651};
GN   Name=yqgF {ECO:0000255|HAMAP-Rule:MF_00651};
GN   OrderedLocusNames=STY3250, t3009;
OS   Salmonella typhi.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=90370;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CT18;
RX   PubMed=11677608; DOI=10.1038/35101607;
RA   Parkhill J., Dougan G., James K.D., Thomson N.R., Pickard D., Wain J.,
RA   Churcher C.M., Mungall K.L., Bentley S.D., Holden M.T.G., Sebaihia M.,
RA   Baker S., Basham D., Brooks K., Chillingworth T., Connerton P., Cronin A.,
RA   Davis P., Davies R.M., Dowd L., White N., Farrar J., Feltwell T.,
RA   Hamlin N., Haque A., Hien T.T., Holroyd S., Jagels K., Krogh A.,
RA   Larsen T.S., Leather S., Moule S., O'Gaora P., Parry C., Quail M.A.,
RA   Rutherford K.M., Simmonds M., Skelton J., Stevens K., Whitehead S.,
RA   Barrell B.G.;
RT   "Complete genome sequence of a multiple drug resistant Salmonella enterica
RT   serovar Typhi CT18.";
RL   Nature 413:848-852(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700931 / Ty2;
RX   PubMed=12644504; DOI=10.1128/jb.185.7.2330-2337.2003;
RA   Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J., Burland V.,
RA   Kodoyianni V., Schwartz D.C., Blattner F.R.;
RT   "Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and
RT   CT18.";
RL   J. Bacteriol. 185:2330-2337(2003).
RN   [3]
RP   DISRUPTION PHENOTYPE.
RC   STRAIN=STH2370;
RX   PubMed=15280224; DOI=10.1534/genetics.104.026682;
RA   Hidalgo A.A., Trombert A.N., Castro-Alonso J.C., Santiviago C.A.,
RA   Tesser B.R., Youderian P., Mora G.C.;
RT   "Insertions of mini-Tn10 transposon T-POP in Salmonella enterica sv.
RT   typhi.";
RL   Genetics 167:1069-1077(2004).
CC   -!- FUNCTION: Could be a nuclease involved in processing of the 5'-end of
CC       pre-16S rRNA. {ECO:0000255|HAMAP-Rule:MF_00651}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00651}.
CC   -!- DISRUPTION PHENOTYPE: Essential, it cannot be disrupted; cell division
CC       is arrested and cells form unseparated doublets with well-defined
CC       septa. {ECO:0000269|PubMed:15280224}.
CC   -!- SIMILARITY: Belongs to the YqgF nuclease family. {ECO:0000255|HAMAP-
CC       Rule:MF_00651}.
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DR   EMBL; AL513382; CAD02921.1; -; Genomic_DNA.
DR   EMBL; AE014613; AAO70561.1; -; Genomic_DNA.
DR   RefSeq; NP_457489.1; NC_003198.1.
DR   RefSeq; WP_001285491.1; NZ_WSUR01000049.1.
DR   AlphaFoldDB; Q8Z3V1; -.
DR   SMR; Q8Z3V1; -.
DR   STRING; 220341.16504174; -.
DR   EnsemblBacteria; AAO70561; AAO70561; t3009.
DR   KEGG; stt:t3009; -.
DR   KEGG; sty:STY3250; -.
DR   PATRIC; fig|220341.7.peg.3314; -.
DR   eggNOG; COG0816; Bacteria.
DR   HOGENOM; CLU_098240_3_0_6; -.
DR   OMA; PMGWTAQ; -.
DR   Proteomes; UP000000541; Chromosome.
DR   Proteomes; UP000002670; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0000967; P:rRNA 5'-end processing; IEA:UniProtKB-UniRule.
DR   CDD; cd16964; YqgF; 1.
DR   Gene3D; 3.30.420.140; -; 1.
DR   HAMAP; MF_00651; Nuclease_YqgF; 1.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR005227; YqgF.
DR   InterPro; IPR006641; YqgF/RNaseH-like_dom.
DR   InterPro; IPR037027; YqgF/RNaseH-like_dom_sf.
DR   PANTHER; PTHR33317; PTHR33317; 1.
DR   Pfam; PF03652; RuvX; 1.
DR   SMART; SM00732; YqgFc; 1.
DR   SUPFAM; SSF53098; SSF53098; 1.
DR   TIGRFAMs; TIGR00250; RNAse_H_YqgF; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Hydrolase; Nuclease; Ribosome biogenesis.
FT   CHAIN           1..138
FT                   /note="Putative pre-16S rRNA nuclease"
FT                   /id="PRO_0000172132"
SQ   SEQUENCE   138 AA;  15218 MW;  8710BBF22DAB1E3F CRC64;
     MSDTLLAFDF GTKSIGVAIG QRITGTARPL PAIKAQDGTP DWTLIERLLK EWQPDEIIVG
     LPLNMDGTEQ PLTARARKFA NRIHGRFGVT VTLHDERLST VEARSGLFER GGYRALNKGK
     VDSASAVIIL ESYFEQGY