YQU3_CAEEL
ID YQU3_CAEEL Reviewed; 1312 AA.
AC Q09550; B5BM18; B5BM19; B5BM20; B5BM21;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 16-MAY-2012, sequence version 4.
DT 03-AUG-2022, entry version 119.
DE RecName: Full=Uncharacterized protein F26C11.3;
DE Flags: Precursor;
GN ORFNames=F26C11.3;
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND ALTERNATIVE SPLICING.
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=5;
CC Name=b;
CC IsoId=Q09550-1; Sequence=Displayed;
CC Name=a;
CC IsoId=Q09550-2; Sequence=VSP_043607, VSP_043611;
CC Name=c;
CC IsoId=Q09550-3; Sequence=VSP_043610;
CC Name=d;
CC IsoId=Q09550-4; Sequence=VSP_043608;
CC Name=f;
CC IsoId=Q09550-5; Sequence=VSP_043609;
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DR EMBL; Z47072; CAA87369.4; -; Genomic_DNA.
DR EMBL; Z47072; CAR31484.2; -; Genomic_DNA.
DR EMBL; Z47072; CAR31485.2; -; Genomic_DNA.
DR EMBL; Z47072; CAR31486.2; -; Genomic_DNA.
DR EMBL; Z47072; CAR31487.2; -; Genomic_DNA.
DR PIR; T21389; T21389.
DR RefSeq; NP_001129813.2; NM_001136341.2.
DR RefSeq; NP_001129814.2; NM_001136342.2.
DR RefSeq; NP_001129815.2; NM_001136343.2.
DR RefSeq; NP_001129816.2; NM_001136344.2.
DR RefSeq; NP_496139.4; NM_063738.4.
DR AlphaFoldDB; Q09550; -.
DR STRING; 6239.F26C11.3b; -.
DR PaxDb; Q09550; -.
DR EnsemblMetazoa; F26C11.3a.1; F26C11.3a.1; WBGene00009147.
DR EnsemblMetazoa; F26C11.3b.1; F26C11.3b.1; WBGene00009147.
DR EnsemblMetazoa; F26C11.3c.1; F26C11.3c.1; WBGene00009147.
DR EnsemblMetazoa; F26C11.3d.1; F26C11.3d.1; WBGene00009147.
DR EnsemblMetazoa; F26C11.3f.1; F26C11.3f.1; WBGene00009147.
DR UCSC; F26C11.3; c. elegans. [Q09550-1]
DR WormBase; F26C11.3a; CE46401; WBGene00009147; -. [Q09550-2]
DR WormBase; F26C11.3b; CE46248; WBGene00009147; -. [Q09550-1]
DR WormBase; F26C11.3c; CE46189; WBGene00009147; -. [Q09550-3]
DR WormBase; F26C11.3d; CE46533; WBGene00009147; -. [Q09550-4]
DR WormBase; F26C11.3f; CE46310; WBGene00009147; -. [Q09550-5]
DR eggNOG; ENOG502S5I0; Eukaryota.
DR InParanoid; Q09550; -.
DR OMA; LTAYKNC; -.
DR OrthoDB; 1710086at2759; -.
DR PRO; PR:Q09550; -.
DR Proteomes; UP000001940; Chromosome II.
DR Bgee; WBGene00009147; Expressed in material anatomical entity and 2 other tissues.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR CDD; cd00033; CCP; 1.
DR InterPro; IPR042312; F26C11.3-like.
DR InterPro; IPR035976; Sushi/SCR/CCP_sf.
DR InterPro; IPR000436; Sushi_SCR_CCP_dom.
DR PANTHER; PTHR40289; PTHR40289; 8.
DR SMART; SM00032; CCP; 1.
DR SUPFAM; SSF57535; SSF57535; 1.
DR PROSITE; PS50923; SUSHI; 1.
PE 3: Inferred from homology;
KW Alternative splicing; Disulfide bond; Reference proteome; Secreted; Signal;
KW Sushi.
FT SIGNAL 1..20
FT /evidence="ECO:0000255"
FT CHAIN 21..1312
FT /note="Uncharacterized protein F26C11.3"
FT /id="PRO_0000014282"
FT DOMAIN 1239..1306
FT /note="Sushi"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00302"
FT REGION 299..503
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 565..609
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 645..692
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 749..775
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 811..864
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 898..942
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1048..1079
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1114..1165
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 571..609
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 656..692
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 1241..1291
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00302"
FT DISULFID 1273..1304
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00302"
FT VAR_SEQ 1..85
FT /note="MRNNLIYTMFLSCLHFETFCQNTTTSNDDCEALSQDLDNKNPVECCTTEAFD
FT FLDKKYPNWRKVNKYVRSPYINELRFMGCCNKT -> MTLVRNLVVISLLIPKIIAFDC
FT FWLSNPIYNNGLCCTPQAVSYLDNKHSPVWRMSISNINLVADIYINDAMAQGLCRSS
FT (in isoform a)"
FT /evidence="ECO:0000305"
FT /id="VSP_043607"
FT VAR_SEQ 2..111
FT /note="RNNLIYTMFLSCLHFETFCQNTTTSNDDCEALSQDLDNKNPVECCTTEAFDF
FT LDKKYPNWRKVNKYVRSPYINELRFMGCCNKTISTSAILTTTPLTTSSTTLEIYTTDS
FT -> KNKFICLILLCSLLSGTFCQGQRYHCGRAFGDLDIQNTSECCNSAAYEYLETKYSQ
FT LWFSSSEENRTAYFYELKSNGFCGNNSSTASIATTEEVTTSLTTLEPSTADL (in
FT isoform d)"
FT /evidence="ECO:0000305"
FT /id="VSP_043608"
FT VAR_SEQ 2..111
FT /note="RNNLIYTMFLSCLHFETFCQNTTTSNDDCEALSQDLDNKNPVECCTTEAFDF
FT LDKKYPNWRKVNKYVRSPYINELRFMGCCNKTISTSAILTTTPLTTSSTTLEIYTTDS
FT -> QLSVLLCIFLTLLTRTSLCQTVDCNWLALPNYLMNYNKECCTSESVTYLNTKYGQD
FT WKKAWLDRVNYVTELKSNGICGVLAFKTTTIETSTKFIPIVRI (in isoform f)"
FT /evidence="ECO:0000305"
FT /id="VSP_043609"
FT VAR_SEQ 4..111
FT /note="NLIYTMFLSCLHFETFCQNTTTSNDDCEALSQDLDNKNPVECCTTEAFDFLD
FT KKYPNWRKVNKYVRSPYINELRFMGCCNKTISTSAILTTTPLTTSSTTLEIYTTDS ->
FT KLVYSAILVSFLLSETVCQSLGFYPCSSLTRGLDSENSSECCTKDAFNYLYSKDLFWPN
FT RSNETRSSYISELRSKGYCRISSSTFLFSTTEELTTTLTISETSTTDF (in
FT isoform c)"
FT /evidence="ECO:0000305"
FT /id="VSP_043610"
FT VAR_SEQ 87..111
FT /note="Missing (in isoform a)"
FT /evidence="ECO:0000305"
FT /id="VSP_043611"
SQ SEQUENCE 1312 AA; 140460 MW; 25BC2E10B0979D4C CRC64;
MRNNLIYTMF LSCLHFETFC QNTTTSNDDC EALSQDLDNK NPVECCTTEA FDFLDKKYPN
WRKVNKYVRS PYINELRFMG CCNKTISTSA ILTTTPLTTS STTLEIYTTD SDSTTAETTS
VPTTTTSIQC GVLANTSCCN LKVTECLSKQ YEDWRNVTLI KGYERELEKC DCVLTSSSTE
TGTVKFLDRE FFRVFSSAEI ASTTSLPTTT SPSLNCYWLS EPSNFSEWID GKQTNLRYNG
GCCSETSIQV LNSSDSTRWI LTTSDSWNKA NALINLLYCT PNACPQQSML WTNCSNLSTT
TSSSTMLSST TLLTTETETR ESSSTGSTQT TTPSTEPSTT ITTPMEQSST VSSVQKTRTS
EDKPSSSTTV PTSASTSESS TSSPMAETSS SSTTSQSSPA STSTVPESST VGSTPTTGLT
TLSTNEQSTS TSSGGHSTST FGTTSETPET STDFTATSTS SSSDSSTQSS NAQTSTIENG
STTTNFTSAP STSSTPATPT TTYNWPTGGT TWMLPSGEIV QAHKTFFSSF NYFQVLSESL
IAYPNCTTVL MQLIYNPRTK ETRTEITSDA EGCKKTSSTP TPSSTSVHST TATPSTTPGT
TTYNWPTGGT TRMLPSGEII LSESLIAYPN CTTVLMQLIY NPSTKETRTE TTTDADGCKK
TSSTSSSTPS LKHSTTPTPT PGTTTYNWPT GGTTRMLPSG EIILSESLIA YPNCTTVLMQ
LIYTPSTNKT RTETTTDTEG CKKTSTISSS SSKFSITPTP TPSSGTTTYN WPTGGTTRTL
PSGEIILSES LIAFQNCTTV LMQLIYNPST NKTRTETTTD AEGCKKTSST SKISTTPTSP
TSSKPTPTST SMTTTYNWPT GGTTRTLPSG EIILSESLIA YKNCTTVLMQ LIYNPSTNKT
RTETTTDAQG CKATSSTSLK PTSPSSSTAS PPTTTYNWPT GGTTRTLPSG EIILSESLIA
YKNCTTVLMQ LIYNPSTNKT RTETTTDAQG CKATITTPTP ITTTYNWPTG GTTRTLPSGE
IILSESLIAY KNCTTVLMQL IYNPSTNKTR TETTSDAQGC KATSTTQTPT TFNWPTGGTT
RTLPSGEIIL SESLIAYKNC TTVLMQLIYN PSKNTTRTET TSDAEGCKAT SSGTTSTMSP
GTTGGTTVSR TTNSNNPIDS STLETTTFAW PTGGTTRMLP SGEIIISESL TAFPNCTTVL
KQLVYNPTTN TTRTDTISDS EGCKATSTAK PTTVISSTAT CSSLNLNLNS TTRPTSSEIK
DSYSVGEKIY HICEKDYSFE IALQPLKIYQ CLNGGAWSGT PEKCVATGKS EL
