YQIR_BACSU
ID YQIR_BACSU Reviewed; 692 AA.
AC P54529;
DT 01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1996, sequence version 1.
DT 03-AUG-2022, entry version 151.
DE RecName: Full=Putative sigma L-dependent transcriptional regulator YqiR;
GN Name=yqiR; OrderedLocusNames=BSU24100;
OS Bacillus subtilis (strain 168).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=224308;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=168 / JH642;
RX PubMed=8969508; DOI=10.1099/13500872-142-11-3103;
RA Mizuno M., Masuda S., Takemaru K., Hosono S., Sato T., Takeuchi M.,
RA Kobayashi Y.;
RT "Systematic sequencing of the 283 kb 210 degrees-232 degrees region of the
RT Bacillus subtilis genome containing the skin element and many sporulation
RT genes.";
RL Microbiology 142:3103-3111(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=168;
RX PubMed=9384377; DOI=10.1038/36786;
RA Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA Yoshikawa H., Danchin A.;
RT "The complete genome sequence of the Gram-positive bacterium Bacillus
RT subtilis.";
RL Nature 390:249-256(1997).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Single-pass membrane
CC protein {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; D84432; BAA12593.1; -; Genomic_DNA.
DR EMBL; AL009126; CAB14341.1; -; Genomic_DNA.
DR PIR; H69961; H69961.
DR RefSeq; NP_390290.1; NC_000964.3.
DR RefSeq; WP_004398669.1; NZ_JNCM01000036.1.
DR AlphaFoldDB; P54529; -.
DR SMR; P54529; -.
DR STRING; 224308.BSU24100; -.
DR PaxDb; P54529; -.
DR PRIDE; P54529; -.
DR EnsemblBacteria; CAB14341; CAB14341; BSU_24100.
DR GeneID; 938666; -.
DR KEGG; bsu:BSU24100; -.
DR PATRIC; fig|224308.179.peg.2624; -.
DR eggNOG; COG3290; Bacteria.
DR eggNOG; COG3829; Bacteria.
DR InParanoid; P54529; -.
DR OMA; LEAKYTF; -.
DR PhylomeDB; P54529; -.
DR BioCyc; BSUB:BSU24100-MON; -.
DR Proteomes; UP000001570; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR CDD; cd00130; PAS; 2.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR002197; HTH_Fis.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR002078; Sigma_54_int.
DR InterPro; IPR025662; Sigma_54_int_dom_ATP-bd_1.
DR InterPro; IPR025943; Sigma_54_int_dom_ATP-bd_2.
DR InterPro; IPR025944; Sigma_54_int_dom_CS.
DR Pfam; PF02954; HTH_8; 1.
DR Pfam; PF00989; PAS; 2.
DR Pfam; PF00158; Sigma54_activat; 1.
DR PRINTS; PR01590; HTHFIS.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF46689; SSF46689; 1.
DR SUPFAM; SSF51735; SSF51735; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR SUPFAM; SSF55785; SSF55785; 2.
DR TIGRFAMs; TIGR00229; sensory_box; 2.
DR PROSITE; PS50112; PAS; 2.
DR PROSITE; PS00675; SIGMA54_INTERACT_1; 1.
DR PROSITE; PS00676; SIGMA54_INTERACT_2; 1.
DR PROSITE; PS00688; SIGMA54_INTERACT_3; 1.
DR PROSITE; PS50045; SIGMA54_INTERACT_4; 1.
PE 4: Predicted;
KW ATP-binding; Cell membrane; DNA-binding; Membrane; Nucleotide-binding;
KW Reference proteome; Repeat; Transcription; Transcription regulation;
KW Transmembrane; Transmembrane helix; Two-component regulatory system.
FT CHAIN 1..692
FT /note="Putative sigma L-dependent transcriptional regulator
FT YqiR"
FT /id="PRO_0000081386"
FT TRANSMEM 13..33
FT /note="Helical"
FT /evidence="ECO:0000255"
FT DOMAIN 115..185
FT /note="PAS 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00140"
FT DOMAIN 234..305
FT /note="PAS 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00140"
FT DOMAIN 368..598
FT /note="Sigma-54 factor interaction"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00193"
FT DNA_BIND 663..682
FT /note="H-T-H motif"
FT /evidence="ECO:0000250"
FT BINDING 396..403
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00193"
FT BINDING 460..469
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00193"
SQ SEQUENCE 692 AA; 77930 MW; A744812421421158 CRC64;
MQKVLIVGAG KRGTALLHIL IKTAIIDIIA VVDKDPEAPG LKEAEQYGIA VSSDWKPYIQ
QKPDIVIHTT GDQAVFDELL QRKHEDTIVM PGKMAYIVFQ LMEEKQHLIQ MLKEQTYKYD
RIFNSTHDGM IFIDINEEII LFNHMAEKMV GKKREEVIGR PIKEVIPSTK MPRILKTRVP
EYNQKQLLGD HLQIVTTRLP IIDEGGRLLG ALCVFKDITD AVELAEEVTN LKQVRTMLEA
IIQSSDEAIS VVDENGIGLL INKAYTKMTG LSEKEVIGKP ANTDISEGES MHLKVLETRR
PVRGVRMKVG PNEKEVIVNV APVIVDGILK GSVGVIHDVS EIKMLTAELN RARQIIRTLE
AKYTFDDIIG KSEQMLVALE QAKLGAKTPA TILLRGESGT GKELFAHAIH NESDRKYNKF
IRVNCAALSE NLLESELFGY EDGAFSGAKR GGKKGLFEEA NNGSIFLDEI GELTQNMQAK
LLRVLQEKEI VRVGGTKAIP VNVRVIAATN VNIEKAMADG TFREDLYYRI NRYPISIPPL
RQRLEDIEAL SVRLIQKINR DYGRNVKGLS QQALRALSAY HWPGNVRELE NVLGRAMIFL
NPHMEWIEKD HLPVFELEQK ENDTDQGTGF DFPDIEGEKL SVAVEKFEAH LIQQTLEKHH
FNRTKTAKAL GVSIRNLYYK MDKYGLANEG MQ