ID   YQGF_TROWT              Reviewed;         145 AA.
AC   Q83GD2;
DT   26-APR-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   25-MAY-2022, entry version 105.
DE   RecName: Full=Putative pre-16S rRNA nuclease {ECO:0000255|HAMAP-Rule:MF_00651};
DE            EC=3.1.-.- {ECO:0000255|HAMAP-Rule:MF_00651};
GN   OrderedLocusNames=TWT_375;
OS   Tropheryma whipplei (strain Twist) (Whipple's bacillus).
OC   Bacteria; Actinobacteria; Micrococcales; Tropherymataceae; Tropheryma.
OX   NCBI_TaxID=203267;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Twist;
RX   PubMed=12902375; DOI=10.1101/gr.1474603;
RA   Raoult D., Ogata H., Audic S., Robert C., Suhre K., Drancourt M.,
RA   Claverie J.-M.;
RT   "Tropheryma whipplei twist: a human pathogenic Actinobacteria with a
RT   reduced genome.";
RL   Genome Res. 13:1800-1809(2003).
CC   -!- FUNCTION: Could be a nuclease involved in processing of the 5'-end of
CC       pre-16S rRNA. {ECO:0000255|HAMAP-Rule:MF_00651}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00651}.
CC   -!- SIMILARITY: Belongs to the YqgF nuclease family. {ECO:0000255|HAMAP-
CC       Rule:MF_00651}.
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DR   EMBL; AE014184; AAO44472.1; -; Genomic_DNA.
DR   RefSeq; WP_011096345.1; NC_004572.3.
DR   AlphaFoldDB; Q83GD2; -.
DR   SMR; Q83GD2; -.
DR   STRING; 203267.TWT_375; -.
DR   EnsemblBacteria; AAO44472; AAO44472; TWT_375.
DR   GeneID; 67388173; -.
DR   KEGG; twh:TWT_375; -.
DR   eggNOG; COG0816; Bacteria.
DR   HOGENOM; CLU_098240_0_0_11; -.
DR   OMA; PMGWTAQ; -.
DR   OrthoDB; 2075502at2; -.
DR   Proteomes; UP000002200; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0000967; P:rRNA 5'-end processing; IEA:UniProtKB-UniRule.
DR   CDD; cd16964; YqgF; 1.
DR   Gene3D; 3.30.420.140; -; 1.
DR   HAMAP; MF_00651; Nuclease_YqgF; 1.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR005227; YqgF.
DR   InterPro; IPR006641; YqgF/RNaseH-like_dom.
DR   InterPro; IPR037027; YqgF/RNaseH-like_dom_sf.
DR   PANTHER; PTHR33317; PTHR33317; 1.
DR   Pfam; PF03652; RuvX; 1.
DR   SMART; SM00732; YqgFc; 1.
DR   SUPFAM; SSF53098; SSF53098; 1.
DR   TIGRFAMs; TIGR00250; RNAse_H_YqgF; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Hydrolase; Nuclease; Reference proteome; Ribosome biogenesis.
FT   CHAIN           1..145
FT                   /note="Putative pre-16S rRNA nuclease"
FT                   /id="PRO_0000172167"
SQ   SEQUENCE   145 AA;  15923 MW;  A490C17999A33590 CRC64;
     MVKSVADRFF LGLDFGSTRI GVARNCGSLA VPVGVLPRAS CAEILGYISR YSIDEVVIGL
     PLTLAGKEKQ SARLAKEFSR FLVSSGVQVR FFDERFTTVI ATQKFYSLGK GVKQIRKCVD
     AAAATVMLQL FLDMEVKVDP LERKP