ID   YQHC_ECOLI              Reviewed;         318 AA.
AC   Q46855; Q2M9I9;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   30-MAY-2000, sequence version 2.
DT   03-AUG-2022, entry version 139.
DE   RecName: Full=Uncharacterized HTH-type transcriptional regulator YqhC;
GN   Name=yqhC; OrderedLocusNames=b3010, JW5849;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAA69177.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; U28377; AAA69177.1; ALT_INIT; Genomic_DNA.
DR   EMBL; U00096; AAC76046.2; -; Genomic_DNA.
DR   EMBL; AP009048; BAE77067.1; -; Genomic_DNA.
DR   PIR; H65087; H65087.
DR   RefSeq; NP_417483.2; NC_000913.3.
DR   RefSeq; WP_001350547.1; NZ_JACEFS010000030.1.
DR   AlphaFoldDB; Q46855; -.
DR   SMR; Q46855; -.
DR   BioGRID; 4262379; 29.
DR   BioGRID; 851808; 3.
DR   IntAct; Q46855; 6.
DR   STRING; 511145.b3010; -.
DR   jPOST; Q46855; -.
DR   PaxDb; Q46855; -.
DR   PRIDE; Q46855; -.
DR   EnsemblBacteria; AAC76046; AAC76046; b3010.
DR   EnsemblBacteria; BAE77067; BAE77067; BAE77067.
DR   GeneID; 947491; -.
DR   KEGG; ecj:JW5849; -.
DR   KEGG; eco:b3010; -.
DR   PATRIC; fig|1411691.4.peg.3720; -.
DR   EchoBASE; EB2833; -.
DR   eggNOG; COG2207; Bacteria.
DR   HOGENOM; CLU_000445_100_2_6; -.
DR   InParanoid; Q46855; -.
DR   OMA; LHKARML; -.
DR   PhylomeDB; Q46855; -.
DR   BioCyc; EcoCyc:G7563-MON; -.
DR   PRO; PR:Q46855; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0000987; F:cis-regulatory region sequence-specific DNA binding; IDA:EcoCyc.
DR   GO; GO:0001216; F:DNA-binding transcription activator activity; IMP:EcoCyc.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IMP:EcoCyc.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:GO_Central.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR018060; HTH_AraC.
DR   InterPro; IPR009594; Tscrpt_reg_HTH_AraC_N.
DR   Pfam; PF06719; AraC_N; 1.
DR   Pfam; PF12833; HTH_18; 1.
DR   SMART; SM00342; HTH_ARAC; 1.
DR   SUPFAM; SSF46689; SSF46689; 2.
DR   PROSITE; PS01124; HTH_ARAC_FAMILY_2; 1.
PE   4: Predicted;
KW   DNA-binding; Reference proteome; Transcription; Transcription regulation.
FT   CHAIN           1..318
FT                   /note="Uncharacterized HTH-type transcriptional regulator
FT                   YqhC"
FT                   /id="PRO_0000194618"
FT   DOMAIN          213..311
FT                   /note="HTH araC/xylS-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00593"
FT   DNA_BIND        230..251
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00593"
FT   DNA_BIND        278..301
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00593"
SQ   SEQUENCE   318 AA;  35957 MW;  87D5307551EF2D03 CRC64;
     MLQNCAQSNC RIIPKKLRDM KREEICRLLA DKVNKLKNKE NSLSGLLPDV RLLYGETPFA
     RTPVMYEPGI IILFSGHKIG YINERVFRYD ANEYLLLTVP LPFECETYAT SEVPLAGLRL
     NVDILQLQEL LMDIGEDEHF QPSMAASGIN SATLSEEILC AAERLLDVME RPLDARILGK
     QIIREILYYV LTGPCGGALL ALVSRQTHFS LISRVLKRIE NKYTENLSVE QLAAEANMSV
     SAFHHNFKSV TSTSPLQYLK NYRLHKARMM IIHDGMKASA AAMRVGYESA SQFSREFKRY
     FGVTPGEDAA RMRAMQGN