ID   YQN2_CAEEL              Reviewed;         394 AA.
AC   Q09523;
DT   01-FEB-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1996, sequence version 1.
DT   03-AUG-2022, entry version 125.
DE   RecName: Full=Uncharacterized GTP-binding protein E02H1.2;
GN   ORFNames=E02H1.2;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like
CC       GTPase superfamily. Era GTPase family. {ECO:0000255|PROSITE-
CC       ProRule:PRU01050, ECO:0000305}.
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DR   EMBL; Z47075; CAA87384.1; -; Genomic_DNA.
DR   EMBL; Z36752; CAA87384.1; JOINED; Genomic_DNA.
DR   EMBL; Z36752; CAA85330.1; -; Genomic_DNA.
DR   EMBL; Z47075; CAA85330.1; JOINED; Genomic_DNA.
DR   PIR; T20419; T20419.
DR   RefSeq; NP_496060.1; NM_063659.1.
DR   AlphaFoldDB; Q09523; -.
DR   SMR; Q09523; -.
DR   STRING; 6239.E02H1.2; -.
DR   EPD; Q09523; -.
DR   PaxDb; Q09523; -.
DR   PeptideAtlas; Q09523; -.
DR   EnsemblMetazoa; E02H1.2.1; E02H1.2.1; WBGene00008456.
DR   GeneID; 174508; -.
DR   KEGG; cel:CELE_E02H1.2; -.
DR   UCSC; E02H1.2; c. elegans.
DR   CTD; 174508; -.
DR   WormBase; E02H1.2; CE01537; WBGene00008456; -.
DR   eggNOG; KOG1423; Eukaryota.
DR   GeneTree; ENSGT00390000013800; -.
DR   HOGENOM; CLU_038009_2_1_1; -.
DR   InParanoid; Q09523; -.
DR   OMA; WAEVDVI; -.
DR   OrthoDB; 586738at2759; -.
DR   PhylomeDB; Q09523; -.
DR   Reactome; R-CEL-5389840; Mitochondrial translation elongation.
DR   Reactome; R-CEL-5419276; Mitochondrial translation termination.
DR   PRO; PR:Q09523; -.
DR   Proteomes; UP000001940; Chromosome II.
DR   Bgee; WBGene00008456; Expressed in germ line (C elegans) and 4 other tissues.
DR   GO; GO:0005759; C:mitochondrial matrix; IBA:GO_Central.
DR   GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR   GO; GO:0043024; F:ribosomal small subunit binding; IBA:GO_Central.
DR   GO; GO:0019843; F:rRNA binding; IBA:GO_Central.
DR   GO; GO:0000028; P:ribosomal small subunit assembly; IBA:GO_Central.
DR   CDD; cd04163; Era; 1.
DR   Gene3D; 3.30.300.20; -; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR030388; G_ERA_dom.
DR   InterPro; IPR006073; GTP-bd.
DR   InterPro; IPR005662; GTP-bd_Era.
DR   InterPro; IPR015946; KH_dom-like_a/b.
DR   InterPro; IPR009019; KH_sf_prok-type.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR005225; Small_GTP-bd_dom.
DR   PANTHER; PTHR42698; PTHR42698; 1.
DR   Pfam; PF01926; MMR_HSR1; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   SUPFAM; SSF54814; SSF54814; 1.
DR   TIGRFAMs; TIGR00231; small_GTP; 1.
DR   PROSITE; PS51713; G_ERA; 1.
PE   3: Inferred from homology;
KW   GTP-binding; Nucleotide-binding; Reference proteome.
FT   CHAIN           1..394
FT                   /note="Uncharacterized GTP-binding protein E02H1.2"
FT                   /id="PRO_0000122488"
FT   DOMAIN          32..280
FT                   /note="Era-type G"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01050"
FT   REGION          40..47
FT                   /note="G1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01050"
FT   REGION          66..70
FT                   /note="G2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01050"
FT   REGION          87..90
FT                   /note="G3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01050"
FT   REGION          160..163
FT                   /note="G4"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01050"
FT   REGION          259..261
FT                   /note="G5"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01050"
FT   BINDING         40..47
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000250"
FT   BINDING         87..91
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000250"
FT   BINDING         160..163
FT                   /ligand="GTP"
FT                   /ligand_id="ChEBI:CHEBI:37565"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   394 AA;  43892 MW;  6521C28D32952BA9 CRC64;
     MIIKRLNFSC RLFSTASTST SYEKTPIQPA TKCLQLAVIG APNVGKSLLT NSLIRCPLSA
     VSSKMDTTTR NISASICSDS TQLVFVDSPG AVSTSHVRQT MKKTSATSGD RVLQDPERAL
     QRAQHVLVVQ DSTAPGAYIH HRVLHMLHRY SHVPSILVMN KIDLVMRRSD LLPLVEILTN
     GQLSDNQQIS TKPAQIGRLG KSLSTNIQSS SSFKPSDEKW QSQFRELIQK PTWKCSYSET
     RSLFRTICGW SGFERVFFVS SLNGEGIDEL RDHLMSISPQ GEWKMQDGMP TGESAQQLCI
     DSIRAAVLDT TPSDVAYTVQ IRISEWEEQG EVLQIVGEIR CQKPRDGSLI IGKGGKRISE
     IGRRVNEHLH SLFQRQLYAR LIVTHNGKLI TQSK