YQJ8_SCHPO
ID YQJ8_SCHPO Reviewed; 561 AA.
AC O74481;
DT 23-SEP-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1998, sequence version 1.
DT 03-AUG-2022, entry version 108.
DE RecName: Full=Uncharacterized protein C1840.08c;
DE Flags: Precursor;
GN ORFNames=SPCC1840.08c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000269|PubMed:16823372}; Single-pass membrane protein
CC {ECO:0000269|PubMed:16823372}. Golgi apparatus membrane
CC {ECO:0000269|PubMed:16823372}; Single-pass membrane protein
CC {ECO:0000269|PubMed:16823372}.
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DR EMBL; CU329672; CAA20131.1; -; Genomic_DNA.
DR PIR; T41176; T41176.
DR RefSeq; NP_588507.1; NM_001023497.2.
DR AlphaFoldDB; O74481; -.
DR BioGRID; 275921; 8.
DR STRING; 4896.SPCC1840.08c.1; -.
DR MaxQB; O74481; -.
DR PaxDb; O74481; -.
DR PRIDE; O74481; -.
DR EnsemblFungi; SPCC1840.08c.1; SPCC1840.08c.1:pep; SPCC1840.08c.
DR GeneID; 2539355; -.
DR KEGG; spo:SPCC1840.08c; -.
DR PomBase; SPCC1840.08c; -.
DR VEuPathDB; FungiDB:SPCC1840.08c; -.
DR eggNOG; KOG0191; Eukaryota.
DR HOGENOM; CLU_485840_0_0_1; -.
DR InParanoid; O74481; -.
DR OMA; YAPIFRS; -.
DR PhylomeDB; O74481; -.
DR PRO; PR:O74481; -.
DR Proteomes; UP000002485; Chromosome III.
DR GO; GO:0005783; C:endoplasmic reticulum; HDA:PomBase.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; ISO:PomBase.
DR GO; GO:0005794; C:Golgi apparatus; HDA:PomBase.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0003756; F:protein disulfide isomerase activity; ISO:PomBase.
DR GO; GO:0006621; P:protein retention in ER lumen; ISO:PomBase.
DR GO; GO:0030433; P:ubiquitin-dependent ERAD pathway; ISO:PomBase.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR SUPFAM; SSF52833; SSF52833; 1.
PE 3: Inferred from homology;
KW Endoplasmic reticulum; Golgi apparatus; Membrane; Reference proteome;
KW Signal; Transmembrane; Transmembrane helix.
FT SIGNAL 1..24
FT /evidence="ECO:0000255"
FT CHAIN 25..561
FT /note="Uncharacterized protein C1840.08c"
FT /id="PRO_0000350970"
FT TOPO_DOM 25..509
FT /note="Lumenal"
FT /evidence="ECO:0000255"
FT TRANSMEM 510..530
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 531..561
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
SQ SEQUENCE 561 AA; 64715 MW; 3ECB8F0E4213F96B CRC64;
MELGAWRSIL YIAFLFAITR HAFCKAVNLV HSPEGEEFEN ILSSVSATVE KKEVNNKLIM
PTANRDNQGV REELLVSSFK ERKLLNTNSA NLRLNSIGSY EMIDFKQINS EFFLSHRQHG
FVLFIDSKKK PRQSFYTDSA TSIVQLSKKY RNKIKFKSVD CASSLEKCEE IGINSFPSLV
YYNNAGQKKV FTAHTPYEVL SKHADLITEL DETDGKVYPQ SIIRLEEFKN LKANEPVFFL
YLHDYGSTPE DFDSLRIFAR YLVGFAPLYR TDDEKVIKTL NVTRLPHLVA IRHGVAFSYS
ERSVSAMRNT FQLIKWASLL KYPLVPELTP AVVENLDSDS YLAIALINPT SQVKASKAIS
TVQEIGLKWT LKLREVERKQ LLTAREKWWD HLRMLKQKGY DDVAFLAAEY SLPLPKNKKV
TFVWVNSLQW KTWISHTFHI DPMGPSRFVL MDPSRMFYWD SSAKGLPLTL DDSSLILDTT
FRVLAITGEG LPHEFSIPRG YVYLSEIKQY SSLILISLWI SLILFVSFLN RRLILHYSFE
SVHQLKTLTR KFIYSSLLKQ D
