ID   YQGF_THET8              Reviewed;         135 AA.
AC   Q5SHA1; P83694;
DT   26-APR-2005, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   25-MAY-2022, entry version 96.
DE   RecName: Full=Putative pre-16S rRNA nuclease {ECO:0000255|HAMAP-Rule:MF_00651};
DE            EC=3.1.-.- {ECO:0000255|HAMAP-Rule:MF_00651};
GN   OrderedLocusNames=TTHA1829;
OS   Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8).
OC   Bacteria; Deinococcus-Thermus; Deinococci; Thermales; Thermaceae; Thermus.
OX   NCBI_TaxID=300852;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 27634 / DSM 579 / HB8;
RA   Masui R., Kurokawa K., Nakagawa N., Tokunaga F., Koyama Y., Shibata T.,
RA   Oshima T., Yokoyama S., Yasunaga T., Kuramitsu S.;
RT   "Complete genome sequence of Thermus thermophilus HB8.";
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   STRUCTURE BY NMR OF 1-98.
RG   RIKEN structural genomics initiative (RSGI);
RT   "Solution structure of the YqgF-family protein (N-terminal fragment).";
RL   Submitted (OCT-2003) to the PDB data bank.
CC   -!- FUNCTION: Could be a nuclease involved in processing of the 5'-end of
CC       pre-16S rRNA. {ECO:0000255|HAMAP-Rule:MF_00651}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00651}.
CC   -!- SIMILARITY: Belongs to the YqgF nuclease family. {ECO:0000255|HAMAP-
CC       Rule:MF_00651}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AP008226; BAD71652.1; -; Genomic_DNA.
DR   RefSeq; WP_011173853.1; NC_006461.1.
DR   RefSeq; YP_145095.1; NC_006461.1.
DR   PDB; 1IV0; NMR; -; A=1-98.
DR   PDBsum; 1IV0; -.
DR   AlphaFoldDB; Q5SHA1; -.
DR   SMR; Q5SHA1; -.
DR   STRING; 300852.55773211; -.
DR   EnsemblBacteria; BAD71652; BAD71652; BAD71652.
DR   GeneID; 3168171; -.
DR   KEGG; ttj:TTHA1829; -.
DR   PATRIC; fig|300852.9.peg.1800; -.
DR   eggNOG; COG0816; Bacteria.
DR   HOGENOM; CLU_098240_2_2_0; -.
DR   OMA; VQILELW; -.
DR   PhylomeDB; Q5SHA1; -.
DR   EvolutionaryTrace; Q5SHA1; -.
DR   Proteomes; UP000000532; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0000967; P:rRNA 5'-end processing; IEA:UniProtKB-UniRule.
DR   CDD; cd16964; YqgF; 1.
DR   Gene3D; 3.30.420.140; -; 1.
DR   HAMAP; MF_00651; Nuclease_YqgF; 1.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR005227; YqgF.
DR   InterPro; IPR006641; YqgF/RNaseH-like_dom.
DR   InterPro; IPR037027; YqgF/RNaseH-like_dom_sf.
DR   PANTHER; PTHR33317; PTHR33317; 1.
DR   Pfam; PF03652; RuvX; 1.
DR   SMART; SM00732; YqgFc; 1.
DR   SUPFAM; SSF53098; SSF53098; 1.
DR   TIGRFAMs; TIGR00250; RNAse_H_YqgF; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Cytoplasm; Hydrolase; Nuclease; Reference proteome;
KW   Ribosome biogenesis.
FT   CHAIN           1..135
FT                   /note="Putative pre-16S rRNA nuclease"
FT                   /id="PRO_0000172164"
FT   STRAND          3..18
FT                   /evidence="ECO:0007829|PDB:1IV0"
FT   STRAND          28..32
FT                   /evidence="ECO:0007829|PDB:1IV0"
FT   HELIX           36..49
FT                   /evidence="ECO:0007829|PDB:1IV0"
FT   STRAND          54..58
FT                   /evidence="ECO:0007829|PDB:1IV0"
FT   STRAND          65..67
FT                   /evidence="ECO:0007829|PDB:1IV0"
FT   HELIX           75..83
FT                   /evidence="ECO:0007829|PDB:1IV0"
FT   STRAND          87..91
FT                   /evidence="ECO:0007829|PDB:1IV0"
SQ   SEQUENCE   135 AA;  14893 MW;  76828FC87C617C08 CRC64;
     MRVGALDVGE ARIGLAVGEE GVPLASGRGY LVRKTLEEDV EALLDFVRRE GLGKLVVGLP
     LRTDLKESAQ AGKVLPLVEA LRARGVEVEL WDERFTTKLA QERLKHAPKR LRRDKGKLDE
     LAAVVLLEDY LARGI