YQOA_CAEEL
ID YQOA_CAEEL Reviewed; 738 AA.
AC Q09299; Q2V4U6; Q7JPI7; Q8IG36;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 16-MAY-2006, sequence version 3.
DT 03-AUG-2022, entry version 128.
DE RecName: Full=Putative RNA-binding protein EEED8.10;
GN ORFNames=EEED8.10;
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
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DR EMBL; FO081042; CCD68738.1; -; Genomic_DNA.
DR PIR; T15920; T15920.
DR RefSeq; NP_001040757.1; NM_001047292.3.
DR AlphaFoldDB; Q09299; -.
DR SMR; Q09299; -.
DR BioGRID; 39263; 1.
DR STRING; 6239.EEED8.10a; -.
DR iPTMnet; Q09299; -.
DR EPD; Q09299; -.
DR PaxDb; Q09299; -.
DR PeptideAtlas; Q09299; -.
DR EnsemblMetazoa; EEED8.10a.1; EEED8.10a.1; WBGene00017138.
DR GeneID; 173919; -.
DR KEGG; cel:CELE_EEED8.10; -.
DR UCSC; EEED8.10a; c. elegans.
DR CTD; 173919; -.
DR WormBase; EEED8.10a; CE39344; WBGene00017138; -.
DR eggNOG; KOG1947; Eukaryota.
DR GeneTree; ENSGT00940000155184; -.
DR HOGENOM; CLU_382731_0_0_1; -.
DR InParanoid; Q09299; -.
DR OMA; SIAFQHT; -.
DR OrthoDB; 306542at2759; -.
DR PhylomeDB; Q09299; -.
DR Reactome; R-CEL-8951664; Neddylation.
DR Reactome; R-CEL-983168; Antigen processing: Ubiquitination & Proteasome degradation.
DR PRO; PR:Q09299; -.
DR Proteomes; UP000001940; Chromosome II.
DR Bgee; WBGene00017138; Expressed in pharyngeal muscle cell (C elegans) and 4 other tissues.
DR GO; GO:0019005; C:SCF ubiquitin ligase complex; IBA:GO_Central.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IBA:GO_Central.
DR Gene3D; 3.30.70.330; -; 1.
DR Gene3D; 3.80.10.10; -; 2.
DR InterPro; IPR001810; F-box_dom.
DR InterPro; IPR006553; Leu-rich_rpt_Cys-con_subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR Pfam; PF00076; RRM_1; 1.
DR SMART; SM00367; LRR_CC; 5.
DR SMART; SM00360; RRM; 1.
DR SUPFAM; SSF54928; SSF54928; 1.
DR PROSITE; PS50181; FBOX; 1.
DR PROSITE; PS50102; RRM; 1.
PE 4: Predicted;
KW Reference proteome; RNA-binding.
FT CHAIN 1..738
FT /note="Putative RNA-binding protein EEED8.10"
FT /id="PRO_0000065273"
FT DOMAIN 112..201
FT /note="RRM"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT DOMAIN 239..297
FT /note="F-box"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00080"
FT REGION 211..237
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 221..237
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 738 AA; 81188 MW; DEBEA73BECF1D267 CRC64;
MDFNRSFTSN LGSAGSAKSQ QSMFKALRRL HGQNLESRGL HDMTEAFQSF VTRARFFSIG
KLRRTWSHSA AEFMKYRRLL PMLLADGDAF DGGETDDFDA SIAFQHTSRD DRKIVVSNIS
AKVTQSQLQS FFSQYGKITS CILPREEKKT SVFGTLPKHS RNCGTATITF KKSEHADRAK
NANPEELKFY DQVMVVSAYV SKKRGGKGLV LSDDVGSRED TPLSRASSTQ SLASGSEQSF
NLGNVPDKIL RRVISFLPIH ETIRLERVNK KFMEESIKSW ELVNKIALAR ETVFNKQRPM
RTSHLKAILT RAGAHLRSLD VSGIVHLLDD RRALKVIATC CPNLVDLDIS GTHAQAEALE
ELGESLSHLE QLSYRGMETT GDKAFYFLLK NCGHSLKFVD LRNSKRLHGR SFKLFGSQLE
SLYLDGSSKV DEMAFEDLCT SCGGLKELRI NECYKITDEN LSMIARRMED LSILTLCGDG
FKSLTSAGLI HISHMRNITE LALDYNALVN DELLISISAG LPLLSSLSLA NAGNDSSITA
EGVSAIKNLK ELTQLDASSL AAVNSKVLEQ LGSLKKLEII QLRNCTYLGD DGVRAKLRMP
NIRHVDLSGS ILVSNDSIQQ FIKAFPSGPK LPPITLVVGG TAADASKLSV RGSRVVVDFS
DYSTIVTMQT SQCSSSKFAI GGSASDAEGS DDEFEALTAQ RSFYIDAVCG EEESPITDDG
KLAEWAEKEA RSLGLIKD