YQO5_SCHPO
ID YQO5_SCHPO Reviewed; 576 AA.
AC Q9Y7S4;
DT 05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1999, sequence version 1.
DT 25-MAY-2022, entry version 123.
DE RecName: Full=Uncharacterized transporter C569.05c;
GN ORFNames=SPCC569.05c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1] {ECO:0000312|EMBL:CAB42066.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2] {ECO:0000305}
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum
CC {ECO:0000269|PubMed:16823372}. Golgi apparatus
CC {ECO:0000269|PubMed:16823372}. Membrane {ECO:0000255}; Multi-pass
CC membrane protein {ECO:0000255}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. CAR1 family.
CC {ECO:0000255}.
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DR EMBL; CU329672; CAB42066.1; -; Genomic_DNA.
DR PIR; T41407; T41407.
DR RefSeq; NP_588568.1; NM_001023555.2.
DR AlphaFoldDB; Q9Y7S4; -.
DR SMR; Q9Y7S4; -.
DR BioGRID; 276112; 2.
DR STRING; 4896.SPCC569.05c.1; -.
DR MaxQB; Q9Y7S4; -.
DR PaxDb; Q9Y7S4; -.
DR EnsemblFungi; SPCC569.05c.1; SPCC569.05c.1:pep; SPCC569.05c.
DR GeneID; 2539551; -.
DR KEGG; spo:SPCC569.05c; -.
DR PomBase; SPCC569.05c; -.
DR VEuPathDB; FungiDB:SPCC569.05c; -.
DR eggNOG; KOG0255; Eukaryota.
DR HOGENOM; CLU_008455_11_4_1; -.
DR InParanoid; Q9Y7S4; -.
DR OMA; KNFSRPM; -.
DR PhylomeDB; Q9Y7S4; -.
DR PRO; PR:Q9Y7S4; -.
DR Proteomes; UP000002485; Chromosome III.
DR GO; GO:0005783; C:endoplasmic reticulum; HDA:PomBase.
DR GO; GO:0005794; C:Golgi apparatus; HDA:PomBase.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; ISO:PomBase.
DR GO; GO:0015606; F:spermidine transmembrane transporter activity; ISO:PomBase.
DR GO; GO:0000297; F:spermine transmembrane transporter activity; ISO:PomBase.
DR GO; GO:0022857; F:transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:1903711; P:spermidine transmembrane transport; IC:PomBase.
DR GO; GO:1903710; P:spermine transmembrane transport; IC:PomBase.
DR GO; GO:0055085; P:transmembrane transport; IBA:GO_Central.
DR Gene3D; 1.20.1250.20; -; 1.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR Pfam; PF07690; MFS_1; 1.
DR SUPFAM; SSF103473; SSF103473; 1.
DR PROSITE; PS50850; MFS; 1.
PE 3: Inferred from homology;
KW Endoplasmic reticulum; Golgi apparatus; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..576
FT /note="Uncharacterized transporter C569.05c"
FT /id="PRO_0000372794"
FT TRANSMEM 149..169
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 173..193
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 200..220
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 231..251
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 261..281
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 291..311
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 366..386
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 401..421
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 446..466
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 472..492
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 503..525
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 542..562
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 1..40
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 576 AA; 63711 MW; 3BB36A301FE9FD7A CRC64;
MSTNPNAGIQ PLTNSISQSA SAHPELYHTT SHESVSTYQL QSQLSHSATS NLSTAANFHT
RPPIANDENA QNLSTVNSSH SSELSKANLV DVEKCIQDPL LQIFPTVEDP DRFVFSIDPK
SPLIAVNWPF RKKLKITCVY SYVALCSTFA SSVFSVPAEA ITTIFHISLT VSLLTMTVFL
CGYIAGPIVW APLSELSGRK LPLLIGMFGF GIFNISVAVA KDIQTIMMCR FFSGFFASAP
LTVVAAAFAD MYSNKHRGTA ITIFAALVFD GPLVSPIIGG FLTKSYLGWR WTEYITSFMG
FFALVIVYLF CDETYSKAII RNKAKEYRAM SGNYFVHAKS EEEVLTVPDV AKNYLLVPMK
LLFTEPIVFL ITLYSSFVYA ILYLLLEAYP IIFSEKRHFS MGVAELPYIG LLVGVFIGSA
INISFEPWYY RRCLALGGKP DPEARLPPMM IGCFMFPAGI FWLSWSGYYS YVHWIVPTLS
GLATGCGILL IFLQCLNYLI DAYLFRAASA VAANTIMRSA MAAGFPLFAV QMFHNMGVGW
AGSLLGFIAV ALIPMPFAFF FFGRKIREKS KMAVVL
